查询词典 drug-habit

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Moreover,if the drug is in the anhydrous state,the rate of dissolution is usually faster than with the hydrous salt.

而且，如果药物在无水状态，溶解的速度通常快速比与含水盐。

Aniline: One of the most important organic bases, parent substance for many dyes and drug s.

苯胺：一种重要的有机碱，是制造染料、药物的主要物质。

Methods The samples were identified by FORTUNE.2000 of Fuxing Company and automatic animalcule identification system of Zhuhai Heima Bioengineering Co., Ltd. The drug sensitivity was tested by disk diffusion methods.

菌株鉴定采用复星公司FORTUNE.2000和珠海黑马生物工程有限公司全自动微生物鉴定系统，药敏试验用纸片扩散法。

Aim To identify the drug-metabolizing enzymes involved in the hydroxylation of the new anti-inflammatory and anodyne imrecoxib.

目的 探讨新型抗炎镇痛药艾瑞昔布在人体内的羟基化代谢酶。

You go to the drug store for ibuprofen and antacid, not condoms and pregnancy tests.

到药店买的是消炎镇痛药和治胃酸的药，而不是套套和验孕纸

Patients had been advised to stop any antacid drug treatment at least 4 weeks before endoscope.

Hp阳性的19例患儿均为活动性胃炎，Hp阴性的17例患儿中有1例为活动性胃炎。

However, it may still be possible to antagonize the drug.

这时，仍有进行对抗的可能。

It is concluded that Compound A, the C. yunnanense extract, has notable anthelmintic effect and less toxin side effect and is expected to being developed into a new anti-A scans suum drug in the future.

云南贯众提取物化合物A对猪蛔虫病有较好的驱虫效果，且毒副作用小，有望开发成为一种新的驱蛔虫药。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷