查询词典 fibroblasts

Objective To study the effect of Danxuan Koukang drug serum on proliferation and proliferating cell nuclear antigen production of human oral mucosal fibroblasts induced by areca nut extract.

：目的观察丹玄口康对槟榔提取液(Areca Nut Extract，ANE)诱导的人口腔黏膜成纤维细胞(Fibroblasts， FB)的增殖及增殖细胞核抗原(Proliferating cell nuclear antigen，PCNA)表达的影响。

Objective To investigate the effects of epigallocatechin gallate and baicalin on human skin fibroblasts from ultraviolet radiation. Methods Fibroblasts were obtained and cultured from human skin.

目的：研究中药活性成分茶多酚单体没食子儿茶素没食子酸酯、黄芩苷对紫外线辐射损伤的成纤维细胞形态、增殖活性及产生IL-6、TNF-α的影响，探讨其光保护作用。

Adult male foreskin subcutaneous tissues apart from epidermis and hypodermis were taken by surgery operation and human foreskin fibroblasts were isolated and cultured, then enhanced green fluorescence protein in human fibroblasts were expressed by lipofectamine and lentiviral vectors, respectively.

取成年男性包皮皮肤的皮下组织，分离培养人皮肤成纤维细胞，分别采用脂质体和慢病毒载体介导转染人皮肤成纤维细胞表达绿色荧光蛋白。

Objective: To Compare the differences in the level of proliferation and apoptosis in keloid fibroblasts and normal skin fibroblasts.

目的：比较瘢痕疙瘩成纤维细胞与正常皮肤成纤维细胞在增殖－凋亡方面的差异。

There is growing evidence that human periodontal ligament fibroblasts are involved in this process.

越来越多的证据表明人牙周膜成纤维细胞(Human periodontal ligament fibroblasts， HPLF)在此过程中发挥了重要作用。

In order to investigate the inhibitory effect of salvia miltiorrhiza and tetramethyl pyrazine on scartricial fibroblast, the hypertrophic scar tissue of chest was chosen for culture of fibroblasts, and the influence of SM and TP on fibroblasts was observed, The effect of the drugs on the growth of fibroblasts, on DNA synthesis of fibroblasts and on mitosis index of fibroblasts were all determined quantitatively.

摘 要 增生性瘢痕是临床治疗难题之一，目前尚无有效的治疗方法。为了探讨丹参和川芎嗪对瘢痕成纤维细胞的抑制作用，取12例患者胸部增生性瘢痕组织，通过体外成纤维细胞培养，探讨不同药物浓度、不同作用时间对成纤维细胞生长的影响。

Results:Expression of elastase mRNA has been found in the endothelial cells,the medial smooth muscle cells and the adventitial fibroblasts of the abdominal aorta,the lymphocytes,monocytes in blood,the tracheal hyaline cartilaginous cells,the glandular cells of the pancreas,the epithelial cells of the parotid gland and submaxillary gland,the hepatoeytes,the endothelial cells of the liver sinusoid wall,the goblet cells of the mucous membrane of the small intestine,the cardiac myocytes,the renal interstitial fibroblasts,the alveolar epithelial cells,the cerebral glial cells,the fibroblasts of the dermis oorium of the skin,the primary spermaocytes,the secondary spermaocytes and sperm in the seminfferous tubule of the testis,the lymphocytes in the spleen and thymus.

结果正常大鼠腹主动脉的内皮细胞、中膜平滑肌细胞以及血管外膜成纤维细胞，血液细胞中的淋巴细胞、单核细胞，气管透明软骨细胞，胰腺的腺细胞、腮腺、颔下腺上皮细胞，肝细胞、肝窦壁的内皮细胞，小肠黏膜杯状细胞，心肌细胞，肾间质的纤维母细胞，肺泡上皮细胞，大脑胶质细胞，皮肤真皮纤维母细胞，睾丸曲精细管内的初级精母细胞、次级精母细胞以及精子，脾脏以及胸腺的淋巴细胞等，均有弹力蛋白酶mRNA的表达。

Probucol inhibited cholesterol efflux from normal human skin fibroblasts but not from fibroblasts from a Tangier patient.

普罗布考抑制正常人皮成纤维细胞的胆固醇释放，但不抑制丹吉尔患者的成纤维细胞的胆固醇释放。

By the cooperation of 8-MOP/UVA, the photoaging-characteristic biological markers of the dermic fibroblasts in vivo and in intro were changed as follows:① with a permanent switch of mitotic to stably postmitotic phentypes, fibroblasts displayed growth suppression and morphological changes of cell senescence;② increasing expression of SA-β-galactosidase;③ increasing expression of p16 protein;④ continuous up-regulation of mRNA of MMP-1 and MMP-3, while the protein of TIMP-1 was only slightly induced;⑤ high levels of the 4977bp deleted mtDNA accumulated in dermis and cultured fibroblasts, and large accumulation of a A→C base transversion of 414 position of 〓 of human mtDNA control region for replication of cultured fibroblasts also.

2.8-MOP/UVA作用下，体内外真皮成纤维细胞生物学特性出现具有光老化特征性的改变：①细胞由具有分裂活性的分裂表型转化为不具有分裂能力的分裂后表型，形态学出现细胞衰老的相应改变；②SA-β-Gal表达增加；③p16蛋白表达增加；④MMP-1、MMP-3 mRNA持续表达而TIMP蛋白表达仅被轻微诱导；⑤mtDNA 4977bp缺失大量累积，培养成纤维细胞mtDNA复制控制区〓片段414碱基迅速出现大量A→C的点突变。

Results The results showed that fibroblasts were the main source of extracellular matrix production in bile duct wall. The phenotype of fibroblasts in inflammatory strictured bile duct wall changed obviously, quiescent fibroblasts were activated and transformed to myofibroblasts, with massive proliferation.

结果 成纤维细胞是胆管壁中合成胶原的主要细胞；炎性狭窄胆管壁的纤维化增厚明显，其成纤维细胞表型改变，由相对静止转化为功能活跃状态，并进一步向肌成纤维细胞转化，且大量增殖。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。