查询词典 effects

AIM: To isolate bioactive secondary metabolites from the fruits of Schisandra rebriflora Rehd. et. Wils and study their effects on HIV-1 infectivity. METHODS: Inhibition of syncytia formation, HIV-1 reverse transcriptase and protease, protection of HIV-1 infected cells, level of HIV-1 p24 antigen,blockage of fusion were detected. RESULTS: A lignan compound, named rubrifloralignan A, was first isolated as a natural product with modest inhibition effects on syncytium formation and HIV- 1 replication and could protect HIV-1 infected cells with weak inhibition effects on fusion and RT, but it showed no effects on the replication of HIV-1 chronic H9 and PR. CONCLUSION: Rubrifloralignan A is an efficient anti-HIV-1 product with effect on early stage of HIV-1 replication.

目的：从红花五味子果实中寻找活性代谢产物，研究其抗HIV—1活性和作用机制方法：通过合胞体抑制、HIV-1感染细胞保护、HIV—1p24抗原测定、融合阻断、逆转录酶和蛋白酶活性分析等实验，检测分离化合物的抗HIV—1活性并探讨其作用机制一结果：红花五味子甲素能够抑制病毒诱导的合胞体形成，保护病毒感染细胞，抑制病毒在细胞内的复制对HIV-1感染细胞与正常CD4^＋细胞间的融合，逆转录酶活性有一定的抑制作用但是红花五味子甲素不抑制病毒在慢性感染细胞中的复制，也不抑制蛋白酶的活性、结论：首次从天然产物中分离得到红花五味子甲素，它对HIV—1病毒复制早期具有抑制作用

Based on these previous work, in this research, in order to explore the the molecular mechanism of enhanced tumor cell immunogenicity treated by elemene and mytomycin C compositely, we used murine Hca-F ascitic hepatic carcinoma ( high lymphatic metastasis substrain of H22) as an experimental model to compare the immunoprotective effects on Hca-F cells as well as the mechanism of the effects caused by HSP70-peptide complex purified from untreated tumor cells, EC-TCV and BCG; We studied the mechanism of increased tumor cell membrane HSP expression treated with elemene by the techniques of RT-PCR and immunoelectron microscopy; In order to deeply elucidate the antitumor effects and the molecular mechanism of elemene in increasing tumor cell immunogenicity we analyzed and compared the effects of elemene and heat shock on the gene expressions of tumor cell using gene expression profile chip.

本论文在上述研究成果的基础上，选择小鼠肝癌H22的高淋巴道转移亚系Hca-F为模型，进一步比较了未处理肿瘤细胞来源、榄香烯复合瘤苗来源的和卡介苗来源的HSP70-肽复合物对Hca-F的免疫保护效应、效应机制，探讨榄香烯-丝裂霉素复合处理增强肿瘤细胞免疫原性的分子机制；以Hca-F和人肝癌细胞株HepG〓等为模型研究了榄香烯处理增强肿瘤细胞膜热休克蛋白表达的机制；以HepG〓为模型用表达谱基因芯片研究比较了榄香烯与热休克处理对肿瘤细胞基因表达的影响，从而进一步阐明榄香烯抗肿瘤作用及增强肿瘤细胞免疫原性的分子机制。

The methods proposed by Wang et al (1999) could analyze additive effects, additive by additive epistatic effects and their interaction with environments, but could not estimate dominance effects and epistatic effects related to dominance.

Wang等(1999)的方法能够分析加性效应、加加上位性效应及其与环境的互作效应，但无法估计显性以及与显性有关的上位性效应。

The electric conductivity of solid polyiodides increases largely as the aggrandizement of polyiodide anions"polymerization degree. The solid polyiodides have excellent sterilizing effects and the effect of tetra-n-butyl ammonium undecaiodide is the best of them, and the sterilizing effects increase as the aggrandizement of polyiodide anions" polymerization degree. The sterilizing effects of resinic polyiodides increase as the aggrandizement of polyiodide anions polymerization degree, the heptaiodide resinic polyiodide has better sterilizing effects than the triiodide and pentaiodide.

固体高聚碘系列化合物的电导率随着高聚碘阴离子聚合度的增加而增加，并且增幅较大；固体高聚碘对常见细菌均具有很好的杀灭作用，并且随着高聚碘阴离子聚合度的增加，杀菌能力也随着增强，其中正四丁基十一碘化铵杀菌剂的效果最佳；树脂高聚碘随着高聚碘阴离子聚合度的增加，杀菌能力增强，碘七树脂高聚碘的杀菌效果要明显好于碘三树脂和碘五树脂高聚碘。

Monte Carlo simulations were conducted to study the new approaches of QTL mapping, the results indicated that general least squares method, which was widely applied in mixed linear model, could unbiasedly estimate all genetic main effects, including additive effects, dominance effects and epistatic effects of additive by additive, additive by dominance, dominance by additive, dominance by dominance.

对新提出的QTL分析力法进行了Monte Carlo模拟研究，结果表明，广泛应用于混合线性模型的广义最小二乘法能够无偏估计加性效应，显性效应以及加加、加显、显加、显显上位性效应等各项遗传主效应；运用线性无偏预测法能够无偏预测上述各项遗传主效应与环境的互作效应；基于QTL效应的杂种优势预测也是无偏的。

There were no significant facilitating effects to the retention of signaled information in the overuse of text signals condition, but there were in the selective use of text signals condition. Experiment 3, in which 2 small experiments contained, studied the effects of reader-based factors. Experiment 3a examined the effects of the familarity to the text topics and the readers' reading levels. Experiment 3b explored the effects of cognitive style and the intention to use the text signals. The results were as the follows: There were no significant difference between the signaled and unsignaled conditions in the circumstance of high familarity to the text topics, but there were significant differences between them in the circumstances of lower familarity to the text topics. There were no significant differences between the signaled and unsignaled conditions for the field-independent participants, but there were for the field-dependent participants. All the participants with different reading levels were helped by the text signals.

实验3 对不同主体因素条件下文章标记效应进行了研究，分2个分实验，实验3a以高中二年级学生为被试，研究了文章主题熟悉程度与阅读水平对文章标记效应的影响，实验3b以初中二年级学生为被试，探索了读者不同的认知方式与标记利用的意向对文章标记效应的影响，实验3结果发现，读者的阅读水平、对文章主题的熟悉程度、认知方式和利用标记意向等因素影响着文章标记效应，在文章主题熟悉的条件下，有无文章标记无显著差异，但在主题不熟悉条件下，有文章标记的效果显著优于无标记的效果；对场独立被试而言，有无标记无显著差异，但对场依存被试来说，有标记条件显著优于无标记条件；文章标记对不同阅读水平被试都有显著促进效应；文章标记利用意向对场独立与场依存被试都有显著促进效应。

This may be explained by follows: First, Decoction Shenkangling can regulate the homeostasis of NEI network and reduce the increased activity of NF-κB to restrain the action of inflammatory-sclerotic media; Second, it can redress the disequilibrium of the ratio of TXA2/PGI2 to reform the hypercoagulable state; Third, it can enhance albumin and reduce cholesterol and triglyceride; Fourth, it can amend the renal damage and protect the function of renal tubule and stroma to prevent the transformation from MCD to FSGS; Last, it can lessen urine protein in AN rats markedly and relieve the side effects of prednisone.4. NF-κB, TXA2 and PGI2, along with the renal pathomorphology and so on can all be the indexes of the diagnosis of Symptom of "Kidney Deficiency and Blood Stasis" and the application of Methods of "Benefiting the kidney and Promoting blood circulation" in TCM.5. The curative effects on AN rats by treatment of integrating Traditional Chinese Medicine with prednisone are much better than using prednisone only. And the curative effects on AN rats by treatment of matching Decoction Shenkangling, having the function of "Benefiting the kidney and Promoting blood circulation", with Prednisone are much better than using Prednisone only.6. When it referred to decreasing urine protein, cholesterol and triglyceride and increasing albumin, Decoction Zhibodihuang excesses Decoction Taohongsiwu. However, when it referred to regulating the disequilibrium of TXA2/PGI2 and meliorating renal lesion, Decoction Taohongsiwu exceeds Decoction Zhibodihuang.7. The curative effects on AN rats by treatment of matching Methods of "Benefiting the kidney and Promoting blood circulation" with Prednisone overmatches using Prednisone matching Method of "Benefiting the kidney" or Method of " Promoting blood circulation" only.

益肾活血中药肾康灵能显著改善AN鼠的肾虚血瘀证的临床表现和实验指标，这可能与中药肾康灵能调理AN鼠机体的NEI网络功能稳态，降低异常升高的NF-κB活性，抑制免疫炎症/硬化介质环节，纠正失衡的TXA2/PGI2，改善AN鼠血液高凝状态，提高AN鼠的血清Alb，降低Ch和TG，减轻AN鼠的肾脏组织病理学变化，保护肾小管－间质功能，阻止MCD向FSGS转化；显著减轻AN鼠的尿蛋白水平以及减轻激素副作用有关。4、NF-κB、 TXB2和6-keto-PGF1α以及肾脏病理形态学改变等，都可作为中医肾虚血瘀证诊断和益肾活血法应用的客观指标。5、中西医结合干预AN鼠疗效优于单纯激素治疗；强的松配合益肾活血中药肾康灵组的综合疗效显著优于单纯强的松组。6、知柏地黄汤组在降低尿蛋白、提高血清Alb、降低Ch和TG疗效上优于桃红四物汤组；桃红四物汤组在纠正失衡的TXA2/PGI2和减轻肾脏病理损害方面优于知柏地黄汤组。7、激素配合益肾活血法干预AN鼠在一定程度上优于激素配合益肾法或活血法。

And it was found that: certain good effects could be obtained in wood color improving treatment by single bleaching; the effects were not obvious using the prescriptions of sulfides; but the effects were obvious using the prescriptions of hydrogen peroxide or Javel water, and good bleaching effects could be gained.

结果发现：单纯漂白可获得一定的材色改良效果；硫化物类药剂配方，效果不明显；双氧水类、次氯酸钠类药剂配方，效果明显，可得到很好的漂白效果。

First, the effects of magnetic RAM relaxation time and the rise-time of incident pulse signal on reflection signal are discussed, the relationship between the rise-time of incident pulse and relaxation time based on the energy of reflection signal is revealed. Then, the effects of magnetic hysteric, susceptibilities and saturation upon reflection signal are analyzed, the results reveal the reflection of RAM target and UWB signal design. In the meantime, dielectric relaxation time effect about dielectric RAM target is analyzed simply, and the effects of relaxation time and the width of incident pulse upon reflection signal are probed. Finally, a few RAM targets are measured in the chamber using the impulse radar experiment system which is developed by the team of anti-stealth impulse radar on Department of Electrical Engineering, National University of Defense Technology. The experimental results show the similarity of the rule of echos with the theory. From the compared results of different tagets, we concluded, compared with 15% wideband sinusoidal signal, the impulse signal has increased 10～12dB energy from the same loaded RAM target; this, in turn, shows the nonlinear effects of RAM to the echoes, and the potentiality of the impulse signal to RAM targets.

首先分析了磁性RAM的弛豫时间及入射脉冲信号的上升时间对反射信号的影响，从反射信号能量角度出发，给出了入射脉冲上升时间与弛豫时间的关系；接着分析了磁性RAM的磁滞特性、磁化率及磁化强度对反射信号的影响，给出了RAM目标辐射和有关UWB信号设计的一般性结论；其次，对介电RAM的弛豫时间效应作了简单的分析，探讨了介电弛豫时间及入射脉冲宽度对反射信号的影响；最后利用国防科技大学电子技术系&反隐身冲激雷达技术研究组&研制的冲激雷达实验系统，在微波暗室中对几种不同的RAM目标进行了测量，结果表明：其反射波形的基本规律与上述理论分析相一致；从各种不同目标回波的能量对比结果得出，涂覆RAM目标对冲激信号的吸收比15％带宽的正弦信号要小10～12dB，证实了RAM的非线性效应对回波的影响，也证实了冲激信号反隐身的潜力。

Throughout comparing the above estimating methods, we have the following results: the estimators of the moments of the errors does not depend on the random effects, and that of the random effects does not depend on the errors, and then the corresponding asymptotic variances are very simple and optimal; when the random effects are multivariate, we can not construct different estimating equations for the random effects and errors respectively, which results that the asymptotic covariances of estimation are very complex and then the estimating efficiency is bad.

比较上述两种估计法，我们发现：当随机效应是一维的时侯，误差的各阶矩的估计不依赖不可观测的随机效应，随机效应的估计也不依赖误差，因此，估计的渐近方差结构特别简单也是最优的；而当随机效应是多维的，因为随机效应的协变量的影响，我们没有办法针对随机效应和误差的各阶矩分别建立估计方程，这导致所得的估计的渐近方差或者协方差矩阵特别复杂，从而估计的效果不是很好。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。