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So people attach great importance to the damage by its toxicity. The main target organ of manganese is nervous system. At the early stage, its major symptoms are neurasthenic syndrome and autonomic nerve functional disorder, and then the apparent damage to extracorticospinal tract nerves, similar to that of a Parkinson's disease.

锰的主要毒作用器官是神经系统,早期以神经衰弱综合征和植物神经功能紊乱为主,继而可出现明显的锥体外系神经受损症状,与帕金森病(Parkinson's disease,PD)症状类似,流行病学研究认为锰是PD发病的环境危险因素之一。

The decisive processes lied on neurectomy. Though the selective posterior rhizotomy and selective peripheral neurectomy reduced muscular strength partially in the early stage, the muscular tension was also reduced, therefore the range of motion of joints was enlarged and the functions of extremities were strengthened.

能降低肌张力的决定性手术是在神经部位手术,选择性脊神经后根切断术和选择性周围神经切断术早期有部分的肌张力下降,由于降低了肌张力,使关节活动度和肢体控制能力增强,功能明显好转。

The results indicated that EMP can promote necrosis and apoptosis of hippocampal neurons,induce morphological changes in blood vessels, neuroglia cells and neurons at early stage, which may be the possible injury mechanism in rat brain induced by EMP.

表明大鼠大脑受电磁脉冲辐照后早期海马区可发生神经细胞坏死和凋亡,以及各组织成分的病理形态学改变,上述变化可能与电磁脉冲致细胞DNA损伤有关。

Relationship between differentially expressed genes and epigenetic modification during the early stage of esophageal carcinoma induced by nitrosamine.

亚硝胺诱导食管癌变早期基因差异表达与表观遗传修饰的关系。

2Its one of cytology mechanisms of Qiang-gu-bao decoction on preventing and curing diabetes osteoporosis were related with promoting for osteoblastic cell proliferation 、 differentition and mineralization of formation,moreover inhibiting nonenzymic glycation reaction and reducing the formation of AGEs on the early stage, inhibiting the secretion of osseous absorptive cytokine, Consequently, Qiang-gu-bao decoction could inhibited bone resorption and promote for bone formation as well as regulated the bone metabolization.

2强骨宝方直接提取液及糖尿病模型大鼠载药血清均能促进 OB 增殖、分化及矿化成骨作用,并抑制早期糖基化反应,减少 AGEs 的形成,抑制 OB 分泌骨吸收因子,从而达到抑制骨吸收、促进骨形成、调节骨代谢,这可能是强骨宝方防治糖尿病性骨质疏松的细胞学机制之一。

Owing to its more intensive nonhomogeneity, the limitation by recognition and information during the early stage of gas pool development, the west Sichuan dense clastic rock gas pool is hard to be accurately judged and predicted for its beneficial reservoir ing blocks by geological and geophysical exploration.

川西致密碎屑岩气藏由于其较强的非均质性,在气藏勘探开发早期,由于认识和资料的限制,地质、物探对储层有利储集区块难以进行准确的判断和预测。

Methods Tissue culture was used to study the cataractous lenses of rats induced by sodium selenite or galactose. At the early stage, the content of nonprotein sulfhydryl, protein sulfhydryl, non-soluble disulfide bond, malonaldehyde and the activities of glutathione peroxidase, glutathione reductase and glutathione-S-transferase were measured in the cataractous lenses, and they were compared with that of the normal lenses. Results The two kinds of material could all induce cataract in rats, sodium selenite being more potent.

采用器官培养方法,以不同浓度亚硒酸钠及半乳糖作用于晶状体,诱发大鼠晶状体形成白内障,在培养初期测定晶状体内非蛋白质巯基(nonprotein sulfhydryl, NP-SH、蛋白质巯基(protein sulfhydryl ,P-SH)和不溶性蛋白质二硫键的含量,脂类过氧化水平,以及与谷胱甘肽代谢有关的谷胱甘肽过氧化物酶(GSH peroxidase, GSH-PX)、谷胱甘肽还原酶(GSH reductase, GSSG-R)及谷胱甘肽硫转移酶(GSH S transferase, GSH-S)的活性。

In the early stage of NPR, the algorithms are implemented using software and executed in CPU.

早期的NPR技术停留在软件层面上,所实现的算法往往主要依靠CPU来运算。

And it is found that oogenesis in Drosophila and ant is similar to theoocyte apoptosis. Yolk mainly occurred in the early stage of apoptosis, which may bedue to environmental factors such and is the adaptability of the adverse environmentalmeasures.

并发现,拟黑多刺蚁与果蝇卵子发生有相似的卵母细胞凋亡现象,主要发生在卵黄形成前期,这种凋亡可能是由于环境因素的影响,对不良环境的适应性对策。

Therefore, CRP could mediate E-LDL participating in the early stage of atherogenesis. CRP is an ancient conserved protein whose initial role as a pattern recognition molecule may have been to defend against bacterial infections, but whose present biological role appears quite complex. CRP is protective against a variety of bacterial infections and inflammatory stimuli as an opsonin. It is likely that the activity of CRP in humans is either pro- or anti-inflammatory is dependent on the context in which it is acting.

由于CRP的识别相可以结合被暴露出磷酸胆碱结构的E-LDL,形成E-LDL/CRP复合体,而内皮细胞表面能以高亲和力识别CRP的配体相,从而CRP-相性结构具有结合E-LDL,被内皮细胞捕获,引起脂质沉积和激活补体、触发炎症反应的可能性,这样可以解释早期动脉粥样硬化为何同时存在E-LDL、CRP、补体,而这三种物质在同时、同地出现绝非一个巧合。

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