查询词典 flanking

In this article, by exploiting flanking markers through the widely applied half-sib design, we have developed the structures of three variance components, i.e., variance component between marker genotypes, polygenic variance component and recombinant variance component within marker genotypes.

该文在侧翼标记情况下利用广泛使用的半同胞设计提出了3种方差组分，即标记组间方差、组内多基因方差和组内重组方差及其构成。

Methods Four probands from four unrelated families with typical manifestations of CADASIL were studied The 1～12 coding exons and their flanking intron sequences of NOTCH3 gene were amplified by PCR and sequenced Some family members in the pedigree 2 and 4 were also examined for the NOTCH3 gene mutations Results Four hete...

结果 4个家系中的先证者均发现有NOTCH3基因的杂合性错义突变，先证者 1为外显子 3的 2 6 8C→T突变，先证者 2为外显子 3的 32 2C→T突变，先证者 3为外显子 3的 32 8C→T突变，先证者 4为外显子 11的 1819C→T突变，分别造成Notch3蛋白质R90C、C10 8R、R110C和R6 0 7C 4个位点氨基酸的替换。

In addition to these basic components, the conditional gene targeting construct had two loxp placed in the same orientation flanking the essential functional part of KIF1A gene-an exon which contains a ATP-binding consensus P-loop of the motor domain. We also carried a number of important considerations that have to be taken into account to generate a successful design for a KIF 1A conditional null allele.

除了上述基本特点之外，条件性基因剔除更主要的特点是，插入了3个方向相同的loxp位点，其中两个夹住了KIF1A的一段基本功能单位—一个包含了KIF1A运动区中和ATP结合的P-loop的外显子部位。

The two long-faced Jewish officials flanking them looked like they hadn't heard a joke in months.

pavel：&在一幅摄于阿根廷足联办公室关于调解的照片上&疑有误

Next to him, in a staged picture of reconciliation at the offices of the Argentine Football Association was Grondona sporting a 'Please can I go and hide in the cupboard' lopsided grin. The two long-faced Jewish officials flanking them looked like they hadn't heard a joke in months.

在一幅摄于阿根廷足联办公室关于调解的照片上，在他旁边的就是带着&请饶了我吧&的傻笑的格隆多纳，站在他边上的两名犹太官员拉长了脸，象是几个月没开过笑颜一样。

EF116490. Characterization and comparison of this sequence with mouflons, goat, cattle and European bison orthologues were also conducted. Results showed that: 1 The 5'-flanking region contained many potential transcriptional factor binding sites such as those for C/EBPb, C/EBP, SP1, Cap, USF, HFH-2, HNF-3b, and Oct-1, which might have an important effect on transcription activation and regulation as well as tissue-specific expression.

EF116490，在分析其序列结构特征的基础上与GenBank中摩弗伦羊、山羊、普通牛、欧洲野牛进行了比较基因组学和系统进化研究，结果表明：(1)欧拉型藏绵羊GHR基因启动子P1区存在C/EBP、C/EBPb、SP1、Cap、USF、HFH-2、HNF-3b、Oct-1等多个潜在的转录因子结合位点，可能与GHR基因的转录调控和起始以及特异表达有关。

The atmosphere of the simple home suggested by black iron trivets and World' s Fair souvenir plates on the walls flanking the window.

那个黑色的金属支锅架和挂在窗户两侧墙上的那些在世界博览会上买的装饰盘烘托出了这间简朴的房间里的气氛。

Every element of the picture was perfect: the grandfather in his plain work clothes, his white hair back lighted by sunshine, the child's form wrapped in the sheet, the atmosphere of the simple home suggested by black iron trivets and World's Fair souvenir plates on the walls flanking the window.

这张照片的每个细节都将完美无缺：祖父穿着朴素的工作服，阳光从后面照射着他的白发，孩子的躯体裹在白床单里，那个黑色的金属支锅架和挂着窗户两侧墙上的那些在世界博览会上买的装饰盘烘托出了这间简朴的房间里的气氛。

Every element of the picture was perfect: the grandfather in his plain work clothes, his white hair backlighted by sunshine, the child's form wrapped in the sheet, the atmosphere of the simple home suggested by black iron trivets and World's Fair souvenir plates on the walls flanking the window.

这张照片的每个细节都将完美无缺：祖父穿着朴素的工作服，阳光从后面照射着他的白发，孩子的躯体裹在白床单里，那个黑色的金属支锅架和挂着窗户两侧墙上的那些在世界博览会上买的装饰盘''。'烘托'。''出了这间简朴的房间里的气氛。

The 4.4 kb or 2.7 kb of 5'-flanking region of the human CYP11A1 gene was fused to the Cre recombinase and the transgenes were injected to the ROSA26 heterozygote pronuclei by microinjection.

为了了解CYP11A1基因的转录调控，我们利用SCC-Cre/R26R动物模式，建立了SCC-iCre暂时性基因转殖小鼠，探讨CYP11A1启动子在脑内的表现活性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。