查询词典 drugs

Objective:To discuss the good practice of therapeutic monitoring for antiepileptic drugs.

抗癫痫药物(antiepileptic drugs，AEDs)的治疗目标是控制发作而不引起不良反应[1]。

In clinical. acetylcholinesterase inhibitors reduce the breakdown of synaptic acetylcholine, have been modestly effective in improving the cognitive deficits of Alzheimer's disease.The goal of this work is to determine enzyme kinetics and mechanisms of acetylcholinesterase and butyrlcholinesterase inhibition by five cardiovascular drugs, lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride, and two benzodiazepines, diazepam and chlordiazepoxide hydrochloride. All drugs in this study are reversible mixed-type inhibitors of acetylcholinesterase and butyrylcholinesterase. The pKi values for acetylcholinesterase and butyrylcholinesterase inhibition by the cardiovascular drugs are linearly correlated with the molecular weights of the drugs with the slopes of 0.005 and 0.0021, respectively. Therefore, van der Waals' interactions between acetylcholinesterase and the cardiovascular drugs are stronger than those between butyrylcholinesterase and the drugs. This is probably due to a smaller active site gorge and a more significant peripheral anionic substrate binding site of acetylcholinesterase than those of butyrylcholinesterase.

本研究之目的系决定乙醯胆碱酯酵素和丁醯胆碱酯酵素被五种心脏血管药物lovastatin， simvastatin， amlodipine besylate， nifedipine、hydralazine hydrochloride和两种benzodiazepines：diazepam和Chlordiazepoxide hydrochloride的抑制作用之动力学及机转，这些药物都是乙醯胆碱酯酵素和丁醯胆碱酯酵素的可逆性、混合型之抑制剂，实验结果显示，五种心血管药物对於乙醯胆碱酯酵素及丁醯胆碱酯酵素抑制之pKi值和药物之分子量呈直线之关系，斜率分别为0.005及0.0021因此丁醯胆碱酯酵素，与心血管药物间之凡德瓦作用（van der Waals' ）比乙醯胆碱酯酵素与心血管药物间者弱，这可能原因是丁醯胆碱酯酵素之活性区域比乙醯胆碱酯酵素之活性区域更宽广，但丁醯胆碱酯酵素之周边阴离子区域不及乙醯胆碱酯酵素之周边阴离子区域者明显重要，由於五种心血管药物对於乙醯胆碱酯酵素和丁醯胆碱酯酵素抑制之pKi值存在著线性关系表示此种抑制作用系经过共同之反应机理。

The article 353rd first section second section as well as article 354th of Chinese new penal code fascicle 1997 emendation fascicule, stipulate separately that crime of taking drugs by Tempting, inciting, cheating the others; crime of taking drugs by forcing the others as well as tolerating other people to take drugs, these three accusation are all around the implement which revolving other people in the objective aspect to take drugs or be injected narcotics. The author calls it crime of taking drugs in this paper for the three kinds crime of luring other people to take drugs or the drug-injection for others.

我国1997年修订后的新刑法典分则第三百五十三条第一款、第二款、第三百五十四条分别规定了引诱教唆、欺骗他人吸毒罪、强迫他人吸毒罪和容留他人吸毒罪，这三个罪名在客观方面都是围绕他人吸食、注射毒品而实施的，笔者在本文中把这三种针对他人吸食、注射毒品的犯罪称之为吸毒型犯罪。

Article 47 The units using anesthetic drugs and the first class of psychoactive drugs shall arranged specialized warehouses or cabinets to store anesthetic drugs and the first class of psychoactive drugs. The specialized warehouses should be equipped with antitheft and warning devices; the specialized cabinets should have strong boxes. The specialized warehouses and cabinets should be locked with two locks and managed by two persons.

药品监督管理部门、卫生主管部门发现生产、经营企业和使用单位的麻醉药品和精神药品管理存在安全隐患时，应当责令其立即排除或者限期排除；对有证据证明可能流入非法渠道的，应当及时采取查封、扣押的行政强制措施，在7日内作出行政处理决定，并通报同级公安机关。

Results The highest drug use frequency was biguanide. There was 50.9% in the oral antidiabetic drug combination. Leading the first 3 places on the list of drug combination were sulfonylureas in combination with biguanide, sulfonylureas in combination with α-Glycosidace inhibitor, biguanide in combination with α-Glycosidace inhibitor, while there was 16.1% in 3 kinds combination. When oral antidiabetic drugs were combined with other drugs, combination with antihypertensives drugs led the fist, while with antihypertensives drugs led the second.

结果 二甲双胍使用频率最高，口服降糖药联合用药的比例高达50.9%，居前3位的依次是磺脲类＋双胍类、磺脲类＋α-葡萄糖苷酶抑制剂和双胍类＋α-葡萄糖苷酶抑制剂，而3种以上口服降糖药联合用药的比例也达16.1%；口服降糖药与其他药物联合使用情况看，配合使用抗高血压药的频率最高，其次是降脂药。

Pharmaceutical excipients were used as a vehicle of water-soluble, liposoluble and even indissolvable drugs with low toxicity and satisfactory biocompatibility. Furthermore, it provides direction and method to decrease efflux of cytotoxic drugs from the cancer cells, promote the effect of clinical therapeutic efficacy, recover the sensitivity of the cancer cells to the cytotoxic drugs, and improve the characteristics of pharmacokinetics of some drugs such as increasing the absorption of some orally drugs, decreasing the renal clearance and hepat-clearance.

此外，通过抑制P-gp的外排功能，一些药用辅料具有逆转肿瘤细胞多药耐药的作用，为临床提高抗肿瘤药物的疗效，减少肿瘤细胞对药物的外排，提高其对药物的敏感性，提供了研究方向和试验手段。

The medicine enters sells saves the management system management system but to develop for the solution above question, this system mainly aims at the small hospital and clinic's medicine purchase, the sale, keeps in stock the link, the system may realize the drugs to go into storage function and so on management, drugs leaves storehouse management, adjusts prices management, inventorying management, finance information management, drugs information management, system maintenance, may facilitate completes each item of drugs attribute, the sales condition, the supply and demand condition statistics, causes each work the organization to be standarder.

医药进销存管理系统为解决上述问题而开发，本系统主要针对小型医院和卫生所的医药采购、销售、库存环节，系统可以实现药品入库管理、药品出库管理、调价管理、盘点管理、财务信息管理、药品信息管理、系统维护等功能，可以方便的完成各项药品属性、销售状况、供需状况的统计，使得各项工作的组织更加规范。

Diet-controlling and movement for weight-reducing are the utmost method for the therapy of NAFL. The therapy of protection of liver function is very necessary: diammonium glycyrrhizinate and Fufangdanshen as basic drugs and tiopronin as main drugs. We should be prudent to use sugar-reducing drugs. And we shouldn't advocate to use fat-reducing drugs routinely.

控制饮食和运动以减肥是治疗NAFL的首要措施；保肝治疗非常必要，甘草酸二铵和复方丹参作为基本用药，硫普罗宁或还原性谷胱甘肽作为必选药物；慎用降糖药物，不提倡常规使用降脂药物。

On the past few days, two nations with large numbers of AIDS-infected people have announced plans to distribute a triple cocktail of life-prolonging antiretroviral drugs free to all who need it.

在过去几天中，拥有大量爱滋病感染者的两个国家，中国和南非，都宣布它们计划免费将治疗艾滋病的三联鸡尾酒药品（a triple cocktail of life-prolonging antiretroviral drugs）发放给那些有求的人们，这种药品能够抵抗逆转录病毒，从而延长患者的生命。

On the past few days, two nations with large numbers of AIDS-infected people have announced plans to distribute a triple cocktail of life-prolonging antiretroviral drugs free to all who need it.

在过去几天中，拥有大量艾滋病病感染者的两个国家，中国和南非，都宣布它们计划免费将治疗艾滋病的三联鸡尾酒药品（ a triple cocktail of life-prolonging antiretroviral drugs）发放给那些有求的人们，这种药品能够抵抗逆转录病毒，从而延长患者的生命。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。