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Therefore, CRP could mediate E-LDL participating in the early stage of atherogenesis. CRP is an ancient conserved protein whose initial role as a pattern recognition molecule may have been to defend against bacterial infections, but whose present biological role appears quite complex. CRP is protective against a variety of bacterial infections and inflammatory stimuli as an opsonin. It is likely that the activity of CRP in humans is either pro- or anti-inflammatory is dependent on the context in which it is acting.

由于CRP的识别相可以结合被暴露出磷酸胆碱结构的E-LDL，形成E-LDL／CRP复合体，而内皮细胞表面能以高亲和力识别CRP的配体相，从而CRP-相性结构具有结合E-LDL，被内皮细胞捕获，引起脂质沉积和激活补体、触发炎症反应的可能性，这样可以解释早期动脉粥样硬化为何同时存在E-LDL、CRP、补体，而这三种物质在同时、同地出现绝非一个巧合。

ABSTRACT Immobilized penicillin acylase (from E.coli) was used to catalyze 7 phenylacetamido 3 E propenyl cephalosporanic acid hydrolyzation into 7 amino 3 E propenyl cephalosporanic acid. Then, trans APRA was acylated with hydroxyethyl ester of 4 hydroxy D phenylglycine to obtain trans cefprozil.

以7 苯乙酰氨基 3 E 丙烯基 3 头孢菌素 4 羧酸为原料，在青霉素酰化酶作用下，首先酶法水解得到3 E 丙烯基 3 头孢菌素 4 羧酸，过滤固相酶，滤液调pH分离得到反式APRA固体；在青霉素酰化酶作用下，反式APRA再与对羟基苯甘氨酸乙二醇酯缩合，得到反式头孢丙烯；酶法合成所得的产品与进口反式头孢丙烯对照品一致。

This article emphasis PKM in the environment of E-Learning, following: its development in China and other countries, the concept and skill, PKM's actualization and give an example then design a main framework for a characteristic search engine, its dynamic concept in the environment of E-Learning, Finally prefigure its trend about PKM's development in future and face challenge.

本文就是在E—Learning与个人知识管理整合发展的前提下，重点研究了E—Learning 环境下的个人知识管理，包括其国内外发展情况对比，概念，技能，以及E—Learning 环境下PKM 的具体实施过程及实施案例，并以此为基础设计了一个个性化搜索引擎的主要流程图来支持PKM，最后预见了PKM 的未来发展趋势及其所面临的挑战。

e-PTFE was implanted into the pitting area after subcuntaneous disjunction. Results: 15 cases were followed for about 3 and 6 momths after implant of e-PTFE, including cases with saddle nose, pitting deformity of orbit, congenital lip cleft with depressed soft tissue around pyriform opening, parbial defect of helix. In these cases, satisfaction rate is evaluated as high as 97.9%, unexpected tissue response was not shown in this clinical trail.Conclusion: Depended on this clinical trail, we believe local e-PTFE manufactured by Shanghai Suo-kang Medical Implants Co., Ltd.

由于e-PTFE的组织相容性好，在80年代初期一些发达国家已经应用于整形美容外科[1]，尤其应用于隆鼻术、面部凹陷畸形的整复、唇线增高、唇加厚、鼻唇沟过深的整形美容术、耳廓缺损等手术中，学者们认为e-PTFE排斥反应的发生率低，弹性和硬度与软组织相似，周围组织细胞能够长期进入移植物内，不形成纤维囊，在整形美容外科领域有重要的应用价值。

For vortex-liquid phase,the E-J relation could be described according to the Kim-Anderson model:U=U0(1-J/JC).While for vortex-glass phase,the electric field decays verydramatically with decreasing current density,so it is difficult to be observed with theinstrument has limited precision.In the intermediate current region,the E-Jrelations of the both phases could be fitted in terms of a phenomenological model:U=(U0/μ)[μ-1],it was concluded that the sign of μ-value changes fromnegative to positive when the temperature decreases lower than the glass-transitiontemperature Tg,meanwhile,the activation energy U enhances dramatically.Whilein the large current region,Zeldov's logarithmic model was suitable for fitthing theE-J curves of the both phase.Moreover,there was no abrupt change of U or thecharacteristic current density IC.However,the effective radius of vortex line variesremarkably around Tg.

对于涡旋液体相，小电流区的E-J关系可以用计及反跳的Kim-Anderson模型U＝U0(1-J/JC)来描述，而对于涡旋玻璃相，小电流区的电场随电流密度减小而迅速衰减，以致很快脱离了实验测量精度的范围；在中等电流区，两相的E-J关系可以用共同的唯象过渡模型U＝(U0/μ)[μ-1]来拟合，得到在玻璃转变温度Tg两侧μ值由正到负的变化，同时激活能U在Tg以下迅速升高；在较高电流区，两相的E-J关系可以很好的用Zeldov对数模型来描述，拟合结果表明U在Tg两侧的趋势没有明显变化，但是涡旋线的有效半径发生了显著变化。

METHODS: Benzhydroxamic acid derivative E was artificially synthesized. The gastric cancer line 7901 was selected to serve as the target cell. The effect of medicine E on tumor cell activity was examined by cell culture technology in vitro. The change of morphology and the ultrastructure after treatment with medicine E was observed with the optic microscope and the electron microscope.

以胃癌细胞株7901为靶细胞，采用体外细胞培养技术评价苯异羟肟酸衍生物E对肿瘤细胞活性的影响，通过光学和电子显微镜对E药物作用后细胞形态学进行观察，用免疫组化和RT PCR方法检测细胞凋亡。

Kinds of Schiff base derivatives of 2-N-benzylidene Furanmethanamine have been designed. The Net Charges of main atoms, bond lengths, bond angles, dihedral angles, IR have been calculated by means of HyperChem6. 0 program. 36 kinds of Schiff base derivatives of benzylidene adenine have been designed. Also the net charges of main atoms, bond lengths, bond angles, dihedral angles, IR, the energy gap △E between HOMO and LUMO and the nonlinear second-order polarizability β have been calculated by means of HyperChem6. 0 program. The calculated results indicated that the nonlinear second-order polarizability β were up in accordance with the △E down.

设计了腺嘌呤缩苯甲醛36种衍生物，计算了这些分子的气相几何，腺嘌呤缩苯甲醛中各原子的电荷分布，最高占有轨道HOMO和最低未占有轨道LUMO的能量以及它们之间的能量差△E，同时还计算了这些分子的二阶非线性极化率β，我们发现腺嘌呤缩苯甲醛的二阶非线性光学系数与△E有近似一致的变化关系，随着△E的减小，二阶非线性光学系数有增大的趋势。

Type-E dualism holds that phenomenal properties are ontologically distinct from physical properties, and that the phenomenal has no effect on the physical.28 This is the view usually known as epiphenomenalism (hence type-E): physical states cause phenomenal states, but not vice versa.

E类二元论认为现象属性在存有上区别于物理属性，现象对物理没有因果作用。[28]这个观点常常被称为副现象论（所以称为E理论，副现象『epiphenomenalism』的E）：物理事态导致现象事态，但反之不可。

The intermediate which obtained from oximation of 7a-e reacted withmethyl N-(2-bromomethylphenyl)-N-methoxycarbamate to synthesize oxime ether methyl carbamate 3a-e.

以邻位卤代苯甲醛和3-丁烯-2-醇为原料通过钯催化&一锅法&反应合成了2-乙酰基茚7a-e，7a-e 肟化之后和N-(2-溴甲基苯基)-N-甲氧基氨基甲酸甲酯反应合成了肟醚类氨基甲酸甲酯3a-e，进一步胺解之后得到了肟醚类氨基甲酰甲胺3f-j。

Results On the basis of the percentage of GPI-anchored PLAP conversion,the sera GPI-PLD activities of total 172 patients,included 26 severe acute viral hepatitis as group A,29 liver cirrhosis as group B,32 chronic viral hepatitis as group C,55 mild acute viral hepatitis as group D,30 primary hepatocellular carcinoma as group E,were measured.As compared with 182 healthy presons as control group,the sera GPI-PLD activities of group A and B were significantly reduced;By contraries,the activities of group D and E were significantly raised.The sera GPI-PLD activities of group C compared with healthy control group were not significantly altered.However,when paired Q-test,the changes of serum GPI-PLD activity between all paired groups among this five groups were remarkable.

结果检测172例肝脏疾病患者(包括A组：26例急性重症病毒性肝炎；B组：29例肝硬化；C组：32例慢性病毒性肝炎；D组：55例急性非重症病毒性肝炎；E组：30例原发性肝癌)血清中GPI-PLD的活性，发现A、B两组患者的该酶活性较正常人(182名)显著性降低，而D、E两组则较正常人显著性增高，C组患者的酶活性与正常人无显著性差异，但A、B、C、D、E两组之间的酶活性水平改变却均有显著性。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失