查询词典 dystrophin

In the dystrophin gene, and in most of human genes, this genetic information is not contiguous.

在肌营养不良蛋白基因，在人类基因大多数，这种遗传信息不连续的。

DMD is caused by a mutation of the gene for dystrophin, a protein in the muscles.

DMD源于肌肉中一种称为肌营养不良蛋白的基因突变。

But when the patient is younger, It is difficult to differentiate DMD from BMD.

基因变异检测也不能区分二者，而检测肌肉中dystrophin的改变是鉴别诊断的重要方法。

In DMD, dystrophin is missing and the muscle membrane is easily damaged.

在DMD，肌营养不良蛋白丢失和肌肉膜容易损坏。

Results These two patients were confirmed to suffer from DMD. They were characterized by typical features of DMD including typical clinical manifestations, increased serum enzymes, EMG presenting myogenic impairment, HE staining presentation belonging to DMD, negative dystrophin in brother, and inconstantly positive on the sarcolemma of sister. Furthermore, no deletion or duplication was found in the 1-79 exons of dystrophin gene. The suffering brother and sister carried the same maternal X chromosome.

结果 兄妹二人符合DMD诊断，具有典型的DMD临床表现，肌酸激酶、肌酸激酶同工酶、乳酸脱氢酶、羟丁酸脱氢酶和谷草转氨酶的水平均显著高于正常值，肌电图呈肌源性损害，肌肉HE染色符合DMD，男患者的抗肌萎缩蛋白表达阴性，女患者的少量肌纤维仍可见不连续膜阳性，两患者抗肌萎缩蛋白基因的1~79号外显子未见缺失和重复突变，女患者与男患者携带相同的母源性X染色体。

Adipo R2 and Krs genes were lowest expressed in EA group. The genes of TNF-αand Utr were lowest expressed in the groups of EN and ST, respectively. This result was coincidence with that of SSH.

对脂联素受体2(Adiponectin recptor 2，AdipoR2)、赖氨酸tRNA合成酶(lysyl-tRNA synthetase，Krs)、肿瘤坏死因子α(tumor necrosis factorα，TNF-α)、Dystrophin相关蛋白(Utrophin，Utr)等4个基因进行定量PCR检测，在不同处理组小鼠肝脏中的表达情况有所不同。

In this trial, which began in March 2006, researchers injected a dystrophin gene compound called Biostrophin, which was developed with MDA support at Asklepios Biopharmaceutical in Chapel Hill, N.C., into the biceps muscles of boys with DMD.Biostrophin is a combination of miniaturized dystrophin genes and adeno-associated viral shells that home to muscle fibers.

这次试验始于2006年3月，研究人员将名为biostrophin的抗肌营养不良蛋白基因化合物（在俄亥俄州哥伦比亚儿童医院同肌肉营养失调协会的支持下，由Asklepios生物医药公司制造）注入了到DMD男孩们的二头肌中。biostrophin是由微型肌营养不良蛋白基因和来自肌纤维的腺相关病毒壳合成的。

This new research modified the introduced dystrophin gene to increase the efficiency of dystrophin protein production in the cells.

这一新的经过改造的方法，增强了抗肌萎缩蛋白在肌肉细胞内产生的有效性。

This exon is responsible for making a 34 aminoacid long fragment of the dystrophin protein.

这个外显子是负责34个氨基酸作出的dystrophin蛋白长片段。

To investigate the change of morphology and dystrophin expression in mdx mice after the bone marrow stem cells transplantation.

研究骨髓干细胞移植后mdx鼠腓肠肌组织病理变化及dystrophin的动态表达变化。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失