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Topiramate induced hypohidrosis is reversible, but can be clinically significant during heat stress and exercise challenge. This side effect challenges patients'confidence of long term drug therapy. On the other hand, although hypohidrosis is an adverse effect of topiramate when used for other indications, its anti-sweat producing effects may be beneficial in conditions of hyperhidrosis. How topiramate induces its antiperspirant effects is unclear.

托吡酯减少汗液分泌的确切机制尚不明确，对这一问题的探讨可为有效地预防、对抗此种副作用的发生提供依据，从而提高癫癎患者药物治疗的依从性和治疗效果；另一方面，多汗症的治疗手段较少，效果亦欠佳，对托吡酯引起泌汗障碍的机制进行研究可以化害为利，为托吡酯治疗多汗症提供实验证据。

MethodsThe effects of different parts of Hyssopus officinalis on bacteria were measured by MIC and filter paper diffusion, while the effects of relaxing the contraction of tracheal smooth muscle induced by carbachol and histamine were evaluated respectively.

方法分别以最低抑菌浓度法和滤纸片扩散法比较评价神香草精油和水提物抗菌作用，以卡巴胆碱（carbachol，CCh）和组胺（histamine， His）致气管平滑肌收缩，观察神香草精油的解痉作用。

This suggests that the effects of temperature on growth of the two coral species were different. Growth rates of S. hystrix at 25℃ were stable and higher than those of S. pistillata. However, the effects of temperature on growth rate of S. hystrix may be modified by other factors (e.g., mesocosm effect) in higher or lower temperatures. The mortality of S. pistillata in three temperature treatments was very low, while the partial mortality of S.

这些结果显示，两种珊瑚在不同温度下的生长反应有所差异，在适温环境下，尖枝列孔珊瑚的生长稳定且高於萼柱珊瑚，但萼柱珊瑚却会受到其他因素影响；在较高和较低温时，萼柱珊瑚生长没有受到生态箱效应影响，而温度对於尖枝列孔珊瑚生长率的影响可能受到生态箱效应而改变。

Pupation rate, immatured worm, dead cocoon rate, cocoon shell weight, cocoon weight, percentage of cocoon shell weight, cocoon crop from 10000worms and cocoon shell weight from 10000 worms were controlled by genes with additive and dominant effects, but no epistatic effects in these traits.

结果表明，家蚕的虫蛹率、幼虫生命率、死笼率、全茧量、茧层量、茧层率、万蚕收茧量、万蚕茧层量8个性状同时受基因的加性效应和显性效应控制，不存在上位作用，茧层量、茧层率、万蚕收茧量呈现部分显性，虫蛹率、幼虫生命率、死笼率、全茧量、万蚕茧层量5个性状则呈现超显性。

The aim of this work is to consider some general regularities observed in the interferent effects occurring in two-component systems composed of an analyte and one interferent, and to describe these effects by a general equation.

本文旨在研究包括待测元素和干扰元素的两元体系中干扰效应的一些规律，筛选出表达其相互关系的数学模型。

We introduced improved primary mixed glial culture and different-attachment method to isolate and purify the OPCs, the cells were proliferated in serum-free medium, flow cytometry and immunohischemistry methods were employed to estimate the purity of cultured OPCs. Their abilities of differentiation and expression of trophic factors were identified by RT-PCR and immunostaining. Several methods including TUNEL and MTT were adopted to estimate the protective effects of conditioned culture medium from oligodendrocyte lineage cells on the primary cultured cerebellar granule neurons. Intravitreal transplant of OPCs, combined with retrograde fluorescent labeling the superior colliculus and intraorbital optic nerve transection, were used to investigate the protective effects of OPCs on the axotomized RGCs in vivo. Intravitreal transplantof OPCs or NSCs on the newborn rats, and retinal transplant of OPCs on the young rats were performed, to observe the myelin formation in the retina at different stages after cellular transplantation. Optic nerve transection was carried out on some rats with myelinated retinae, to study the influence of myelination on the injuried RGCs.

为此，本研究采用改良的胶质细胞混合培养与差速贴壁方法获得大鼠OPCs，使用无血清培养基进行扩增、培养，用免疫组织化学和流式细胞技术对培养细胞的纯度进行鉴定，对少突胶质系细胞表达部分营养因子的情况进行检测；采用TUNEL、MTT等方法对少突胶质系细胞条件培养基对原代培养小脑颗粒神经元的保护作用进行检测；将OPCs移植入成年SD大鼠玻璃体内，利用上丘逆行荧光标记技术，观察眼内移植的OPCs对眶内视神经切断时的视网膜神经节细胞的保护作用及其持续时间；将OPCs或NSCs移植入新生和幼年SD大鼠玻璃体或视网膜内，观察不同时期视网膜内髓鞘形成与分布特点，分析髓鞘的超微结构，并观察眼内髓鞘形成对损伤神经节细胞的保护作用。

Involucrate seedlings. The results showed that all test reagents had positive effects, and synergistic effect existed among them. CaCl2 and SA improved the water utilization efficiency of D. involucrate at the initial stage of water stress, while water-retention agent maintained higher soil moisture content when the drought stress developed so as to improve the drought resistance of D. involucrate and alleviate the effects of water stress.

结果表明：CaCl2、SA和保水剂对珙桐幼苗抗旱性的影响均呈正向作用，且它们之间具有协同效应；CaCl2和SA提高了珙桐幼苗在水分胁迫前期对土壤水分的利用，使幼苗维持了较高的抗旱性；随着土壤干旱的持续，保水剂对水分胁迫有缓效作用，使土壤维持了较高的水分含量，有利于保持幼苗的抗旱性，减小水分胁迫的危害。

The results from the experiments indicated the effects of He-Ne laser were very similar to microwave's effects on Isatis Indogotica. These results suggested that He-Ne laser and microwave have similar biology efeect.

比较研究了激光和微波处理菘蓝种子萌发过程的热力学参数以及萌发后子叶5种酶活性，发现激光和微波具有相似的效果，从而说明激光对生物的作用效应必然是电磁效应和热效应。

In order to enhance the compatibility of ABS/PP/CaCO3 composites, the effects of reactive blends of the composites were studied by using Haake rheometer. The effects of various assistant cross-linkingers, such as castor oil, triallyl isocyanurate, turpentine (JS-1) and glycol dimethacrylate, and the used amount of cross-linkinger-dicumyl peroxide on the torques of the melting composites were investigated.

为提高ABS/PP/CaCO3复合材料相容性，采用转矩流变仪观察了ABS/PP/CaCO3三元复合物反应性共混后的扭矩，考察了不同的助交联剂蓖麻油、异氰脲酸三烯丙酯、松香酯(JS-1)、二甲基丙烯酸乙二醇酯以及交联剂过氧化二异丙苯的用量对共混物的影响。

Results showed that DCF with different dosages could increase the frequency of micronucleated erythrocytes markedly,except the first injection of the dosage with 5 and 10 mg/kg,every group caused an increase in the frequency of nuclear abnormality erythrocytes,the effects in cell membrane and cytoplasm were less than the effects in karyon by DCF,and the most toxicity was exhibited after the second injection.

结果表明，注射DCF后所有剂量组均能引起中华蟾蜍红细胞微核细胞率显著升高；除5，10mg／kg剂量组在第1次注射后较对照组低外，其他注射剂量和次数均引起核异常细胞率升高，DCF对细胞膜与细胞质的影响小于其对细胞核的影响，在4次注射中以第2次注射后对红细胞的毒性效应最大。

The production moved off-Broadway to New York City, where she won the Joseph E. Calloway award for her performance, and was profiled in American Theater Magazine as one of ten young theater artists to watch.

生产提出过百老汇的新的纽约市，在那里她赢得了约瑟夫calloway奖，她的表现，并于异型在美国的战区杂志之一， 10战区的青年艺术家观赏。

It's a risk tradeoff, and I believe that adding test support code usually wins.

这是一个风险的权衡，我相信添加测试代码通常会占上风。