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Methods CDFI findings of 35 patients with B-CS were retrospectively analyzed and compared with the findings of venography of inferior vena cava.

回顾性分析35例B-CS的CDFI 检查结果,与下腔静脉造影结果对照。

Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

Results CT detectability of advanced gasˉtric carcinoma was100%.In92%the CT findings were consistent with operative and pathological findings.

结果 CT扫描对进展期胃癌的检出率 100%,手术所见与CT表现的符合率为92%。

Our findings demonstrate that in conjunction with clinical and radiographic findings, immunohistochemical evaluation with a panel of D2-40, EMA, brachyury, and GFAP is most useful in distinguishing chordoid meningioma from chordoid glioma, skeletal myxoid chondrosarcoma, extraskeletal myxoid chondrosarcoma, chordoma, low-grade chondrosarcoma, and enchondroma. A lack of strong, diffuse S100 reactivity may also be useful in excluding chordoid meningioma.

我们的结果表明,结合临床和影像学资料,D2-40、EMA、brachyury和GFAP这样一个免疫标记组合就能很好地鉴别脊索样脑膜瘤和脊索样胶质瘤、骨的黏液样软骨肉瘤、骨外的黏液样软骨肉瘤、脊索瘤、低级别软骨肉瘤、内生性软骨瘤。S100染色不强烈、不弥漫也有助于排除脊索样脑膜瘤的诊断。

The CC MRI findings are characterized mainly by:(1)frequently-encountered multiple circular foci during the cysticercus survival:small excentric spotty images of the mural cysticercus scolex :slightly high signs on T1WI and middle-lower signs on T2WI;lower signs on T1WI and high signs on T2WI of the capsular liquid;lower signs of the cerebrospinal fluid but relatively high signs of the capsular liquid on FLAIR;and unremarkable peripheral edema;(2)scolex disappearance,enlarged capsular cavity and remarkable peripheral edema during cysticercus degeneration and necrosis;(3)lower signs on T1WI and T2WI and peripheral edema disappearance after the focal calcification;(4)findings shown by the enhanced scanning:strengthened (24/36) or non-strengthened (12/36) cyst-wall circular images;strengthened (22/36) or non-strengthened (14/36) small intracapsular spotty images;(5)cerebral-ventricular type often occurring in the third and fourth ventricles:one case in the third ventricle (1/36) and three cases in the fourth ventricle (3/36),all of suffered from obstructive hydrocephalus;(6)hydrocephalus caused by arachnoid adhesion (2/36) in meningeal type.

结果 脑实质型18例,脑室型4例,脑膜型3例,混合型11例,主要MRI特点:(1)囊虫存活期,病灶呈圆型,多发常见,附壁囊虫头节呈偏心型小点状影,T1WI呈略高信号,T2WI呈中低信号;囊液T1WI呈低信号,T2WI呈高信号;在FLAIR上脑脊液呈低信号,而囊液呈相对高信号;周围水肿不明显。(2)囊虫退变坏死期,头节消失,囊腔扩大,周围水肿明显。(3)病灶钙化后,T1WI及T2WI均呈低信号,周围水肿消失。(4)增强扫描表现为:囊壁环状增强(24/36),或不增强(12/36);囊内小点状影增强(22/36),或不增强(14/36)。(5)脑室型:常发生于第三、四脑室,其中第三脑室1例(1/36),第四脑室3例(3/36),均引起阻塞性脑积水。(6)脑膜型:因蛛网膜粘连,而引起脑积水(2/36)。

Methods Uitrasonic findings of 68 cases with unilateral exophthalmos confirmed by surgical operation and CT findings were analyzed retrospectivley.

分析总结了临床经手术或CT确诊的单侧眼球突出68例超声检查结果。

"Our findings point to an as yet undefined cellular pathway that includes TBX15 and is involved in the control of body weight," Dr. Doria told Medscape."If these findings are confirmed in other populations, molecules in this pathway could become potential targets for new drugs, although these findings are still preliminary."

Doria博士向Medscape表示,我们的研究发现指出一个尚未定义的细胞路径,其中包含TBX15且和体重控制有关,若这些研究发现在其他研究中确认,此路径中的分子将成为新药的潜在目标,但这些发现尚属初步阶段。

"Our findings point to an as yet undefined cellular pathway that includes TBX15 and is involved in the control of body weight," Dr. Doria told Medscape."If these findings are confirmed in other populations, molecules in this pathway could become potential targets for new drugs, although these findings are still preliminary."

Doria博士向Medscape表示,我们的研究发现指出一个尚未定义的细胞路径,其中包含TBX15且和体重控制有关,若这些研究发现在其它研究中确认,此路径中的分子将成为新药的潜在目标,但这些发现尚属初步阶段。

Indications: gastrointestinal bleeding: n = 30 (16 positive findings: four ulcerative jejunitis, four polyps, two angiodysplasia, two blue rubber blebs, two Meckel's diverticula, one anastomotic ulcer, one reduplication); suspected Crohn's disease: n = 20 (11 had Crohn's disease); abdominal pain: n = 12 (six positive findings: three Crohn's disease, two lymphonodular hyperplasia, one blue rubber bleb); protein loss: n = 9; malabsorption: n = 12 (seven positive findings: six enteropathy, one ascaris).

适应症:胃肠道出血:n = 30(16例阳性结果:4例溃疡性空肠炎、4例息肉、2例血管发育不良、2例蓝色橡皮泡、2例麦克尔憩室、1例吻合处溃疡、1例增殖);可疑性克罗恩氏病:n = 20(11例克罗恩氏病);腹部疼痛:n = 12(6例阳性结果:3例克罗恩氏病、2例淋巴小结增生、1例蓝色橡皮泡);蛋白质丢失:n = 9(4例淋巴管扩张);吸收不良:n = 12(7例阳性结果:6例肠病、1例蛔虫)。

Objective To study the MR findings and its relationship with clinical manifestions of cerebral palsy caused by hypoxic-ischemic brain damage.The pathological mechanisms of MR findings were also explored.Methods The MR findings of14patients with cerebral palsy caused by hypoxic-ischemic damage were studied retrospectively and correlated with clinical findings.All those patients underwent MRI.Cerebral cortex and subcortical white matter,deep white matter,basal regions and thalami,and ventricles and subarachnoid space were observed on T1WI and T2WI.

目的 通过分析14例缺氧缺血性脑损伤所致脑瘫的MR成像特点及临床表现,讨论了该病的MRI表现与临床表现的相关性,以及MRI表现的病理损伤机制方法对14例缺氧缺血性脑损伤所致脑瘫患儿行MR检查,在T1WI及T2WI上对脑皮层及皮层下白质、深部白质、基底节、丘脑、以及脑室和蛛网膜下腔等部位进行观察。

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