查询词典 dopamine

The plasticity of NSCs was detected by the differentiating test. HESCs were induced into dopaminergic neurons by means of adding Sonic Hedgehog Peptide and fibroblast growth factor eight (FGF8) early under the condition of mocked microenvironment and different development stage of dopaminergic neurons in vivo ,meanwhile made comparison with traditional method . The marker of dopaminergic neurons was tested by immunocytochemistry and RT-PCR, the content of dopamine and its derivation homovanillic acid were measured by HPLC-ECD.

模拟体内多巴胺神经元分化发育的不同阶段及微环境，采用早期添加音猥因子及成纤维细胞生长因子-8(FGF8)的方法，诱导hESCs定向生成多巴胺能神经元，并与传统的诱导方法相比较，免疫荧光细胞化学和RT-PCR法检测多巴胺能神经元的标志，高效液相色谱法检测诱导后细胞及细胞培养上清液中多巴胺及其代谢产物高香草酸的含量。

Methods The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 7-nitroindazole (7-NI) on nitric oxide synthase activity, levels of dopamine、3,4-dihydroxyphenylacetic acid、homovanillic acid, and TH-immunostained postive nerve fibres in the striatum of mice were determined by using colorimetic analysis, HPLC with electrochemical detection, and immunohistochemical analysis.

用比色分析、高效液相色谱电化学及免疫组化法检测1-甲基-4-苯基-四氢吡啶和7-硝基吲唑（7-NI）对C57BL小鼠纹状体一氧化氮合酶活性，多巴胺、二羟基苯乙酸、高香草酸水平和酪氨酸羟化酶免疫阳性神经纤维的影响。

In the pretreatment group, Bak Foong Pill extracts were given for 14 daya prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.

给予BFP预处理后，用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化；同时应用免疫组织化学法检测Bax蛋白表达；应用高效液相－电化学方法检测纹状体多巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。

Hours later,these mice were decapitated,and the striatums were isolated from thebrains. The levels of dopamine, serotonin ( 5-HT ), homovanillic acid, 5-hydroxyindoleacetic acid ( 5-HIAA ) andnorepinephrinein the striatum were measured by high-performance liquid chromatography with electrochemical detection.

给3组小鼠分别喂食Dieldrin 50 mg·kg-1体重、Dieldrin 40 mg·kg-1体重和等量的生理盐水，3 h后处死小鼠，取纹状体匀浆用高效液相色谱-电化学检测法测定纹状体中多巴胺、5-羟色胺(5-HT)、高香草酸、5-羟基吲哚乙酸(5-HIAA)和去甲肾上腺素的含量。

Xingpikaiyu Formula ; depression model ; neurotransmitter ; 5_hydroxytryptamine ; homovanillic acid ; dopamine

醒脾开郁方；抑郁模型；神经递质； 5-羟色胺；高香草酸；多巴胺

Serotonin (5-HT), its precursors tryptophan and 5-hydroxytryptophan (5-HTP), major metabolites 5-hydroxyindoleacetic acid (5-HIAA); and 3-methoxy-4- hydroxyphenylethylene glycol , homovanillic acid , the respective major metabolites of noradrenaline and dopamine were measured by a method of HPLC.

应用高效液相色谱法测定其中5—羟色胺（5-HT）系列代谢物：色氨酸、5-羟色胺酸（5-HTP）、5-HT、5-羟吲哚乙酸（5-HIAA）；多巴胺的主要代谢产物3-甲氧基-4-羟基苯乙酸；去甲肾上腺素的主要代谢产物3-甲氧基-4-羟基苯乙二醇等。

The concentration of β-EP in plasma in patients with VP decreased significantly,its mechanism might be relate to the decline of dopamine system's function induced by MCI of basal ganglion,lipid hyperoxidation and radical lesions in chronic cerebrovascular di-sease,abnormality of immune function,decrease of stress and inflammation reaction.

VP患者血浆β-EP含量明显降低，其机理可能与基底节区MCI导致多巴胺系统功能降低、慢性脑血管病脂质过氧化和自由基损伤、免疫功能异常、应激能力减弱和炎症反应有关。

In present study, levels of dopamine 〓 and 〓 receptors and expression of the protein mRNAs in striatum were exarmined by the methods of immuno- histochemistry and in situ hybridization, respectively. It was found that mice treated by paraquat taken orally for four months displayed a marked hypoactive behavior.

本研究以口服给予小鼠百草枯的PD模型，采用免疫组织化学、原位杂交结合计算机图像处理分析技术，观察百草枯对纹状体区多巴胺〓受体、多巴胺〓受体蛋白含量和基因表达的影响。

Parkinson's disease is a kind of a progressive neurodegenerative disorder, which is caused primarily by selective degeneration of dopaminergic neurons in the substantia nigra pars compacta. The symptoms of PD include tremor, hypokinesia, and rigidity, caused by the depletion of dopamine in the striatum.

帕金森氏症是目前临床常见的神经退化疾病之一，目前对於帕金森氏症的药物治疗，主要是额外提供多巴胺或增加脑内多巴胺的停留时间，以减缓患者的症状，然而这些治疗方法皆无法减缓多巴胺神经细胞的持续性退化。

Objective To study the counteraction of l-tetrahydropalmatine (1-THP) against bromocriptine-induced hypoprolactin in lactational rats and to prove that l-THP is an antagonist of dopamine D2 receptors.

目的 研究左旋四氢巴马汀(l-tetrahyoropalmatine， l-THP)对溴隐亭(Bromocriptin， Bro)诱导的哺乳期大鼠催乳素(Prolactin， PRL)水平低下的拮抗作用，以证实其为中枢多巴胺能D2受体抗剂。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了