查询词典 ectatic

Genetic factors,obesity, high salt consumption, and alcohol may be involved in the pathogenesis of essential hypertension. Jannetta et al. suggested that essential hypertension might be associated with vascular compression of the left rostral ventrolateral medulla and the root entry zone of cranial nerves Ⅸ and Ⅹ by ectatic loops of posterior fossa arteries,described as neurogenic hypertension.

原发性高血压的发生可能与遗传、肥胖、高盐饮食、饮酒等综合因素有关。1979年Jannetta等提出由于后颅窝异常血管袢压迫延髓左侧腹外侧、舌咽神经与迷走神经根入脑干区(Root entry zone， REZ)而引起高血压即神经源性高血压的假说以来，不少学者从临床及实验研究证实了Jannetta的假说。

Essential hypertension caused by neurovascular compression of the left ventrolateral medulla was associated with malbalance of vasomotor center in the dorsal medulla. The possible pathogenesis was the following:① An irritation of the left RVLM by pulsatile compression of an ectatic vessel would increase activity of central sympathetic neuron.② Neurovascular compression at the REZ of the cranial nerves Ⅸ and Ⅹ decreased excitation of parasympathetic nerve.③ Decreased sensitivity of afferent inputs to neuron of nucleus tractus solitarii in the sensory area lead to hyperactivity of central sympathetic nervous system due to pulsatile compression of the left RVLM.④ Neurocompression of the left RVLM and REZ in the left cranial nerves Ⅸ and Ⅹ lead to an overactivity of central renin angiotensin system.

3，结论：左侧延髓腹外侧Ⅸ、Ⅹ颅神经REZ动脉血管压迫所导致的高血压的发生与左侧延髓血管运动中枢对血压的调节失衡有关，其可能机制是：①左侧RVLM在搏动性血管压迫刺激下，中枢交感神经元活性增高；②左侧Ⅸ、Ⅹ颅神经REZ受压导致副交感神经兴奋性降低；③感受区孤束核神经元接受迷走神经传入冲动的敏感性减低，导致中枢交感神经活性增高；④左侧RVLM及Ⅸ、Ⅹ颅神经REZ受压引起中枢RAS活性增加。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。