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For although many modern commentators incline either to Italy (on account of xiii, 24), or to Alexandria (on account of the reference to a letter of Paul to the Alexandrians in the Muratorian Canon and for other reasons), or leave the question undecided, yet the entire letter is best suited to the members of the Jewish Christian Church of Jerusalem.
因为尽管许多现代评论家倾斜要么意大利(到十三, 24岁),或以亚历山大(上到交信保的Alexandrians在穆拉多利佳能和其他原因),或假的问题作出决定,但整个信是最适合的成员犹太基督教会在耶路撒冷。
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Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.
绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。
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The primary function of either type is to strip the workpiece from a cutting or noncutting punch or die.
主要功能或类型将脱衣来自一个切断或非锐利的打洞器或一钢模的细工品。
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The earlier phase of a diffuse goiter leading up to this point may have resulted from either "endemic" goiter (seen in parts of the world where dietary deficiency of iodine may occur) or the uncommon "nonendemic" or sporadic goiter (young adult women are most often affected).
弥漫性甲状腺肿早期就是这种病理变化,可能的病因如下,地方性甲状腺肿(在一些饮食缺碘地区可能发生)或少见的&非地方性&或散发性甲状腺肿。
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The earlier phase of a diffuse goiter leading up to this point may have resulted from either "endemic" goiter (seen in parts of the world where dietary deficiency of iodine may occur) or the uncommon " nonendemic " or sporadic goiter (young adult women are most often affected).
弥漫性甲状腺肿的早期可能是由于地方性甲状腺肿或非地方性甲状腺肿。
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If the function takes a nonreference type, then const is ignored on either the parameter type or the argument. That is, the same instantiation will be used whether we pass a const or non const object to a function defined to take a nonreference type.
如果函数接受非引用类型,形参类型实参都忽略 const,即,无论传递 const 或非 const 对象给接受非引用类型的函数,都使用相同的实例化。
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If utilitarianism is wron9, a proponent of economic analysis has a choice : He or she can either abandon the normative use of the Pareto criteria in favor of a nonutility — based efficiency criterion or try to construct nonuti1itarian normative arguments for the Pareto criteria ...
如果功利主义是错误的,那么经济学分析的支持者就有了一个选择:即或是为了非效用基础效率标准,他或她可以抛弃帕累托标准的规范用途,或是为了帕累托规范构建非功利主义规范的观点。
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About 48%(90/194) were below 29 years of age. Ninety-nine of 194 cases had either radiotherapy alone or supplementary treatment with radiotherapy following surgery. We analyzed multiple prognostic factors. The factors of importance included postoperative radiotherapy; female in glioblastoma multiforme; the primary tumor dose above 5000 rads and/or whole brain irradiation in malignant astrocytoma and glioblastoma multiforme; the primary tumor dose above 4500 rads in ependymoma, medulloblastoma and oligodendroglioma; and spinal axis irradiation above 2000 rads in ependymoma and medulloblastoma that produced a better prognosis than in other groups.
男与女之比例为2.7比1,年龄分布自1至81岁,平均年龄33.3±19.3岁,中值年龄为34岁,29岁以下占48%(90/194),其中99例单独或手术后辅以放射腺治疗,分析同种脑瘤的预后因素,其中多形神经胶母细胞瘤有手术后放射线治疗或女性,多形神经胶母细胞瘤合并星细胞瘤原发肿瘤剂量5000雷得以上或曾全颅腔照射,神经管胚细胞瘤,间胶质母细胞瘤,及室管膜瘤原发肿瘤剂量4500雷得以上,室管膜瘤及神经管胚细胞瘤有脊轴照射2000雷得以上预后均佳,且统计上有显著的差异。
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Osmotically produced "root" pressures, which may reach several hundred kPa, either force emboli into solution or push the air out of hydathodes or open vessel ends Sperry et al. 1987, Fisher et al.
渗透地生产了&根&压力,可能到达一些百 kPa,或力量 emboli 进入解决之内或者由于 hydathodes 或公开船结束(Sperry 等人 1987,渔人等人 1997)推动空气。
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Although LEDs do experience a gradual and permanent reduction in light output during their normal operating life - caused either by a reduction in the light-generating efficiency of the LED die, or a reduction of the optical path within the LED package - the Dialight street LEDs are expected to provide about 70 per cent of their original light output after 50,000 hours or 10 years, provided that they are not overdriven.
在正常操作下,LED必需要经历光输出逐渐减少的过程,而这个过程是会一直持续着的。导致光输出减少的原因可能是由于LED产生光的效率在降低,或者是由于LED压缩包内的光径在减少。不过,只要没有超负荷使用,Dialigh的LED路灯在工作50,000小时或10年后,还可以达到70%原始光输出的能力。
- 相关中文对照歌词
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- 推荐网络例句
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I didn't watch TV last night, because it .
昨晚我没有看电视,因为电视机坏了。
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Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.
今年以来,在北京的很多小区里,电梯液晶电视被撤了下来。
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I'm running my simile to an extreme.
我比喻得过头了。