查询词典 docking

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

In the evening, when Frank Heemskerk was met by Dalian Mayor Xia Deren, he expressed his appreciation for CCP TDL 's effort on helping to open this conference successfully and he would lead more Netherlandish enterprises to nvestigate on the spot, hold high-standard enterprises docking negociation and look after broad and deep-rooted cooperations for the future.

当日晚，荷兰外贸大臣亨斯科克在香格里拉大饭店与市长夏德仁会见时，对大连贸促会协助会议成功召开所做出的努力，向夏市长表示感谢。并表示今后将率更多的荷兰企业到大连实地考察，举办高规格的企业对接洽谈，寻求广泛深层次的合作。

At the end of each day the recording devices are plugged into special docking stations and the recordings are uploaded to Recordant's headquarters for analysis.

在每一天的结束，录音装置会被接入到一些特别的资料汇集站，然后录音记录会被上传到Recordant公司的总部进行分析。

At the end of each day the recording devices are plugged into special docking stations and the recordings are uploaded to Recordant's headquarters for analysis.

尽管很多人对于隐私提出质疑， Recondant 公司负责人表示：与打电话直接进行调查相比，这种间接调查一定是更为广为接受的。

Poor fuel economy, a snugger third row, and slower acceleration prevent the Armada from docking on top.

高油耗，较舒适的第三排座椅，较慢的加速使得Armada无法第一

Using the crystal structure of CDK2 complexed with indirubin-5- sulphonate as the template, models of CDK4 complexed with indirubin and its analogue were built by homology modeling and molecular docking.

以获得晶体结构的CDK2与5-磺酸根-靛玉红的复合物为模板，通过同源模建和分子对接的方法构建出的CDK4与靛玉红及其衍生物的结合模式。

If Titan II inserted C taur into orbit, it would have enough power after docking to boost the spacecraft to escape velocity.

如果提坦Ⅱ将森托尔送人轨道，对接后森托尔还会有足够的能量推进飞船摆脱速度限制。

Our service includes: liner agents, tramper and tanker agents, protective agents, bunkering, provision and ship's store supply, ship surveying and repairing, crew changes and repatriation, marine consulting, handling cargo claims and marine casualties, chartering,cargo forwarding, ocean freight collection, transshipment and haulage, terminal operation, warehousing, hull cleaning, dry docking, cargo insurance and inspections, container depot and management.

服务范围包括：班轮代理；不定期船和油轮代理；保护代理；船舶燃料、物料供应；船舶检验和维修；更换和遣返船员；承揽货物及其订舱、仓储、转运和多式联运；代为结算运费、代收代付款项；洽办租船、理赔、海商、海事处理；船体清洁、干坞；集装箱堆场和管理等。

Repeat over the undocked screen and select docking.

重复对停靠屏幕和选择对接。

While the aft docking station makes the enclosed bridge version a viable contender for fishing honors, the 60 EB will appeal to cruising yachtsmen because it offers all of the ruggedness, performance, speed and handling of its sistership with the style, accommodations and luxury of a true motor yacht.

而尾部对接站，使封闭的桥梁版本一个可行的竞争者捕鱼的荣誉， 60个电子束将呼吁巡航游艇驾驶员，爱好，因为它提供了所有的耐用性，性能，速度和处理其sistership与作风，住宿和豪华的一真正的汽车游艇。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。