查询词典 drug-addicted

To prevent the accumulation of intracellular drug with efflux pumps is one of the means of producing drug resistance.

其中由细菌排出泵介导的阻止药物在体内积累是产生抗性的重要手段之一。

Multiple blood samples were taken for measurement of the time course of the drug concentrations, and the electrocorticogram processed (approximate entropy, for propofol and methohexital and percentage high frequency time, for ketamine) to numerically quantify drug effect.

结果：使用药代/药效分析法得出的t1/2Keo：氯胺酮为2.0±0.4min，异丙酚为2.7±1.1min，而美索比托的t1/2Keo为0.3±0.1min明显较前两者缩短。药代/药效分析法和总体守恒分析法在药物到达峰值的时间举无明显差异。

Results: The prepared AmB-PBCA nanoparticle had a regular spherical or elliptic surface, with a mean diameter of (69.01±28.56) nm. The curve of standard AmB was linear within the range of 1.12-5.60μg/ml: D405=0.1634c+0.0066 (r=0.9993). The average recovery of AmB-PBCA-NP was 99.93%, showing the solution of AmB-PBCA-NP was stable within 12 h. The nanoparticles showed a sustained drug release in vitro within 24 h. The optimized recipe was: DextranT-70 stabilizer without sodium deoxycholate, with a mean encapsulation rate of 56.10% and a drug loading rate of 82%.

结果：制备的AmB-PBCA-NP外观呈圆或类圆形，平均粒径(69.01±28.56)nm，分散均匀；AmB标准品在1.12~5.60μg/ml范围内的线性回归方程为：D405=0.1634c+0.0066，r=0.9993，AmB-PBCA-NP的平均回收率为99.93%，其溶液在12h内稳定性较好；体外释放实验表明24h体外释放具有一定的缓释性；实验发现最优化的处方为稳定剂采用DextranT-70，且不加助溶剂脱氧胆酸钠，其包封率及载药量均比较高，分别为56.10%、82%。

Methods Use VB program language and Access database to make management system of narcotic drug in drugstore, including prescription register, patient record, empty ampoule management, medicines reclaiming record and etc. By inquiring we can export the EXCEL file made up of narcotic drug related management documents.

利用 Visual Basic编程语言和 Access 数据库编制门诊药房麻醉药品管理系统，进行麻醉药品的处方登记、患者资料、空安瓿和剩余药品回收等管理工作，通过查询导出 EXCEL 表，生成麻醉药品相关管理文件。

Results Stable drug-resistant SW1990/GZ cell strain was established by culturing with gemcitabine for 9 months. The morphology and growth characteristics of the cell strain changed remarkably. The cells shrinked and became rounder; its endoplasm expanded; granular substances increased; and the doubling-time was prolonged. Resistance of the cell line to gemcitabine, fluorouracil, adriamycin, and mitomycin significantly increased. The TrxR activity of the drug-resistant cells was increased markedly.

结果 药物培养9个月后，得到稳定传代的SW1990/GZ耐药细胞株；其形态学、生长特征等均发生了明显变化，细胞变圆、体积缩小、内质网扩张、颗粒样物质增多及细胞倍增时间延长；对吉西他滨、5-氟尿嘧啶、阿霉素和丝裂霉素的耐药性均显著增加；耐药细胞的TrxR活性也明显增高。

In case of the drug, the drug loading contents was 18.6% and entrapment efficiency was 52.2%.

在这种情况下给药，药物的负荷容量为18.6％捕获率为52.2％。

RESULTS: Biomaterial vector which were used to coated insulin could prevent insulin degradation by erepsin and enhance insulin stability. In addition, biomaterial vector benefited for uptake and transport of intestinal tract mucosa to insulin, target-control of drug release, enhancement of drug bioavailability, and establishment of insulin release velocity style for human physiological drive so as to realize sustained release of insulin.

结果：以生物材料作为载体包埋胰岛素，可避免胰岛素被胃肠蛋白酶降解，提高其在胃肠道内的稳定性，并有利于肠道黏膜对胰岛素的摄取和转运，在人体内递药过程中又能实现靶向控制药物释放，提高药物的生物利用度，满足人体生理需求的胰岛素的释放速率模式，实现了胰岛素的持续释放。

There were also 6 treatment courses combined the contraindicated drugs, such as carbamazepine, ergonovine and rifampin. Approximately 20% of AEs (21/105) might be associated with drug-drug medicines.

在voriconazole治疗期间并用最多的潜在交互作用的药品为prednisolone（16/105，15.2%），但仍可能并用到配伍禁忌的药品（6/105，5.7%），例如：carbamazepine、ergonovine、rifampin。

Objective To investigate the general pattern and characteristics of the adverse drug reactions associated with Erigeron injection in order to guide rational drug usage.

目的 探讨灯盏细辛注射液所致不良反应的一般规律及特点，指导临床合理用药。

"This is an important point," Dr. Sawyers told Medscape in an interview,"as it shows that the drug target continues to mutate and that BCR-ABL is the escape mechanism." Hence, further drug development should continue to focus on BCR-ABL and not on any of the other mechanisms that are thought to also be involved, he commented.

Sawyers医师在一项访谈中向Medscape表示，这是个重点，当这项研究显示药物的标的持续在突变，且BCR-ABL基因有逃脱机转，他评论，之后的药物研发应该继续针对BCR-ABL且不应针对其他被认为牵涉其中的机转。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！