查询词典 doxorubicin

The cell cycle and apoptosis and the expression of P-pg, bcl-2, P53 in the MG63 and MG63/R cell lines were analyzed by flow cytometry. Results The resistance index of the MG63/R cells to cisplatin was 83.557±4.841. The cells also had resistance to doxorubicin, vincristin, methotrexate and cyclophosphamide. Disordered structure of the MG63/R cells was observed through microscopy. The cells appeared in triangle, polygon and polynucleation. The increase of granular endoplasmic reticulums and apophyses was observed through transmission electron microscopy. The proliferation ability of MG63/R increased significantly, with a low apoptosis index.

结果 经顺铂186d的诱导，建立了MG63/R，其对顺铂的耐药指数为83.557±4.841，对阿霉素、长春新碱、氨甲基蝶吟、环磷酰氨亦产生不同程度的交叉耐药；光镜观察可见MG63/R细胞排列不规则，形态呈三角形、多角形及多核现象；透射电镜显示MG63/R细胞表面突起增加，粗面内质网丰富；细胞周期分析显示细胞增殖能力明显增加而细胞凋亡明显降低；MG63/R细胞 P-pg、bcl-2阳性表达较MG63细胞明显增加，P53表达则明显降低。

FDA a roves doxorubicin, an anti-tumor antibiotic fromStreptomyces bacteria.

1974年， FDA批准一种来源于链球菌的抗肿瘤抗生素-阿霉素。

Objective To study the effect of the proliferation about HepG2 cells were treated by aloe-emodin, doxorubicin alone and both of them in vitro.

目的 体外观察芦荟大黄素、阿霉素单用及联合应用对人肝癌HepG2细胞增殖的影响。

Results when treated with aloe-emodin or doxorubicin for 48h, with the increase of drug concentration, the growth inhibition rate increased.

结果 两药单独作用48 h对HepG2细胞的抑制率，随着药物浓度的增加均相应增加，呈剂量依赖性。

Objective To evaluate the efficiency and safety of liposomal doxorubicin in the treatment of recurrent epithelial ovarian cancer.

目的 评价脂质体阿霉素在复发性卵巢上皮性癌二线化疗治疗中的有效性和安全性。

Abstract］ Objective To evaluate the efficiency and safety of liposomal doxorubicin in the treatment of recurrent epithelial ovarian cancer.

摘要］ 目的评价脂质体阿霉素在复发性卵巢上皮性癌二线化疗治疗中的有效性和安全性。

Neoadjuvant chemotherapy with low dose of pegylated liposomal doxorubicin plus weekly paclitaxel in operable and locally advanced breast cancer.

新辅助化疗法联合低剂量聚乙二醇脂质体多柔比星及每周一次紫杉醇在可行手术的局部进展期乳腺癌中的治疗。

Half the women received a combination therapy of trabectedin and a chemotherapy drug called pegylated liposomal doxorubicin.

一半的女性接受trabectedin和称为脂质体阿霉素聚乙二醇的化疗药物组成的混合疗法。

In second-line drugs for the treatment of recurrent epithelial ovarian cancer,liposomal doxorubicin is more effective and well tolerated.

脂质体阿霉素在复发性卵巢上皮性癌二线化疗药物中有较高的疗效优势，且具有更好的安全性和可耐受性，楷莱可作为复发性卵巢上皮性癌非铂类化疗的理想选择。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。