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Canine distemper during the first heat in the high doses of hyperimmune serum, can enhance the body enough antibodies to prevent clinical symptoms, therapeutic purposes.

在犬瘟热最初发热期间给予大剂量的高免血清,可以使机体增强足够的抗体,防止出现临床症状,达到治疗目的。

Methods:The EAE in Lewis rats was induced by giving hypodermal injections in feet with spinal cords homogenate of guinea pigs; The histological changes were observed under light microscope, then changes of incidence rate、latency、clinical symptoms and histology of EAE which were effected by idazoxan with different doses were compared by method of quantization.

采用豚鼠全脊髓匀浆脚垫皮下注射,免疫Lewis大鼠复制EAE模型,采用量化评分法,比较不同剂量组咪唑克生对EAE发病率、潜伏期、临床症状和组织学的影响。

MethodsUnder the conditions of constant temperature, constant humidity, auto-light and electromagnetic shielding, we gave experimental rats suanzaoren decoction at different doses and adopted chronicity electrode embedment technology to trace the EEG of hypodermal layer of freerunning rats , which rececived electric stimulation.

方法在恒温、恒湿、自动光控及电磁屏蔽条件下,给予实验动物不同剂量酸枣仁汤,采用慢性电极埋植技术描记电刺激所致失眠大鼠自由活动情况下的皮层脑电图。

Results 4 patients in the 5 patients were treated with interferon or nucleoside analogue else at the same time of taking telbivudine ;1 patients took multiple doses of telbivudine ; their clinical presentation are all muscular soreness 、general hypodynamia; one case presented myocardium injury, three cases presented nerve damage.The serum creatine kinase elevated.

结果 5例病人中,有4例合并应用干扰素或其它核苷类似物,1例服用剂量加倍;临床均表现为肌肉酸痛,全身乏力;心肌受累者1例;有神经损伤者3例;血清CK水平升高,临床误诊率高。

At the one-cell stage, each embryo was injected with gradient doses of 2-8ng MO. The control morpholino, was purchased from Gene-Tools.To test the knockdown effectiveness of the morpholino, the tbx2-EGFP (enhanced green fluorescent protein) construct was generated. And coinjection of morpholino with mRNA tests its specificity of the morpholino. Overexpression of tbx2 via mRNA microinjection helps us understand gaining function of tbx2. Results The tbx2-EGFP construct tests the knockdown effectiveness of the morpholino. Zebrafish embryos lacking tbx2 function have defects in cardiac contractility, rhythm and morphology in a dose-dependent manner. The embryos with c-MO are normal in development. Coinjection of morpholino with mRNA rescue the phenotype of tbx2 knocking down. The phenotypes include pericardial edema, hypogenetic ventricle, dilation of atria, arrhythmia, bradycardia, asystole, abnormal atrioventricular canal, aberrant valve and blood regurgitation.

结果荧光蛋白融合标记实验验证了tbx2-MO可以很好得阻抑斑马鱼胚胎tbx2的表达,tbx2-MO组胚胎在心脏收缩性、节律和形态学发生上出现了异常,心脏畸形随着注射剂量的增加而出现比较一致的表型,而c-MO组胚胎没有出现明显的畸形;tbx2-mRNA和tbx2-MO的共注射减少了tbx2-MO胚胎心脏畸形的发生率及减轻了心脏畸形的程度,验证了所设计合成的tbx2-MO对tbx2基因的抑制作用具有特异性;tbx2-MO组胚胎心脏缺陷包括心室发育不良、心房扩张、房室管和瓣膜异常以及心率缓慢、心律不齐、心脏停搏、血液返流等,并根据心脏发育异常的程度分为轻、中、重度畸形组tbx2-mRNA基因过表达胚胎没有见到心腔的形成。

The differences among these two hospitals are not ignorable, or the estimated doses effect will be biased.

同时,医院别间的差异亦不能忽略,否则推估出有偏差的剂量效应将是可预期的。

Therapy to the syndrome is very simple: dig a bunch of imperata, remove its skin, wash away the mud, and boil in a pot for about ten minutes. Drink it before meals after the boiled water is cool, so that urine can become clean and yellow tongue coating can disappear after taking one or two doses.

对症治法十分简单:去田野里挖白茅根一大把,去皮儿,洗去泥土,放人锅中水煮约十分钟,待水凉后饭前空腹喝之,往往一至二次小便即清而黄苔亦退。

When used for ADHD at recommended doses, the medications heighten concentration and diminish impulsivity and hyperactivity.

当用于多动症在推荐剂量下,药物浓度提高,减少冲动和多动。

It was observed that, at the doses of 50 mg/kg and 100 mg/kg, geniposide could significantly increase the biliary secretion after intraduodenal administration, while crocins showed no effect.

结果显示西红花苷50和100 mg/kg剂量均不增加大鼠的胆汁流量,而京尼平苷50和100 mg/kg剂量均可显著增加大鼠胆汁流量,降低胆汁内胆固醇含量,增加胆汁内HCO-3浓度,但对胆汁酸,胆红素,〔Ca2+〕含量无显著影响。

Aim To investigate the pharmacokinetics of rabeprazole after intravenous, intraportal and intraduodenal administration at various doses and to clarify the impact of hepatic and intestinal first-pass effects to bioavailability of rabbits.

目的 研究雷贝拉唑在大白兔体内经十二指肠、门静脉与外周静脉等不同方式及不同剂量给药时的药代动力学,并探讨肠道、肝脏首过效应分别对其生物利用度的影响。

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The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性,因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊,这是第二次你打败了我!

So a kind of strong antagonism permeated in the relations of two countries.

所以两国这一时期的政治关系始终弥漫着一种强烈的对抗情绪。