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The results showed that the contents of glutamic-pyruvic transaminase and glutamic oxaloacetic transaminase in part of the dogs were high and spontaneous pathologic changes occurred in the important organs, such as lung, kidney and brain. The incidences of interstitial pneumonia, cerebral ependymitis and vascular infiltration were high. Cloudy swelling and vasular degeneration appeared in part of hepatocytes and epithelial cells of renal tubules.

实验结果为部分犬的肝功能谷丙转氨酶和谷草转氨酶偏高；肝、肺、肾和大脑等重要脏器有自发性病理改变；肺的间质性肺炎和大脑室管膜炎及血管围管性浸润发生率较高，部分肝细胞和肾小管上皮细胞呈现浊肿或空泡变等。

Some evidence is presented showing that epididymosomes are secreted in an apocrine manner by the epididymal epithelial cells.

有证据表明epididymosomes是附睾上皮细胞通过顶分泌的形式分泌到管腔中。

Hyaline and erythrocytic casts, glycogen deposition in tublar epithelial cells, and renal interstitial fibrosis also were observed in model rats.

肾小管上皮细胞内有糖原沉积，肾小管蛋白管型和红细胞管型，肾间质纤维化，伴发间质脓肿形成。

Mucous membrane protective screen is formed by the join between cell of alvine mucous membrane and cell, atrophy of cell of alvine mucous membrane, wither dies, cellular connective can send alvine path to connect flabbily appear a gender to increase, provide passageway; chemical protective screen for the bacterium inside bowel and toxin the digestive juice that shows epithelial excretive mucus and alvine memory are in bowel and digest enzymatic the chemistry that waits for material to reach its to develop.

黏膜屏障由肠黏膜细胞和细胞间的连接构成，肠黏膜细胞萎缩、凋亡、细胞连接的松弛可致肠道通透性增加，为肠内细菌及毒素提供通道；化学屏障指肠上皮细胞分泌的黏液及肠内存在的消化液和消化酶等物质及其发挥的化学功能。

Meanwhile the lung tissue slide was prepared for electron microscopic observation at 180 minutes after reperfusion.Result: HO-1 expression was upregulated in two groups in the pulmonary endothelial cells,part of pulmonary vascular smooth muscle cells,extima of vessels and epithelial cells of airway,the absorbance was 0.148±0.013,0.158±0.012,respectively.The Shenmai injection group showed higher absorbance than those of the IRI group( P .01),lower W/D and IAR values than those of the IRI group( P .01) significantly and lighter abnormal changes of the lung tissue in morphologically than those of the PIRI group.

结果：HO-1在I-R组、SM组肺血管内皮、部分血管平滑肌、外膜层及部分气道上皮均有阳性表达，原位杂交的平均吸光度分别为0.148±0.013，0.158±0.012，SM组HO-1的表达水平明显高于I-R组( P 。01)，W/D，IAR值显著低于I-R组( P 。01)，肺组织形态学异常改变轻于I-R组。

Immunohistochemical staining was observed in the murine cornea1 epithelial cells, retinal and extraocular muscles.

正常小鼠眼部有PIM3基因及蛋白水平的表达，提示PIM3可能在眼部具有一定的功能。

As a facultatively intracellular pathogen,NTHI has the potential to penetrate and survive in alveolar epithelial cells.

BEAS-2B细胞在NTHI刺激后IL-8分泌增加，可部分被两种MAPK抑制剂所抑制。

PART 2:The molecular mechanisms of Nontypeable Haemophilus influenzae induced inflammatory response in respiratory epithelial cells Objective:Nontypeable Haemophilus influenzaewas traditionally considered as an extracellular pathogen in respiratory infections.In this study,we established a model of infected cells to confirm NTHI was also a facultatively intracellular pathogen.Mitogen activated protein kinasesare the important signal transduction pathway in mediating inflammatory response induced by NTHI in respiratory epithelium.In this study,we elucidate the impact of NTHI,and its SCF and EP on the expression of MAPK and subsequent proinflammatory mediators.

第二部分：NTHI致呼吸道上皮细胞炎症反应的分子机制研究目的：通过建立呼吸道上皮细胞株的体外NTHI感染模型，确认NTHI在细胞内的存活，观察NTHI及其组分(可溶性胞质成分SCF、外膜蛋白EP)对呼吸道上皮细胞MAPK信号传导通路和后续的前炎症因子表达的影响，并应用特异性ERK-MAPK抑制剂U0126、p38 MAPK抑制剂SB203580特异性阻断下游MAPK信号传导通路，观察它们对呼吸道上皮细胞分泌前炎症因子表达的影响。

The follicular epithelial cells of thyroid gland were just a few and scattered irregularly, follicular cavity was big. The numbers of TSH cell and C cell reduced, but the numbers of ACTH rose, fasciculate zone of adrenal gland broadened obviously.

模型组甲状腺滤泡上皮细胞明显稀疏，分布不规则，滤泡腔直径较大，TSH细胞、C细胞数下降，ACTH细胞数明显上升，肾上腺束状带明显增宽。

These findings suggest that epithelial cells play an important role in promoting ALPase expression in pulp fibroblastic cells.

综上所述，上皮细胞在提高牙髓成纤维细胞ALPase表达方面起到重要的作用。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。