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The proportions of Ⅰ~Ⅱgrade and Ⅲ grade were 73.8%、 83.1%; 45.7%、 65.2% between 92 samples of Urgur patients and 188 samples of han patients . Lymphy node metastasis in Uygur patients were greater than Han patients in Ⅰ~Ⅱgrade and Ⅲ grade (X~2=13.14, P.001; X~2=5.08, P.05).(3) The proportions of the expression of VEGF-AmRNA and its protein were 31.8%、 57.1%、64.3%, 27.3%、 53.6%、 59.5% in difference pathological grade in 92 samples, With increasing of the pathological grade,the VEGF-AmRNA and its protein expression are highly (X~2=6.26, P.05; X~2=6.21, P.05); The proportions of the positive expression of VEGF-AmRNA and its protein were 68.4
392例浸润性乳腺癌组织中VEGF-AmRNA和其蛋白的表达在不同组织学分级中其阳性率分别是31.8%、57.1%、64.3%,27.3%、53.6%、59.5%;二者在不同组织学分级中表达差异具有统计学意义(X~2=6.26,P.05;X~2=6.21,P.05);在淋巴结转移组与非转移组中VEGF-AmRNA和其蛋白的表达阳性率的分别是68.4%、31.49,61.4%、31.4%,在淋巴结转移组VEGF-AmRNA和蛋白的明显高于淋巴结未转移组(X~2=11.96,P.001;X~2=7.79,P.05);VEGF-AmRNA和其蛋白的表达
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Results The expression level of VEGF mRNA was lower in DMCI group than that of NDMCI group at every time point (P.05 ~ 0.01). The expression level of FLK1 mRNA was lower (P.01) at 12 h after MACO in DMCI group than that in NDMCI group. Except for at 6 h, there was no significant difference between DMCI and NDMCI group in the expression level of FLT1 mRNA.
结果 DMCI组在脑缺血后各时间点脑缺血半暗带等值区VEGF mRNA的表达水平均显著低于NDMCI组(P.05~0.01),FLK1 mRNA 表达水平在脑缺血后12 h显著低于NDMCI组(P.01),FLT1 mRNA 表达水平在脑缺血后各时间点(除6 h)与NDMCI组差异无统计学意义。
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The mice were used as experimental animals in this study,through the experiment in vitro and in vivo,systemic invested the dynamic changes in expression and localization of FGF7,FGF10 and its receptor in mammals development,lactation and involution;revealed the relationships between the expression of FGF7,FGF10 and its receptor and the function;clarified the function of FGF7 and FGF10 in mammary gland development,lactation and involution,and the effect of mammogenic hormones on expression of FGF7 and FGF-10 and its receptor in different periods in vitro.
本研究主要以小鼠为实验材料,通过体外和体内实验,系统研究FGF7、FGF10及KGFR在哺乳动物乳腺发育、泌乳及退化过程中表达定位的动态变化,揭示FGF7、FGF10及KGFR表达变化与乳腺发育及泌乳功能间的对应关系,阐明FGF7、FGF10在乳腺发育、泌乳及退化过程中的功能以及乳腺发育激素对不同时期乳腺FGF7、FGF10及KGFR表达的影响。
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Objective The expression of iNOS bFGF CyclinD1 erbB-2 were studied by immunohistochemistry to investigate the relationships between the expression of iNOS and proliferative index of breast carcinoma such as bFGF CyclinD1 and erbB-2.The relationship between expression of iNOS and ages menstruous status tumor size histological stage TNM stage venous invasion ER PR lymph-node metastasis distant metastasis and survival rate in 5 years.
目的 研究诱导型一氧化氮合酶(Inducible Nitric Oxide,iNOS)在乳腺癌中的表达及与乳腺癌增殖指标碱性成纤维细胞生长因子、细胞周期素D_1(CyclinD_1)、癌蛋白(erbB-2)的关系,同时研究iNOS与年龄、月经状况、肿瘤大小、肿瘤学分级、TNM分期、脉管侵袭、ER、PR、淋巴结转移、远处转移、预后的关系。
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The prtein autophosphorylation assay showed that ZmCIPK31 possessed protein kinase properties and millimolar range of Mn2+ was effective cofactor.3. Expression analysis of ZmCIPK31 gene in maizeCertain ZmCIPK31 expression level in stem, root, embryo, filament, seed and leaf of maize were detected under normal growth conditions. And the relative expression level is the highest in filament.
蛋白自磷酸化试验表明ZmCIPK31具有激酶活性,且微量的Mn2+是有效的辅助因子。3、ZmCIPK31基因在玉米中的表达分析ZmCIPK31在正常生长条件的玉米的茎、根、幼胚、花丝、种子及叶中均有一定量的基础表达,且在花丝中的相对表达量最大。
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Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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Results: The expression of CTGF protein and CTGF mRNA in the nomal and sham operation group is low in the intracytoplasm of Mesangial cells, renaltubular epithelial cells and renal interstitial cells. Compare with sham operation group, the expression of CTGF protein and CTGF mRNA as yellow particulate in the mode group was markedly increased, and the fibrosis of nephridial tissue is obvious. Panaxnotoginseng could significantly decrease the expression of CTGF protein and CTGF mRNA(P.05), and there was no significant difference between Panaxnotoginseng treatment group and Benazepril treatment group.
结果:正常组及假手术组肾小球系膜细胞、肾小管上皮细胞以及肾间质细胞胞浆内有少量CTGF蛋白及其mRNA的黄色颗粒状阳性反应物,模型组上述部位的CTGF蛋白及其mRNA呈强阳性表达,三七总皂苷组上述指标表达较模型组显著减少,有统计学差异(P.05),与阳性药物组比较差异不显著。
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Daidzein can induce expression of VTG mRNA inserum-free medium in vitro, and has co-effect on expression of VTG mRNA with differentconcentration of E_2, which might be related with the up-regulation of the gene expression ofERβ.
在低雌激素背景下,一定剂量的大豆黄酮能促进VTG mRNA的表达;而在高雌激素背景下,大豆黄酮对VTG mRNA的表达具有拮抗效应,且大豆黄酮可能通过ERβ调节VTG基因的表达。
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Objective To investigate the interrelationship between the expression of VEGF and the oncosis of neuron after ICH by establishing the rat ICH model through the expression of oncosis of neuron after ICH and the cell location of VEGF-positive cells in perihematoma and the expression of VEGF. Methods The rat ICH model was induced by two-step.
目的 通过建立大鼠脑出血动物模型观察血管内皮生长因子在出血灶周的细胞定位和动态表达变化和脑出血后神经细胞胀亡时程表达以探讨两者之间的相关性。
- 相关中文对照歌词
- Tată (Father - Romanian Version)
- Te-Am Visat
- Without Expression
- Tu Şi Eu
- Man With No Expression
- În Culori
- Last Night
- Last Night
- Tears To Tell
- Fairplay
- 推荐网络例句
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In the days of sailing vessels the crew were afraid they would be becalmed on the ocean.
在使用帆船的时代,船员们担心他们会因为无风而无法在海洋上航行。
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As long as foreign donors pay the PA's salary bill, few expect a new intifada.
只要外国继续为巴权力机构的薪水买单,希望发动新暴动的人便寥寥无几。
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Speak with contempt of none,form slave to king,the meanest bee,and will use,a sting.
别用 言词贬低任何人,无论国王还是奴隶。最卑戝的蜜蜂也会用它的毒针蜇人。