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These results are showed that ERCC1 is the important part of human nucleotide excision repair system, which is relevant to drug resistance of ovary and the alimentary canal tumors.

ERCC 1是人类核苷酸切除修复系统的重要组成部分,其表达水平与卵巢肿瘤、消化道肿瘤的耐药性有关。

After two to three days of usage, the diuretic effects of this drug decline because of increased downstream reabsorption of ions and water by the renal tubules; however, the alkalinization of urine persists, and this basic urine attracts weak acids such as uric acid and cystine into the urine, thus increasing their urinary excretion.

在使用两到三天之后,这种药物利尿的效果会下降由于增加了下游肾小细管离子和水再吸收;然而,坚持碱化尿,而这种基本的吸收了弱酸例如尿酸和胱氨酸到尿里,因而增加了尿的排泄

Methods: from prepation of crude drug as start, study the technology of extract and defat with L9 (3~4) orthogonal test. With EtOH extraction and water sed, alkali washing, EtOAC extraction as main methods of eliminate dopant. Finally with alky AlzO3 chromatographic column, rich and gain anticancer active site. The maximum response was achieved at a 40 min extracting time with 10 times volume 90% EtOH added to the sample for the first time and 30 min for the second time. Adding 10 times water will produce precipitation; Place the precipitation into 6 times petroleum benzin to de-fat at 60℃.

云南红豆杉中抗癌活性物制备工艺研究方法:利用正交设计试验L9(3~4)确定原料药提取工艺为:10倍量90%乙醇提取两次,第一次40分钟,第二次30分钟;醇提液用10倍量水沉;沉淀加6倍量石油醚40℃脱脂;用1mol/L的NaOH溶液碱洗,除去酸性杂质;以碱性氧化铝柱,以环己烷/丙酮为洗脱溶剂,在环己烷-丙酮(6:4)段富集到所需活性部位,洗脱剂用量为3VB。

Unfortunately, we have had to deal with all of the above, and worse, have actually had at least one death on the premises from a drug overdose.

不幸的是,我们不得不处理所有上述情况,并更糟的是,实际上已经有至少一人死于吸毒过量。

The re was no infection after allopathy treatment without ceasing drug. Conclusion: The most of side effects were mild and convertible.

治疗剂量注射液的不良反应多为轻度,针对其不良反应进行对症护理,同时加强相关的健康指导,可保证化疗的顺利完成。

Result: Most of the 18 patients were observed with mild reactions and they could recovered after ceasing the arsenic treatment or allopathy. There was no infection after allopathy treatment without ceasing drug.

结果:本组18例患者在治疗过程中,大多出现了不同程度的不良反应,如:水钠潴留、胃肠道反应、皮肤干燥、肝功能损害等,但程度均较轻,一般无需停药,给予适当的支持治疗和护理后症状缓解,继续治疗。

Result: Most of the 18 patients were observed with mild reactions and they could recovered after ceasing the arsenic treatment or allopathy. The re was no infection after allopathy treatment without ceasing drug.

结果:本组18例患者在治疗过程中,大多出现了不同程度的不良反应,如:水钠潴留、胃肠道反应、皮肤干燥、肝功能损害等,但程度均较轻,一般无需停药,给予适当的支持治疗和护理后症状缓解,继续治疗。

Modification of the side chain radical of β-lactam class antibiotic is a possible effective way,while the mother nuclide maintain the activity, but the different side chain radical alternating the drug tolerance of bacterium.

改造β-内酰胺类抗生素的侧链,不同侧链改变了细菌的耐药性,而其母核仍保持抗菌活性,这可能是克服抗生素使用剂量不断增大的一条有效途径。

It's offending to the middle class, because it means that they can no longer blame the problems on superficial aspects such as "too much TV,""Americanization" or drug dealing.

"它的得罪,以中产阶层,因为这意味着他们再也不能归咎问题,对皮毛方面的,如"太多电视","美国化"或"毒品交易。

A typical drug aminopyrine, in addition to levamisole, semi-synthetic penicillin may also cause.

典型药物是氨基比林,此外左旋咪唑、半合成青霉素也可引起。

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场,你等着挨绳子吧!

Several theories about reigniting and extinguishing of the arc have been refered.

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