查询词典 discontinuation

In nonsmokers without pulmonary disease at baseline, there were no severe decreases in lung function attributed to Exubera, and high-resolution chest computed tomography revealed no evidence of notable lung changes. Completed phase 2 and 3 studies that followed patients for up to 4 years indicate that the differences over time in pulmonary function changes between patients treated with Exubera and control patients are small, nonprogressive, clinically insignificant, and reverse after discontinuation of Exubera therapy.

Feb。 9， 2006 --尽管一开始对於肺功能影响的顾虑，美国食品药物管理局仍然批准辉瑞药厂生产的吸入性胰岛素Exubera使用於成人第1、2型糖尿病；该核准案於1月27日通过，也就是欧盟核准该药物上市后隔天；自从胰岛素於1920年代被发现以来，吸入型粉状的基因重组人类胰岛素是第一个新的胰岛素投与选择；临床试验数据显示，使用exubera一开始会使肺功能下降，但是并非进行性的，其效果与一般胰岛素相当，而且具有病患顺从性较高的优点。

Methods The present study is a randomized comparative clinical trial. 607 healthy parous women were randomly allocated into GyneFix IN group (n=302) or TCu 380A group (n=305). IUD was inserted during the menstrual interval by the trained investigators. Follow-up were arranged at 1,3,6 and 12 months after insertion. The discontinuation rates were calculated by life table method.

采用随机对比性多中心临床研究方法，对607例健康经产妇女由经过培训的专人以随机方法于月经间期放置GyneFix IN IUD 320例(GyneFix IN组)及TCu 380A IUD 305例(TCu 380A组)，于放器后1、3、6和12个月随访，以生命表法统计两种IUD的终止情况。

Healthy parous women were randomly allocated into GyneFix IN group (n=302) or TCu 380A group (n=305). IUD was inserted during the menstrual interval by the trained investigators. Follow-up were arranged at 1,3,6 and 12 months after insertion. The discontinuation rates were calculated by life table method. Results At the end of the first year, there was no pregnancy occurred in GyneFix IN group.

采用随机对比性多中心临床研究方法，对607例健康经产妇女由经过培训的专人以随机方法于月经间期放置GyneFix IN IUD 320例(GyneFix IN组)及TCu 380A IUD 305例(TCu 380A组)，于放器后1、3、6和12个月随访，以生命表法统计两种IUD的终止情况。

Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前，Mahon医师等人主导一个先驱研究，探索完整分子生物学上缓解之CML病患停用imatinib的可能性，在总共15名病患中，7人在6个月内復发，但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解，其他8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前，Mahon医师等人主导一个先驱研究，探索完整分子生物学上缓解之CML病患停用imatinib的可能性，在总共15名病患中，7人在6个月内复发，但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解，其他8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

Previously, Dr. Mahon and colleagues conducted a pilot study and explored the feasibility of discontinuing imatinib in CML patients who had experienced a complete molecular response. Of the 15 patients included in the cohort, 7 relapsed within 6 months, but they were able to reattain a complete molecular response after imatinib was restarted. The other 8 patients remain in remission after the discontinuation of imatinib (median follow-up is 37 months).

之前，Mahon医师等人主导一个先驱研究，探索完整分子生物学上缓解之CML病患停用imatinib的可能性，在总共15名病患中，7人在6个月内复发，但他们可以在再度使用imatinib之后再度达到完整分子生物学上缓解，其它8个病患在停用imatinib之后持续缓解(平均追踪期为37个月)。

They found that 27 (73%) patients had iron-deficiency anemia, as confirmed by bone marrow aspiration, while two (5.4%) patients had dilutional anemia, as indicated by normal red blood cell olumes on chromium radioisotope-labeled erythrocyte analysis, and one (2.7%) had enalapril-induced anemia that resoled upon treatment discontinuation and returned upon treatment rechallenge.

他们发现27个(73%)患者经骨髓穿刺诊断患有缺铁性贫血，2个(5.4%)患者经铬标记红血球分析红细胞法诊断稀释性贫血，1个(2.7%)因中途停药后又重新治疗的患者患了依那普利引起的贫血。

Data from the national key research "A multicentre study of 2 types of domestic levonorgestrel subdermal implants" were analyzed to study the factors that may be associated with discontinuation of two types of levonorgestrel subdermal implants due to menstrual irregularities among Chinese users.

国内外有关皮下埋植剂的应用研究表明：它的有效性非常高，在使用的前两年几乎可以与输卵管结扎相媲美，但其可接受性在很大程度上受到了单纯孕激素引起的副反应的影响。

During the year, the various forms of enforcement actions taken resulted in the discontinuation of 208 UDs covering 59 hectares of land.

年内，当局采取各种强制执行行动后，208宗涉及59公顷土地的违例发展已停止进行。

Begin with metformin unless evidence or risk of renal impairment, titrating the dose over early weeks to minimize discontinuation due to gastro-intestinal intolerance.

如果没有肾脏受损或有受损危险的情况下，起始应用二甲双胍治疗。在最初的几周调整剂量，将由于胃肠道不适引起的停药减小到最少。

Hanna: That's over now, isn't it?

都结束了，对吗

You must be ill. You look so pale.

你一定是病了，你的脸色苍白。