查询词典 fibrosis

The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups（P＜0.01）.The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group（P＜0.01,P＜0.05）.The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面，差异均有显著性（P＜0.01）；IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性（P＜0.01）； MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达，差异具有显著性（P＜0.01，P＜0.05），MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达；TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

This process is also reactivated in a variety of diseases including fibrosis and in the progression of carcinoma .

近来发现，这一过程和许多疾病存在联系，包括各种纤维化疾病及恶性肿瘤的发生，发展。

Ample evidence that fibrosis regresses with control of hepatitis B, hepatitis C, or other chronic liver diseases[2] attests to the tremendous regenerative power of the liver, and the rapid progress made in the development of targeted antiviral and disease-specific treatments.

在乙肝、丙肝和其它慢性肝病得到控制以后，纤维化是可以逆转，这方面已经得到了足够的证据证明肝脏巨大的再生能力以及在靶定抗病毒和疾病特异性治疗上所获得的快速好转。

ECM remodelling and fibrosis regulated by MMPs are believed to be important contributors to the progression of heart failure.

一些研究表明，MMP-1和TIMP-1对心脏重构和心力衰竭具有重要作用。

Keratin mutation predisposes to mouse liver fibrosis and unmasks differential effects of the carbon tetrachloride and thioacetamide models.

角蛋白突变诱发小鼠肝脏纤维化，揭示四氯化碳和硫代乙酰胺模型的的差别效应

Objective To study the effect of Fuzhengruanjian prescriptions on pulmonary fibrosis in rats and its possible mechanism.

目的 研究扶正软坚方对肺纤维化的干预作用及对MMP-9和TIMP-1表达的影响。

There was no statistical significance, between the groups of patients assigned to receive either type of interferon when fibrosis score, age and genotype were matched.

经纤维化评分、年龄和基因型配对后，两组接受不同干扰素治疗的患者无组间统计学显著差异。

2Radiofrequency ablation with anchor-shaped electrodes could induce coagulation necrosis of most of the VX2 nodules in rabbit lung, and could induce apoptosis of tumor cells; The course of pathological changes of ablated area was surrounded by organization, the ablated area would be encapsulated by fibrosis tissue.

2采用锚状电极RFA治疗兔肺内VX2肿瘤，其基本病理改变为：绝大多数肿瘤病灶的凝固性坏死，进一步的改变为凝固性坏死区被机化包裹，可有钙盐沉积；RFA可诱导肿瘤细胞凋亡。

Color Doppler ultrasonography was performed to avoid the injure of the blood vessel and bile duct during the procedure, the biopsy specimens were stained with routine hematoxylin and eosin or special dyed method for fibrosis such as Masson trichrome.

在超声引导下使用自动活检枪弹射18G配枪用槽式切割活检针，彩超引导避开肝内血管及胆管、胆囊等重要结构，肝组织标本采用HE染色及马松染色。

Microscopically, extrahepatic biliary atresia leads to this appearance in the liver, with numerous brown-green bile plugs, bile duct proliferation, and extensive fibrosis.

显微镜下所示肝外胆管阻塞引起肝脏此种病变，有大量的棕绿色胆栓，小胆管增生、广泛的纤维化。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐