查询词典 exotoxins

Objective To evaluate the toxic effects of staphylococcus aureus exotoxins and neutrophils on retinal pigment epithelium cells.

目的 观察金黄色葡萄球菌外毒素及中性粒细胞对视网膜色素上皮细胞的毒性作用。

Furin is also involved in many diseases such as the activation of viral glycoproteins and bacterial exotoxins and the metastasis of cancer.

多肽或蛋白质以前体形式合成后，需要前体加工酶的剪切加工才能获得完全的生物活性。

Furin is also involved in many diseases such as the activation of viral glycoproteins and bacterial exotoxins and the metastasis of cancer.

中文摘要多肽或蛋白质以前体形式合成后，需要前体加工酶的剪切加工才能获得完全的生物活性。

Both staphylococcus aureus exotoxins and neutrophils can damage the RPEC by inducing necrosis, and their function had synergetic effect.

金黄色葡萄球菌外毒素对RPE细胞具有毒性作用，其机制主要以细胞坏死的方式进行。

Design of peptide inhibitors for furin based on the C-terminal fragment of histone H1.2The mammalian proprotein convertase furin has been found to play an important role in diverse physiological and pathological events,such as the activation of viral glycoproteins and bacterial exotoxins.

基于组蛋白H1-2片段的furin抑制剂的设计改造在哺乳动物的许多生理和病理活动中，前体加工酶furin起到了非常重要的作用，例如对病毒糖蛋白和细菌毒素的激活。

The skin of atopic dermatitis patients exhibits a striking susceptibility to colonization and infection with Staphylococcus aureus, which can secrete various exotoxins including staphylococcal enterotoxin B being the most common.

过去文献显示，高达95%的异位性皮肤炎患者的皮肤上有金黄色葡萄球菌的增生与感染。

Highly active, small-molecule furin inhibitors are attractive drug candidates to fend off bacterial exotoxins and viral infection. Based on the 22-residue, active Lys fragment of the mung bean trypsin inhibitor, a series of furin inhibitors were designed and synthesized, and their inhibitory activity toward furin and kexin was evaluated using enzyme kinetic analysis. The most potent inhibitor, containing 16 amino acid residues with a Ki value of 2.45×10~(-9) M for furin and of 5.60×10~(-7) M for kexin, was designed by three incremental approaches.

本论文研究活性多肽类似物的设计、制备和功能，分为四个部分，采用多肽固相和液相合成的方法，分别合成了活性多肽绿豆胰蛋白酶抑制剂Lys片段长链16肽、天花粉胰蛋白酶抑制剂、癌胚抗原肽、甜味肽等一系列类似物，并测定了这些类似物的生物活性，有以下新的研究结果：1、furin酶抑制剂的设计、制备和功能；2、芳香氨基酸芳环之间的π-π共轭能部分补偿二硫键的作用；3、癌胚抗原肽Gly4被L-Pro替代可增加与HLA-A2分子的结合；4、肽键对甜味肽保持甜味是必须的。

These exotoxins are superantigens.

此菌会分泌许多外毒素，其中，以金黄色葡萄球菌肠毒素B为异位性皮肤炎患者皮肤上最常见的金黄色葡萄球菌外毒素。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。