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Further study the molecular character of tumor stem cells, and explore the mechanism of drug resistance.

深入的研究干细胞的分子特征、初步探索其耐药的机制。4。

The application of the capillary electrophoresis chemiluminescence detection in drug analysis was discussed.

本文对毛细管电泳化学发光法在药物分析中的应用予以综述。

Background and objective The drug resistance to chemotherapeutics is one of the important causes of low survival rate of lung cancer patients.

背景与目的肺癌细胞对化疗药物的耐受是肺癌患者生存率低的重要原因之一。

So it is of important significance for human health to explore a sort ofeffective treatments for cancers,to improve drug sensitivity for cancer cells and to reducenegative effects of chemotherapeutics.

因此，探索有效的肿瘤治疗方法、提高肿瘤对化疗药物的敏感性以及减小化疗药物的毒副作用，对保障人类健康具有重要的意义。

Methods: Consult VP diagnosis standard of American psychiatry institute what WHO promulgated, we chose 80 VD sufferer. We adopt study method of random and comfort drug comparison, both blind method to dose and front and bank of oneself chiasma test. We chose MMSE and ADL to evaluate curative effect through comparing Statistic mark before cure and after cure. Results: We had treated 72 VD sufferer on Jiannaoyizhi capsule. In these patients, there are 15 obvious efficiency, 38 efficiency and 19 inefficiency. The total efficiency is 73.61%. It has obvious reform action on cognizing obstacle and behavior.

参照WHO公布的美国精神病学会VD诊断标准入选VD患者80例，采用随机安慰剂对照，双盲给药，自身前后交叉试验的研究法，选择简易智能量表、日常生活自理能力量表于疗程前后统计分值变化进行疗效评估石结果：健脑益智胶囊治疗VD患者72例，显效15例，有效38例，无效19例，总体有效率73.61%，对VD患者的认知障碍和行为均有明显改善作用，其效应明显优于安慰剂(P.05)。

Because corticosteroid can modify the immunological process which is considered the major mechanism involved in AHS, it is used to treat AHS clinically. However, corticosteroid therapy may have deleterious effect (e.g., delayed healing of cutaneous lesions, infections, prolonged hospital stay). Therefore, the use of corticosteroids for AHS remains controversial. We reported a 54-year-old man who had underlying diabetes mellitus with chronic renal insufficiency, hypertension and hyperlipidemia. Allopurinol 100mg twice a day was initiated one month prior to admission. After taking the drug for 24 days, he developed a generalized mild itchy eruption on the trunk and upper extremities followed by chillness, fever, ocular discomfort and painful oral ulcer over one-week period and was admitted to the hospital. A skin biopsy revealed changes consistent with Stevens-Johnson syndrome.

本文报告一位54岁的男性患者，有高血压、高血脂、糖尿病及慢性肾脏功能不全的病史，最近发现有高尿酸血症(11.1mg/dL)而开始服用Allopurinol，在服用24日后，因为逐渐发生皮肤红疹搔痒、口腔溃疡、发烧、畏寒以及眼睛不适，一周之后到医院就医，经诊断为服用Allopurinol所造成之史帝文森－强生症候群(Stevens-Johnson syndrome)，因而在皮肤科住院接受治疗，由於病人有高血压、高血脂及糖尿病，所以入院后仅以支持疗法，并未给予全身性类固醇，然而病人之病况恶化，并有肾功能恶化，因而於住院两日后，转进肾脏科病房，在使用全身性类固醇治疗之后，病况持续改善，并在2周后出院。

By 2020, the majority of drug research and development and testing, may have been through computer simulation, or directly in the "chip in" to carry out.

到2020年，大部分药物的研发和试验，可能已经可以通过计算机仿真或是直接在"芯片里"进行。

As stereochemistry in drug molecule governs its biological activity, chirality is emerging as a key issue in pharmaceutical research.

药物分子的立体化学决定了其生物活性，手性已成为药物研究的一个关键因素。

This study demonstrates that a steady α-chloralose anesthesia can be achieved for fMRI study, which can be utilized in the study of drug, lesion or other brain experiments.

在本实验中，我们测试并达到了稳定的α－氯醛醣麻醉，而这个方法将可以应用在其他相关的实验上。

As the doctors point out, Chloramphenicol is a nasty drug.

正如医生指出的那样，氯霉素是一个让人讨厌的药物。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。