查询词典 dihydro-compound

TPS produces and sells pharmaceutical intermediates made from local resources, including L-dopa,Artemisinin ,artesunate, dihydro artemisinin, shikimic acid, mangiferin, camptothecin, star anise oil,ursolic acid , rosmarinic acid, anethole,etc.

产品有：左旋多巴，青蒿素，青蒿琥酯，双氢青蒿素，蒿甲醚，莽草酸，八角茴香油，芒果甙，喜树碱，熊果酸等当地资源生产加工的天然植物提取物。

In the first step of thedouble annulation route, 2-amino-3-carbamoyl-5,6-dihydro-4-pyridones 2 werecreated in high to excellent yields by a formal [5C + 1N] annulation reaction ofketene--acetals 1 with ammonia.

第一步，二硫缩烯酮1和氨源通过[5C + 1N]加成反应产率极高的得到了2-氨基-3-氨基甲酰基-5，6-二氢-4-吡啶酮2。

IV. The total synthesis of dehydrodiconiferyl alcohol and its dihydro-derivative The benzofuran skeleton was constructed by chemically oxidative couplingstarting from vanillin, then selective reduction with LiAI〓/〓 andhydrogenation in the presence of Pd-C followed reduction with LiAl〓respectively, to give dehydrodiconideryl alcohol and its dihydro-derivative, usefulin treating and preventing digestive system disorders, esp.

四、Dehydrodiconiferyl alcohol及其二氢衍生物的全合成以香草醛为起始原料，用化学氧化法一步建立氢化苯骈呋喃骨架，LiAlH〓／〓选择性还原以及催化加氢还原接着〓还原，分别合成了对预防和治疗消化系统疾病尤其是胃溃疡有显著效果的Dehydrodiconiferylalcohol及其二氢衍生物。

Two kinds of haptens 6-{[(2,3-Dihydro-2,2-Dimethyl-7-benzofuranyloxy)carbonyl] -amino}hexanoicAcidand4-{[(2,3-Dihydro-2,2-Dimethyl-7-benzofuranyloxy) carbonyl]-amino}butanoic Acid has been synthesized by chemical way.

本研究以2，3-二氢-2，2-二甲基-7-苯并呋喃氯甲酸酯为基础合成了克百威的两种半抗原，6—

They are 4-(2- hydroxy-3-butynlenoxy) benzoic acid (1, WA), 5-chloro-7, 8-dihydroxy-7-methyl- 6-oxo-3- [ -3, 4-dihydroxy-3, 5-dimethyl-l-heptylene] -1H-8, 8a-dihydrobenzo [2, 3-c] pyran (2, WB),-2-(2-methyl-2-dibutene diamido)-2-butenoic acid (3, B5262), 3, 4-dihydro-9, 10-dihydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3- c] pyran-1-one (4, A73 semi-Vioxanthin), 8, 8'-bis (6, 9-dioxo-3,4-dihydro-10- hydroxy-7-methoxy-3-methyl-1H-naphtho [2, 3-c] pyran-1-one)(5, A122 Xanthomegnin), 2, 5-dioxo-3a-hydroxymethyl-3, 3a, 6, 6a-tetrahydro-furo [2, 3-b] furan (6, 1003-2), 7-acety1-5-chloro-6, 8-dioxo-7-methyl-3- [ -3, 5-dimethyl-1, 3- diheptylene] -4aH-benzo [2, 3-c] pyran (7, M2-2 sclerotiorin), respectively.

它们分别被命名为4-（2-羟基-3-丁炔氧基）苯甲酸（1，WA）、5-氯-7，8-二羟基-7-甲基-6-氧代-3-[-3，4-二羟基-3，5-二甲基-1-庚烯基]-1H-8，8a-二氢苯并[2，3-c]吡喃（2，WB）、-2-（2-甲基-2-丁烯二酰亚胺基）-2-丁烯酸（3，B5262）、3，4-氢-9，10-二羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮（semi-Vioxanthin，4，A73）、8，8'-双（6，9-二氧代-3，4-二氢-10-羟基-7-甲氧基-3-甲基-1H-萘并［2，3-c］吡喃-1-酮）（Xanthomegnin，5，A122）、2，5-二氧代-3a-羟甲基-3，3a，6，6a-四氢-呋喃并［2，3-b］呋喃（6，1003-2），7-乙酰基-5-氯-6，8-二氧代-7-甲基-3-［-3，5-二甲基-1，3-庚二烯基］-4aH-苯并2，3-c］吡喃（Sclerotiorin，7，M2-2）。

The active ingredient of α-pyrone 0.2% wettable powder is 5,6-dihydro-6-pentyl-2H-pyran-2-one.

0.2%α-吡喃酮WP的有效成分为5，6-二氢-6-戊基-2H-吡喃-2-酮(5，6-dihydro-6-pentyl-2H-pyran-2-one)。

In part one, the reactions of some active fluorine-containing compounds such as 2, 2-dihydropolyfluoroalkanoic acids and ethyl 2-hydropolyfluoroalkenoates were studied and various fluorine-containing heterocyclic compounds were synthesized. Using 2, 2-dihydropolyfluoroalkanoic acids as the starting material, 4-fluoroalkyl quinolin-2-ols, 2- [ -1-hydropolyfluoro-1-alkenyl] -4H-3, 1-benzoxazin-4-ones, 1-aryl -4, 9-dihydro-3-fluoro-alkyl-1H-pyrazo [3, 4-b] quinolin-4-ones, 5-fluoroalkyl-12H-quin olino [2, 1-b] quinazolin-12-ones, 4-fluoroalkyl-1, 3-dihydro-1, 5-benzodiazepin-2-ones and 4-fluoroalkyl-2H-pyrido [1, 2-a] pyrimidin-2-ones were synthesized through its condensation reaction with anilines, anthranilic acid, N'-aryl-o-aminobenzamides, o-nitro aniline, o-amino pyridine and their derivatives and the subsequent transformations. 5-Fluoroalkyl isoxazolidines, 3-fluoro-3-fluoroalkylisoxazolidino [4, 3-c] quinolin-4-ones, 3-fluoroalkylisoxazolino [4, 3-c] quinolin-4-ones and 2-aryl-3per fluoroacylindoles were synthesized by inter-and intramolecular 1, 3-dipolar cycloaddition of fluorine-containing olefins and nitrones.

第二部分，我们研究了α，α-二氟苄基卤类化合物的亚磺化脱卤反应、产物的转化及全氟烷基亚磺酸盐与芳环化合物的全氟烷基化反应，发现全氟苄基碘或溴及α，α一二氟苄基溴在保险粉等亚磺化脱卤试剂引发下可生成相应的亚磺酸盐；全氟苄基亚磺酸盐与氯气或溴反应可生成全氟苄基磺酰氯或磺酰溴；在烯烃存在下，全氟苄基碘则与烯烃发生加成反应，生成相应的1：1加成产物；在三价醋酸锰的作用下，部分芳香化合物如茴香醚，二甲氧基苯，吡啶，喹啉等可以和过量的全氟烷基亚磺酸盐发生双全氟烷基化反应，反应表现出一定的区域选择性，产率良好。

Synthesis process Molecular Formula:〓 Molecular Weight: 394 Chemicla name: N-(2, 3-dihydro-2, 7-dimethyl-benzofuran-1-acyl)-N'-tert-butylN'-(3, 5-dimethyl benzoyl) hydrazine Structural formula:〓 This article define a synthesis method of JS118 with (2, 3-dihydro-2, 7-dimethylbenzofuranyl)-6-formic acid, tert-butyl hydrazine hydrochloride acid and 3, 5-dimethyl benzoic acid as main intermediate through four steps of reaction involving, acyl chloridation condensation and so on.

本文主要的研究工作内容：(1)以N-特丁基双酰肼为先导结构，利用分子等排原理和类同合成法进行先导设计，有目的、有选择地重点改变R〓、R〓基团，将具有不同取代基的苯环以及呋喃环、苯并呋喃环、吡咯环、吡啶环等杂环、稠杂环与先导结构进行有机的组合。

Three aspects were included here:The derivatives of dihydrol,2,4,5-tetrazine-3,5-dicarboxylic acid were synthesized via three different routes:(1) four new compounds were synthesized via the reaction bet ween dihydrol,2,4,5-tetrazine-3,5-dicarboxylic acid, thionyl chloride and corresponding alcohol ;(2) first ,dimethyl dihydro-1,2,4,5-tetrazine-3,5-dicarboxylate wer e synthesized, then ,another four new compounds were obtained t hrough the alcoholysis under the catalyst ;(3) three acylamines were got through the ammonolysis betw een dimethyl dihydro-1,2,4,5-tetrazine-3,5-dicarboxylate and amines.

本论文分别通过三条不同的路线合成了1，4-二氢-3，6-二甲酸-s-四嗪的衍生物：(1)通过1，4-二氢-3，6-二甲酸-s-四嗪与氯化亚砜和相应的醇反应，制备了四个新化合物；(2)合成1，4-二氢-3，6-二甲酸甲酯-s-四嗪，在催化剂的作用下，与高沸点的醇进行酯交换反应，合成了四个新化合物；(3)合成1，4-二氢-3，6-二甲酸甲酯-s-四嗪后，与胺进行氨解反应，合成三个新的1，4-二氢-3，6-二甲酰胺-s-四嗪化合物。

Investigation of major metabolic pathways of SFZ-47 in animals The metabolites of SFZ-47 in rabbit urine following oral administration were separated and detected with HPLC and LC-MS methods. On the basis of the chromatographic behavior and mass spectra of the metabolites as well as biotransformation pathways of drugs with the partial structure of SFZ-47, the hydroxylic derivative 4-(3H-1, 2- dihydro-1-pyrrolizinone-2-methylamino benzyl alcohol and the carboxylic derivative 4-(3H-1, 2-dihydro-1-pyrrolizinone-2-methylamino benzoic acid of SFZ-47 were proposed as two potential metabolites and were synthesized.

在动物体内主要代谢途径的确定用HPLC和LC-MS对家兔口服SFZ-47后尿中的代谢物进行了分离、检测，根据代谢产物的色谱和质谱行为以及与SFZ-47有类似结构部分的其它药物的代谢途径，推测其羟基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲醇]与羧基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲酸]是两种可能的代谢产物，遂用化学方法合成了这两种衍生物。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。