查询词典 five-fold

They found that the incidence of tonsillar cancer rose by 2.8-fold in Sweden during the study period.

他们发现瑞典扁桃体癌症的发生率在研究期间提高了2.8倍。

In the county of Stockholm, between 1970 and 2002, we have previously reported a 3-fold parallel increase in the incidence of tonsillar squamous cell carcinoma and the proportion of human papillomavirus positive tonsillar SCC.

我们曾报告1970年和2002年间，斯德哥尔摩地区扁桃体鳞状细胞癌的发病率和扁桃体鳞状细胞癌中人乳头瘤病毒阳性率呈3倍平行性增长。

Reactive oxygen species causing DNA oxidative damage comes from two kinds of ways:one is from cellular normal physiological metabolism;the other is from outer environment.Redox-sensitive green fluorescent protein was expressed in Saccharomyces cerevisiae.Recombinant cells were evaluated in monitoring the changes in the redox state of living cells when challenged with toxicologically relevant metal ions NaAsO_2 or Pb(NO_3)_2 by measuring emission intensity at 510 nm with a Hitachi F6500 fluorescence spectrophotometer,roGFP expressed in yeast responded not only to typical membrane-permeant oxidants H_2O_2 and reductants DTT,but also to toxicological metal ion-induced intracellular redox changes in a dose-dependent manner.Moreover,exposure of yeast cells to NaAsO_2 or Pb(NO_3)_2 at concentrations that induced redox changes reported by roGFP caused up to 2～3 fold increases in DNA mutation frequency.This mutagenic effect was largely caused by oxidative stress since blocking the production of hydryl radicals with thiourea significantly reduced the mutation rate as well as delayed the cell death.

本文将对氧化还原状态变化敏感的绿色荧光蛋白roGFP1-R12，在酵母细胞中实现了多拷贝强表达；荧光扫描经强氧化剂H_2O_2和还原剂DTT以及环境中重金属NaAsO_2或Pb(NO_3)_2处理后的酵母细胞悬液，测定510 nm处的荧光发射强度结果显示，表达的绿色荧光蛋白对氧化还原水平敏感，且在510 nm处的荧光强度与一定的重金属浓度呈正相关，即roGFP1-R12在510nm处的荧光发射值随重金属浓度的增高而增强，从而说明重金属对细胞的毒性在一定程度上很可能是通过破坏细胞内的氧化还原平衡发生作用；同时通过该绿色荧光蛋白对胞内氧化还原状态变化的响应情况可以来实时检测环境中的重金属；遗传学的点突变频率及致死率实验数据表明，重金属能导致菌体的点突变频率和致死率升高，且活性氧的清除剂巯基脲能明显降低这种点突变和致死率，说明由重金属引发的这种点突变和致死效应在很大程度上是依赖于重金属对细胞诱导产生的氧化胁迫。

Furthermore, large-scale fold and fault structure hasn't been found around the Tianchi Lake, but the original prismatic joints and radial joints developed well in the trachyte, so the rock mass is dissected into fractured fragmental structure and the integration of rock mass is further destroyed.

在构造方面，长白山天池周围虽然没有发现大规模的褶皱断裂构造，但粗面岩中原生柱状节理、放射状节理十分发育，这些节理裂隙将岩体切割成十分破碎的碎裂结构，使岩体极易产生岩崩、落石，使岩体的完整性遭到了进一步的破坏。

The major deposits in the Sanzhou ore field are related to Yanshanian or later tectonic activity,which is divisible into six sequences represented by:1the Upper Triassic-Lower Jurassic low-angle normal slip fault and associated structures near or immediately occurring on the unconformity between the Lower Carboniferous and the Upper Triassic;2the longitudinally bucking fold in Devonian-Carboniferous and Upper Triassic-Lower Jurassic strata;3the earlier phase thrusts toward northwest;4the transcurrent fault toward northeast;5the later phase thrusts toward northwest;and 6the extensional normal slip minor faults.

彭少梅 ，杨坤光，姚淑梅三洲矿田内主要矿床与燕山期或更晚的构造活动有关。燕山期构造活动可分为六个序列：1下石炭统与上三叠统不整合面附近和不整合面之上的上三叠统―下侏罗统中的低角度正滑断层及伴生构造，2泥盆系―石炭系及上三叠统―下侏罗统中的纵弯褶皱，3北西向逆冲断层，4北东向平移断层，5第二次北西向逆冲断层，6伸展性正滑小断层。

Methods: Ten adult cadaver heads were carefully examined by way of the transcallosal transchoroidal approach and the transfrontal transchoroidal approach under microscope with 10-fold magnification.

10例成人头颅标本，在放大10倍手术显微镜下分别依照经胼胝体一侧脑室-脉络裂入路和经额中回-侧脑室-脉络裂入路进行解剖观察。

To determine the role of neutral trehalase during storage stability of spores, we constructed a M.anisopliae RNAi transformant and an overexpression transformant. Analysis of these transformants revealed that the expression level of the neutral trehalase gene in RNAi transformant(No 688) was reduced to 50% of which found in wild type and the overexpression transformant(No 113) showed approximatlely 2-fold higher levels of neutral trehalase mRNA than that found in wild-type control.

构建了中性海藻糖酶基因RNA干扰载体和超表达载体，采用电转法和基因枪法转化金龟子绿僵菌CQMa102，获得了RNA干扰转化子和超表达转化子，比较这两种转化子和出发菌株的mRNA表达情况，发现RNA干扰转化子中性海藻糖酶mRNA表达受到抑制，而超表达转化子中性海藻糖酶mRNA的表达量是出发菌株的2倍。

Analysis of these mutants revealed that the expression level of the neutral trehalase gene in RNAi mutant (Ma688 strain) was reduced to 42% of which found in wild-type strain and the over-expression mutant (Ma113 strain) showed approximatlely 2-fold higher levels of neutral trehalase mRNA than that found in wild-type control. Then the transformants Ma688 and Ma113 were chosen for closer examination, including trehalose content, storage longevity , thermotol

利用Northern blot 分析这几个突变菌株中性海藻糖酶基因mRNA 的含量，选择中性海藻糖酶基因超表达2 倍和中性海藻糖酶基因被抑制到42%的两个转化菌：Ma113 和Ma688，将其与出发菌株进行分生孢子内海藻糖含量的测定，孢子储藏

Combined as a hard, durable mineral they transform into a triagonal stone with a six fold surface.

合并为一个硬盘，持久矿产他们转变为一个triagonal石头的表面的6倍。

In this study, isolate 23 microbes with lipase activity from Wu-Jie scrap heap at Ilan and Taichung Environmental Protection Section. When the microbes incubator in 50oC, there are isolates B61 and M63 that lipase activity are better than others. Brevibacillus borstelensis SH168 isolated from NTU resterant food waste compost is used as control check. Isolates B61, M63 and Brevibacillus borstelensis SH168 determine the lipase activity by the LB with tributyrin. The lipase activity of isolates B61 and M63 are 2~3 fold higher than Brevibacillus borstelensis SH168. So isolates B61 and M63 are more useful in producing lipase. Isolate B61 can grow at pH 5~9, and at temperature 20oC ~ 60oC; isolate M63 can grow at pH 6~10, and at temperature 30oC ~ 50oC. Isolates B61 and M63 were identified by 16S rRNA. Isolate B61 is Bacillus circulans, and isolate M63 is Bacillus species.

本研究，於宜兰五结垃圾场和台中市环保局厨余堆肥样品中共分离出 23 株具脂肪酶活性菌株， 23 株菌株中经过三油酸甘油酯的洋菜培养基於 50℃培养 5 天后，发现有 2 株菌的脂肪酶活性较强，分别为分离株 B61 和 M63；以本实验室先前自台大女九餐厅蔬果厨余堆肥中所筛选出的耐高温脂解菌 Brevibacillus borstelensis SH168作为本实验对照菌株，将分离株 B61、M63 及 Brevibacillus borstelensis SH168 3 株菌株於含有三酪酸甘油酯液态培养基培养并测定其脂肪酶活性，发现分离菌株之活性皆比 Brevibacillus borstelensis SH168 高出 2~3 倍，认为分离株 B61、M63 适於产生脂肪酶的菌株，分离株 B61 在 pH 5~9 皆可生长，生长温度介於 20 oC ~ 60oC；分离株 M63 在 pH 6~10 可生长，生长温度介於 30 oC ~ 50oC； 2 株分离菌株以 16S rRNA定序结果分离株 B61 为 Bacillus circulans，分离株 M63 为 Bacillus 属。

You can do some assertiveness training.

你可以进行一些自信训练。

We were well on the path to making a rear-wheel-drive global platform," says Mays."

我们正致力于建立一个后轮驱动的平台，"Mays这样说道。"