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Methods: We collected 121 of clinical isolates of Enterobacter, including 87 isolates Enterobacter cloacae, 34 isolates Enterobacter aerogenes, all of the isolates were detected by cefoxitin three-dimension test, drug resistance phenotypes estimation, cloxacillin disc synergy test and cloxacillin-potentiated disc diffusion test respectively to find high-level AmpC β-lactamase isolates, drug resistance phenotypes estimation were also used to detected high induction producing AmpC β-lactamases isolates, meanwhile, we took three-dimension test as standard method, and compared to other methods, then calculated the coincidence rates, sensitivities and specificities of them.

采用头孢西丁三维实验、纸片耐药表型推断法、邻氯西林纸片协同法、双纸片邻氯西林增效试验分别检测高产AmpCβ-内酰胺酶株,获得高产AmpC酶在肠杆菌属细菌中的表达状况。采用纸片耐药表型推断法检测诱导和高产AmpC酶,同时以头孢西丁三维实验为标准,其他三种方法与之相比较,分析它们检测高产AmpC酶的符合率、灵敏度和特异性。

"Apraclonidine, a selective alpha-2-agonist, was developed to lower intraocular pressure and minimize the systemic side effects associated with the use of its parent drug, clonidine," write Patrick Watts, MBBS, MS, from the University Hospital of Wales in Cardiff, United Kingdom, and colleagues."An investigation of the site of action of apraclonidine incidentally uncovered a reversal of anisocoria in patients with absent sympathetic innervation of one pupil due to its alpha-1-effect on a pupil with denervation supersensitivity.... The easy availability of apraclonidine, its mild alpha-1-agonist activity, and its hitherto benign safety profile has encouraged its use as a first-line drug in the diagnosis of oculosympathetic paralysis."

英国加地夫市威尔斯大学附设医院的外科学硕士Patrick Watts及研究同仁指出,Apraclonidine是一种选择性的α-2-拮抗剂,是用来降低眼内压,并减少其母系药物降保适使用上的相关全身性副作用;在一项针对apraclonidine作用位置的研究中,因其单侧瞳孔神经切除之α-1-效应,而附带提出单侧瞳孔无交感神经支配患者之瞳孔大小不等为可逆转,apraclonidine之高可利用率,其轻微的α-1-拮抗活性,以及迄今良好的用药安全档案,更强化其作为视交感神经瘫痪诊断第一线药物的使用率。

OBJECTIVE To study the inhibitory effects of diterpenoid compound ( drug A.drug B) isolated from Annona glabra Linn on the proliferotion of SMMC-7721 cells lines and its mechanism .

目的 研究光叶番荔枝中二萜类化合物药A-kaur-16-en-19-oic acid、药B-kauran-19-al-17-oic acid对人肝癌细胞株SMMC-7721的抑制作用及其机理。

Antituberculosis treatment is complicated by frequent drug-interactions with highly active antiretroviral therapy and adverse drug reactions are more common among HIV-infected patients.

抗结核药物与高效抗逆转录病毒药物的副作用及时常发生的相互作用使得HIV-TB合并感染的治疗更趋复杂化。

Abstract] Objective To study the curative effect on atrophia nervi optici treated by Chinese crude drug and meridian method.Methods Selfmade Chinese crude drug was used combined with meridian injection method and Western medicine for promoting microcirculation by mouth in order to improve activeness of cellula nervosa.

采用自制研究的中药1、2、3号活血化瘀药剂,口服改善视神经组织的微循环同时配合肝、肾俞药物注射经络调整神经细胞膜活跃性改善其传递介质的通透性。

RESULTS Among 327 specimens, cultures were positive in 320(97.9%),included 328 aerobe strains and 436 anaerobe strains.Most of the pathogenic bacteria were Gram negative.In aerobes,E.coli was the first (176 strains),while bacteroides were the first(216 strains) for anaerobes. In the positive cases, aerobic and anaerobic mixed infection were 64.7% while unitary aerobic and unitary anaerobic infection were only 25% and 10.3%, respectively.The drug sensitive rate of aerobes to the third generation cephalosporine was exceed 90%.The drug sensitive rate to metronidazole was 97.9%.

结果 32 7例标本中 32 0例有细菌生长,其中需氧菌 32 8株,厌氧菌 4 36株,以 G-菌为主;在需氧菌中以大肠埃希菌为主,占 176株;厌氧菌中以类杆菌属为主,占 2 19株;大多数为需氧菌和厌氧菌的混合感染,占 6 4 。7%;单纯需氧菌和单纯厌氧菌感染分别占 2 5 %和 10 。3%;需氧菌对第三代头孢菌素的敏感率在90 %以上,厌氧菌对甲硝唑的敏感率在 97.7%。

Drug mule (More Chinese women duped to bedrug mules--Foreign drug traffickers are duping an increasing number of Chinese women, especially young victims, into carrying drugs into China, the General Administration of Customs has said.

更多的中国妇女受骗成&毒骡&——海关总署表示,越来越多的中国妇女,特别是年轻女子,受外国毒贩的诱骗后将毒品带进中国。

Drug muleMore Chinese women duped to bedrug mules--Foreign drug traffickers are duping an increasing number of Chinese women, especially young victims, into carrying drugs into China, the General Administration of Customs (GAC has said.

更多的中国妇女受骗成&毒骡&--海关总署表示,越来越多的中国妇女,特别是年轻女子,受外国毒贩的诱骗后将毒品带进中国。

F$ p '毒骡 drug muleMore Chinese women duped to bedrug mules--Foreign drug traffickers are duping an increasing number of Chinese women, especially young victims, into carrying drugs into China, the General Administration of Customs (GAC has said.

更多的中国妇女受骗成&毒骡&——海关总署表示,越来越多的中国妇女,特别是年轻女子,受外国毒贩的诱骗后将毒品带进中国。

Clinical therapy to skin lesion could be treatedby systematic or typical application while drug concentration in skin lesion should beknown in both conditions, such as the drug concentration in blood should be knownwhen the pathogenesis of skin disease is some systematic factor.

其中药物与受体之间的亲和力由药物的结构和理化性质决定,因此靶组织的药物浓度是调节药物药效作用的主要手段。

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