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These data suggest that in response to smoke exposure, TNF-alpha-mediated down-regulation of PGC-1alpha may be a key step leading to vascular and myocyte dysfunction, effects that are more evident in oxidative than glycolytic skeletal muscles.

这些数据表明，响应吸烟暴露，肿瘤坏死因子-α介导的PGC-1α下调可能是导致血管和心肌功能障碍的关键一步，这种作用在氧化型肌肉比在糖酵解骨骼肌更明显。

Putting in comparison the life of this leading novels author, J. R. R Tolkien along with the milieu of the creation of the trilogy as well as its plots and the characterization and the counterparts of Gothic novels, we can find evident similarities between them and the plain impact on the novel from Gothicism. It is within the framework of Gothicism that the novel presents the persistent religious issues and technophobia that most Gothic novels lay bare.

通过对小说原著作者托尔金的生活背景，以及小说的创作背景和小说中情节和人物的分析，可以看出指环王系列小说的创作背景与哥特小说的背景有明显的相似处，而小说本身也受到传统哥特风格的影响，并且在这个风格框架下，小说继续体现了典型的哥特小说中的宗教问题和对现代技术的恐惧。

Under this condition, the Gouda water station will be reaccepted by consumer self-evident, and the market prospect is unprecedented.

在这种大环境的影响下，智能水站不言而喻、受到消费者的青睐，市场前景空前。

It is most evident in midtones and highlights, and it imparts a subtle graininess to the image overall.

这和其他DLP机器没有区别。最明显的是在中间过渡色调和高亮部分。

Hair like graining is also evident in some of them.

头发像木纹也很明显，在其中的一些。

It is evident through the graining and twining.

这是显而易见的，通过木纹和唐宁。

Grotius makes it evident, not so much in words as in the method of exposition, that he is opposed to a higher interpretation.

格罗提斯使得显而易见的，没有这麼多的词的方法的论述，他反对向更高解释。

Like Isuzu, you may have grown tired of all the Wild West hagiography evident in so many sport-ute names.

和五十铃一样，你也同样会厌倦于大多数运动型小货车的名字，它们千篇一律取材于关于西部荒莽的各种典故）。

Or create an army of genetically engineered brutes to do their bidding: Various hair-raising possibilities are self-evident.

肆无忌惮的独裁者能够克隆一个受他摆布的阶级，或者创建一支野蛮的、惟命是从的遗传工程部队。

Nowadays with fierce market competition, the importance of franchising strategy for the development of hairdressing enterprises become more and more evident.

在当今激烈的市场竞争中，特许经营战略对于美发企业发展的重要性日益凸现出来。

You can do some assertiveness training.

你可以进行一些自信训练。

We were well on the path to making a rear-wheel-drive global platform," says Mays."

我们正致力于建立一个后轮驱动的平台，"Mays这样说道。"