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Among those hydrogenbonding residues, Tyr119, His227, Asn392 and Leu451 could form hydrogen bond with the benzofuran inhibitots and Tyrl07, Asn175, Thr211 and Asp412 were newly discovered hydrogen-bonding residues, which were highly conserved residues across the NMT family and would play an important role in the design of NMT inhibitots with novel chemical scaffold.

CaNMT活性位点发现有两个氧键作用区域，其中Tyrll9，His227，Asn392和Leu451是与已有抑制剂的氢键结合位点，Tyr107，Asn175，Thr211和Asp412是新发现的氢键结合位点，而且在NMT家族中高度稳定，它们对设计新结构类型的CaNMT抑制剂具有重要作用。

It is first discovered that guazatine can react with benzoin and its derivative has strong fluorescence.

首次发现双胍辛胺与安息香可发生反应，产物具极强的萤光活性。

Plutonium was first discovered in a Berkeley lab (as were the aptly-named berkelium and californium).

放射性元素钚就是首先在巴克利实验室发现的（确切的名字该叫巴克利姆或加利福利姆）。

In Paris, he frequented artistic circles which brought him into contact with a number of artists, including Sarah Bernhardt, and he discovered a strong affinity for the work of Vincent van Gogh.

在巴黎，他经常光顾艺术界使他接触到大量的艺术家的作品，包括萨拉·伯恩哈特下，他发现有很强的亲和力的文森特·高。

One day, she went to the forest to pick some berries, and she discovered a new berry.

有一天 ，她到森林里去采果子。偶然间，她发现另一种果子。

Little by little, reading in Edward's mind, Bertha discovered to her delight an unexpected purity .

逐渐地，由于对爱德华内心的观察，伯莎高兴的发现了一种意外的纯洁。

The paradox discovered by Bertrand Russell in the early twentieth century, however, led to a major reconsideration of its founding principles.

悖论发现罗素在20世纪初，但是，导致了重大的重新审议其创始原则。

Beverley was ecstatic when she discovered a box containing a hand crafted, one of a kind gold bracelet that she'd been admiring for quite some time.

两项比赛的快感，当她发现一个盒子，里面装着一个订单精工，一类中的一个金手镯，她早晨一直向往多时。

Years later, John Bevis swept up its dim remnant and put it in his"Uranographia Britannica". Bevis discovered the Crab 27 years before Messier did.

贝维斯终於找到了这颗超新星暗淡的遗骸，并把它编入他绘制的《不列颠星图》内，这就是天文观测者所熟知的M1，贝维斯的发现比梅西尔早了足足27年。

But by the age of 7, Bianca discovered that she really enjoyed singing.

到了7岁的时候，比安卡发现她真的对音乐产生浓厚的兴趣。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。