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The ET and NO produced locally in renal play more important role in the development of proteinuria.

在蛋白尿发生发展过程中血浆和肾皮质ET、NO均有显著改变,而肾皮质ET、NO含量的改变在蛋白尿的发生发展中起重要作用。

Salpingectomy has no obvious effect on the outcome of IVF-ET and baseline endocrine within a period of time, but it reduces the ovarian response to superovulation on ipsilateral ovary in IVF-ET.

输卵管切除术对IVF-ET周期妊娠结局无显著影响,在一定时间内不引起患者基础内分泌的改变,但降低手术侧卵巢的反应性。

The patients were divided into four groups. Group A included 48 women with previous unilateral salpingectomy. Group B included 41 patients with previous bilateral salpingectomy. Group C included 50 patients with obstruction of fallopian tube while group D included 40 patients with hydrosalpinx (without surgical procedure before). The ovarian responses to superovulation and the outcomes of IVF-ET were evaluated.

选择2006年2月至2007年6月在本中心行常规IVF-ET治疗的179例不孕患者为研究对象,共分为A、B、C、D四组,A组为48例单侧输卵管切除患者,B组为41例双侧输卵管切除患者,对照C组为50例双侧输卵管阻塞患者,对照D组为40例单侧或双侧输卵管积水患者,比较4组患者在IVF-ET周期中卵巢对控制性超排卵的反应及其结局的差异。

In the end, a comparison was made to detect 24 hours TUP ,renal function parameter, changes of NO and ET-1 contents , nephridial tissue examination. Results: 1、Compared with Normal Control group , NO contents decreases in Model Control(P〈0.05),but the ET-1 contents increased.

治疗4周后比较情各组情况,检测24小时尿蛋白总量和肾功能指标及血清NO、ET-1的变化,并进行肾组织学检查。

Objective: To investigate the expression of endothelin-lET-1) mRNA in the villus of pre-eclampsia and the relationship between the ET-1 and pre-eclampsia.

目的:研究重度妊娠高血压综合征患者胎盘绒毛组织中内皮素-1(ET-1)mRNA的表达,探讨ET-1与妊高征的关系。

The reason Manshen NO.1 prescription can restrain accrementition in intercapillary cells and mesangial region may be due to its adjustment of NO and ET-1's contents in vivo. It is worth of doing further researchs in the future.

1、慢肾1号方对系膜增生性肾炎有良好的治疗作用,改善症状,抑制系膜细胞及基质区的增生,从而阻止肾小管硬化的发展,防止肾功能衰竭的发生,2、肾慢1号方能够提高模型组小鼠血清NO的含量,降低ET-1的含量,使之恢复正常。3、慢肾1号方可能是通过调节体内细胞因子(NO及ET-1)的含量,从而达到抑制系膜细胞及基质增生的目的,值得深入研究。

ET-1 was negatively related to NO and lung function(FEV1/FVC,MMEF,FEV25/H and SpO2),(r=-0.55,-0.51,-0.48,-0.53,all P<0.05).Conclusion ET-1 and NO would be play an important role in the pathogenic process of asthmatoid chronic bronchitis.

ET-1和NO参与慢性支气管炎的发病过程,它们的水平变化可能反映了病情的严重程度,可望作为判定治疗效果的指标。

The effects of ET on bronchomotor tone may be modified by NO as this is a bronchomotor, and the imbalance between ET and NO may play an important role in asthma pathogenesis.

气道ET-1和NO平衡失调是引起哮喘发生的机制之一。

Because of the epithelioid cells and endotheliocyte being injured seriously in the chronic cor pulmonale,there was not enough NO to antagonize the ET-1,but the content of blood NO remain normal.

NO含量不高,可能是肺心病长期慢性肺部疾病上皮细胞和内皮细胞受损严重,已不能产生足够的NO来拮抗ET-1,持续高ET-1在肺心病的病理生理过程中起重要作用。

Methods The data of 242 cycles of IVF-ET which were accomplished in the Reproductive Medicine Center of 204 hospital during March 2007 and March 2009 with a history of hydrosalpinx were analyzed retrospectively.The data were divided into four groups,A group included 57 cycles:a proximal tubal ligation with distal tubal salingostomy had been introduced to the patients before the IVF.

回顾性分析2007年3月至2009年3月在沈阳204医院生殖中心因输卵管性不孕接受IVF-ET治疗共242周期的临床资料,根据IVF-ET前输卵管情况分4组,A组:57个周期,采用输卵管近端结扎伞端造口术;B组:55个周期,已行输卵管切除术;C组:52个周期,积水未行手术组;D组:78个周期,单纯输卵管阻塞,作为对照组。

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