查询词典 endosome

AIM: To develop a multi-component DNA delivery system which incorporated hepatocyte targeting ligand, DNA compressing domain and endosome disruptive molecule in one complex.

目的：研制含有靶向配基、DNA聚合亚基、溶酶体活性成分及聚乙二醇等多种组分的肝靶向的DNA给药系统。

Next, seven of those trimmed molecules combine to form a ring-shaped structure, or heptamer, that captures the two factors and is transported to an internal membrane-bound compartment called an endosome.

之后，七个剪裁过的保护抗原分子会聚集起来，形成一个环状构造，称为「七聚体」，藉此抓住另外两种因子，再一起送入细胞内一个称为「内小体」的膜状构造。

The internalized sgc8 aptamers are located inside the endosome. This study indicates that sgc8 is a promising agent for cell-type specific intracellular delivery.

Sgc8进入胞内后定位在内涵体中，Sgc8的内吞性质与其靶蛋白PTK7的内吞性质相关。sgc8有望成为一种靶向T型淋巴白血病细胞的新型输送载体。

First, by colocalizing H-GNRs in different cellular organelles depicted by the respective markers, we demonstrate that H-GNRs colocalize with the endosome and lysosome but not with the Golgi apparatus.

文章的新意在于利用内源性荧光标记不同亚细胞器，运用单分子荧光技术定量探索金纳米棒在乳腺癌活细胞不同亚细胞器的分布和动力学。

Ecent researches have been strongly supported that Rab5a mainly regulated the fusion of early endosome and controlled the formation of vesicles on the plasma membrane and the downstream delivery of internalized molecules to a number of cellular locations.

ab5a是早期胞吞途径中一个重要的限速成分，主要负责调控胞吞中胞吞泡与早期内体的融合。

The protein is then transported by specialized cesicles to a late endosome that later matures into a lysosome . The mannose 6-phosphate receptor recycles back to the Golgi for re-use .

溶酶体蛋白质即由特异的囊泡运输到后内吞体中，最终形成溶酶体。6-磷酸甘露糖受体回到高尔基体上重新使用。

Thus,CMG-KALA nanoparticles have great potential as gene vectors for transfection in vitro.2.GS-peptide nanoparticles were synthesized as previous reported method in order to improve the ability of cell penetrating,endosome escaping and nuclear targeting.

通过激光共聚焦、荧光光谱以及红外光谱证明KALA可以成功地连接到CMG纳米颗粒表面；通过静电引力吸附将DNA与CMG-KALA纳米颗粒进行复合，并通过琼脂糖凝胶电泳证明该纳米颗粒对DNA具有很好的保护作用。

In macrophages, Legionella destructed the transmission of small bubble, prevented phagosome-lysosome fusion, prevented the meaning of the sterilization of endosome and lysosome, established its own unique copy of the body and swallowed up full of host cells, finally leaded to the host cell death.

在巨噬细胞内，军团菌破坏小泡传输，产生空泡，阻止吞噬体-溶酶体融合，阻止内涵体和溶酶体的杀菌作用，建立其独占的复制型吞噬体，以二***复制，产生大量的吞噬体，布满宿主细胞，导致宿主细胞死亡。

In eukaryotic cells,Toll-like receptors in endosomal membrane were show to recognize viral RNA in endosome and thereby initiate innate immunity pathways for virus resistance.By contrast,a cytosolic RNA receptor protein, RIG-Ⅰ(retinoic acid inducible gene-Ⅰ),has recently been identified for recognition of the viral RNA.

在真核生物体内，除了定位于内吞体膜上的TOLL样受体能够识别入侵机体的病毒RNA，启动机体抗病毒的固有免疫反应外，近年来发现了另一种能够识别病毒RNA的细胞质内受体——RIG-Ⅰ。

Methods To use Ce3+ or Pb2+ as capture agents to detect carbonic anhydrase, Na+-K+-ATPase, Mg2+-ATPase, 5' –nucleotidase and NADPH oxidase activities on endosome membrane in epithelial cells of renal proximal tubules、hepatic cell of rat and human leukocytes. with cytochemical method.

用细胞化学方法，以Ce3+或Pb2+作捕捉剂，分别检测碳酸酐酶，Mg2+-ATP酶，Na+- K+-ATP酶，5'-核等酸酶，NADPH oxidase在大鼠肾近曲小管上皮细胞、肝细胞以及人体嗜中性白细胞内吞体膜上的酶活性。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。