查询词典 drug-addict

To facilitate the applications of biologically functional protein in drug design, it is necessary to have a thorough understanding of their conformations and their interactions with the receptors. NMR spectroscopy has the unique ability to retrieve information about 3D structures of proteins and their interactions with the target proteins in solution. Many NMR techniques have been used to study a number of pharmaceutically important proteins and characterize their interactions with the targets. In this review, we will introduce these NMR methods and show how to utilize them for protein drug design.

为了设计具有生物功能性的蛋白质来当作药物，我们必须对其蛋白质结构与其受体在结合时的作用有完整清楚的了解，而核磁共振光谱具有独特的能力，可以获得溶液状态下蛋白质结构以及蛋白质与标的蛋白质交互作用间的资讯，目前已有许多核磁共振光谱技术运用到蛋白质药物的研究，并确认它们与其标的蛋白质间的作用模式，笔者将在本文中介绍这些技术，以及如何运用它们来获取重要资讯，俾设计蛋白质药物。

This drug must have a dual purposes on cure and prevention, so the selection of pharmacokinetical and pharmacodynamical functional group should be prior to endogenous substances in human body, and the drug should have the feature of low poison.

铅中毒是一种严重危害人类健康的疾病，它对机体的损害早在出现临床症状以前已经存在，从而提出了亚临床症状性铅中毒的概念。

In the preformulation studies, UV absorption characteristics, solubility and stability of the drug in the different media were determined, the physico -chemical compatibility between the drug and nine kinds of excipients was observed using DSC analysis.

在处方前研究中，对盐酸尼卡地平的紫外吸收特性、不同介质中的溶解度和稳定性进行了测定，并利用DSC法考察了该药物与九种辅料（EC，HPMC，PVP，PEG6000，MCC，乳糖，淀粉，硬脂酸镁，SLS等）间的物理化学相容性。

The main three parts of the present study are: the preformulation study involving screening the proper enhancers for transdermal aborption of α-asarone;Formulation study and developing a drug-in-adhesive transdermal patch of α-asarone using Eudragit E100 as pressure sensive adhesives;The α-asarone reservoir patch was prepared using 1 %HPMC of ethanol solution as medium and EVA membrane for controling the release of drug, and do the research its bioavailability.

主要内容有以下三个方面：药物经皮吸收制剂开发的处方前研究工作；采用Eudragit E100为压敏胶材料，进行了α-细辛醚胶粘剂分散型贴片的研究；以1%的HPMC的醇性溶液为储库介质，以EVA膜为控释膜，进行了α-细辛醚储库型贴片和生物利用度的研究。

Targets and methods: Shanghai psychological counseling centers for treatment in patients with SAD voluntary CBGT, meet DSM-IV diagnosis of SAD standards, sex irrespective of age; Records of the patients general information and history information, including advisory, name, sex, age, occupation, culture, marriage, family history, course of illness, age of onset, inducing factor, premorbid personality, grandfather, and so on and treatment of MMPI; participate in group therapy treatment of SAD during the treatment of SAD did not take drugs, If that is used to the drug subject to a two-week drug washout period. Six cases of sleep well at night before bed without taking regular small doses of drugs Zhumian stability.

对象和方法：上海市心理咨询中心就诊的SAD患者中自愿参加CBGT者，符合DSM-IV关于SAD的诊断标准，性别年龄不限；记录患者的一般资料及病史资料，包括咨询号、姓名、性别、年龄、职业、文化、婚姻、家族史、病程、起病年龄、诱发因素、病前性格、既往治疗情况等及MMPI测试；参加集体治疗的SAD者治疗期间均未服用治疗SAD药物，如即往用过药者需经两周的药物清洗期，其中6例因睡眠不好于夜间睡前不定时服用小剂量安定类药物助眠。

the application of drug and management are rationable the whole,while it still exists some problems. clincian and pharmacist need to study the pharmacy knowdeges to reduce the irrational drug.

我院处方用药和管理基本合理，但也存在一些问题，医师和药师应共同学习，减少不合理用药。

At high drug concentrations, the amount of bound drug approaches an upper limit depending on the number of available binding sites, resulting in saturability.

药物浓度高时，因蛋白可结合部位数目的关系，结合药物量接近上限，导致饱和性。

Mexican troops arrested a leader of the Sinaloa drug mob, following a fortnight of armed clashes in the north of the country between the army and drug-traffickers.

被拘捕 Sinaloa 暴民的一个导杆，跟随在军队和毒枭之间的国家北方的一个两星期的武装冲突的墨西哥的军队。

It is the time to final time limit on one hand already not much , it is on the other hand according to " drug law " regulation , begin to carry out national bureau and provincial bureau by the form of a drug of category of medicines and chemical reagents two class attestation , facing onerous working job and new situation , must sturdy confidence is strong the job , cogent according to " uniform standard , standard is supervised , assure quality , stimulative development " principle , ensure the program goal that achieves GM P of medicines and chemical reagents on schedule , safety of sponsorial civil medicine is effective .

一方面是到最后时限的时间已经不多了，另一方面是按照的规定，开始按药品类别剂型实施国家局和省级局两级认证，面对着繁重的工作任务和新的形势，必须坚定信心扎实工作，切实按照&统一标准，规范监督，保证质量，促进发展&的原则，确保按期实现药品GMP的规划目标，保证人民用药安全有效。

Nov. 2002. Purpose of the research By knowing HIV related high-risk behaviors of drug users and related social and cultural factors, it is to provide a concrete, and socially and culturally appropriate suggestions so as to establish HIV/AIDS prevention stratege for the drug users treatment center in Gansu Province.

研究目的认识戒毒所中吸毒人群与HIV感染有关的危险行为和危险因素以及相关社会文化环境，为在甘肃省戒毒所中建立HIV预防模式提供具体的、符合实际的、并从社会文化意义上适当的建议。研究意义一。本研究的应用意义 1。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！