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And the overgrowth lesions are characterized by epithelial acanthosis, with long, branched rete peg formation, and the excessive accumulation of radiating collagen fibers in the connective tissue layer.

此种疾病在组织学上的特徵为：上皮细胞层数有增厚的发现，并呈现明显的棘状凸出延伸至结缔组织中，在结缔组织中则有大量胶原蛋白堆积而产生纤维化；然而引发牙龈增生的病理机制至今仍不明确。

Fufangbiejia Formula can inhibit obviously the accrementition of collagen fibers in rats with idiopathic pulmonary fibrosis.

结论复方鳖甲方有明显抑制实验大鼠IPF胶原纤维增生的作用。

The result of Picric- sirius red polarized light method shows thatthe accrementition and reconstitution of mesenchymal fibers were markedly in experimental group compared with control group, especially in plantaris.Ⅰ-type collagen dominates in mesenchymal, IOD ratio ofⅠ/Ⅲchanged.

5天狼猩红-偏振光法提示在实验组骨骼肌间质纤维结缔组织明显增多尤其是在跖肌，以Ⅰ和Ⅲ型胶原增生为主，Ⅰ型胶原增生更为明显，Ⅰ型胶原与Ⅲ型胶原比值增高。

The up-regulation of the expression of MMP-9 perhaps takes part in the accrementition and reconstitution of mesenchymal fibers (Ⅰ-type collagen dominates in mesenchymal, IOD ratio ofⅠ/Ⅲchanged). MMP-9 can facilitate inflammatory cell infiltration, aggravate the development of CAM.

2MMP-9的增高可能参与了骨骼肌间质纤维增生及其构成的改变(Ⅰ和Ⅲ型增多，Ⅰ型胶原与Ⅲ型胶原比值增高)，诱导炎性细胞浸润，加重慢性酒精中毒性肌病的发生发展。

Gelatin zymography was used to detect the activation and secretion of MMP-2 and MMP-9 in gastroenemius、soleus、plantaris during early、intermediate and final stage of experimental group. Picric- sirius red polarized light was used to detect the accrementition and reconstitution of mesenchymal fibers in the muscle specimens from the operated group and normal controls.

3采用RT-PCR和Western blot及免疫组化的方法分别检测不同时期的大鼠骨骼肌中核因子κB、MMP-2、MMP-9的表达；采用明胶酶谱的方法检测实验组大鼠早、中、晚期腓肠肌、比目鱼肌、跖肌MMP-2、MMP-9活化、分泌情况；天狼猩红-偏振光法检测大鼠骨骼肌间质纤维增生及成分改变。

3FNS could ameliorate the auricular reconstruction of experimental AF dogs, lessen the ultrastructural demolishing of atria sinistrum cells, and inhibite the accrementition of collagen fibers in the myocardium tissue of atria sinistrum.

3小脑顶核仿生电刺激可改善实验性房颤犬心房的重构；可减轻实验性房颤犬左房心肌细胞超微结构的破坏；可减轻实验性房颤犬左房心肌组织中胶原纤维的增生。

Acetalization increased the tensile strength and density of fibers.

实验表明强度和密度最大值的共混比为(10%～20%)/(90%～80%)。

Antibodies against col Ⅲ reacted strongly in the entire pterygial stroma. Conclusions Components of ECM are changed in the pterygium: the sub-epithelial connective tissues and vessels are more prominent in the pterygia than in normal conjunctiva tissues, and abnormal fibers are visible only in the deeper subepithelial connective tissues. This study documents the overexpression of LN and col Ⅲ. They may play roles in cellular adherency, migration and angiogenesis. Also this study documents the overexpression of MMP3 which may degrade ECM in the pathogenesis of the pterygium.

结论翼状胬肉组织中ECM的成分较正常球结膜发生改变，有大量的弹性纤维变性、胶原纤维增生及新生血管形成；col Ⅲ在翼状胬肉组织中表达增加，LN及胶原纤维可能对翼状胬肉中血管形成、细胞粘附和迁移及ECM重建起作用；MMP-3在翼状胬肉组织中表达增加，其对ECM成分的降解作用可能有助于翼状胬肉的形成和向角膜中央侵袭。

Distribution of cannabinoid receptor 1 (CB1) and2 (CB2) on sensory nerve fibers and adnexal structures in human skin .

大麻素II型受体(CB2)在人皮肤及皮肤恶性肿瘤的组织分布。

objective:to observe the distribution of adrenergic fibers in adult cardiac conduction system.

目的：观察成人心脏传导系统中肾上腺素能神经纤维的分布。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。