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Effect of drugs on invasion and migration of LS174T cells was observed in reconstructed basement membrane invading experiment.

主要观察指标:N-硝基精氨酸甲酯对LS174T细胞侵袭重建基底膜的抑制率和趋化运动抑制率。

OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数,优化给药方案,设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式,CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发,在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物,适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上,结合病人个体特征,以1,2个血药浓度作为反馈,即可拟合估算个体药动学参数,优化给药方案结论经初步应用,CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

More than 3% of all deaths seem to be caused by adverse reactions to medical drugs, according to new research.

根据最新研究报导,有超过3%的死亡是由于药物副作用引起的。

We all need to be concerned about proper use of these drugs.

我们都需要关注如何正确的使用这些药物。

At least two separate inhibitory actions on 5-HT3A receptors could be identified for propofol, whereas the enhancing action seen for the two related smaller phenol derivatives could no longer be detected. 5-HT-dependent and 5-HT-independent interactions could be distinguished for all three drugs.

异丙酚被证实对5-HT3A 受体至少有两种相互独立的作用,而在两种相关的较小分子的酚类衍生物中所看到的增强作用则不能被检测到。5-HT 依赖和5-HT 非依赖两种相互作用因为这三种药物而著称。

Here again, antibodies, proteins or drugs can be used to modify this immune response

同样的,抗体、蛋白质或药物可以用来改变这种免疫反应。

After he was tangled with those "counterculture" boys, he began to be indulged in drugs and drink.

他和那些"反传统文化"的家伙混在一起后,就迷恋上了吸毒和酗酒。

She wouldn't be standing in line waiting for you to order up more drugs.

就不会老老实实等着你给她下药了

All those on board will be treated with anti-viral drugs on arrival.

所有船上的人将被视为与抵达抗病毒的药物。

They also think that artemisinin-only drugs—which would not receive the subsidy—would then be priced out of the market.

同时不会资助青蒿素药品,这样会使青蒿素药品由于价格原因逐渐淡出市场。

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推荐网络例句

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场,你等着挨绳子吧!

Several theories about reigniting and extinguishing of the arc have been refered.

本文综合考虑了几种电弧重燃和熄灭理论。