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The expression level of metabolitic enzyme (CYP1A1, CYP1B1) and its correlation with cell differentiation /apoptosis were studied as well. The influence of resveratrol in cell cycle was determined with FCM. Results 1 Resveratrol not only suppresses the growth of medulloblastoma cells in a dose and time related fashion but also induces cell differentiation and apoptosis. Resveratrol promotes differention of UW228-1,-2 cells to forward glia, UW228-3 and Med-3 cells to neuron. A treatment of resveratrol in the concentration of 100μM for 48hrs comit most of cells die of apoptosis. 2 Among the four cell lines Fas and Caspase-3 were constantly expessed, whereas FasL was absent irrespective to the drug treatment. 3 ICC, RT-PCR, Western-blot hybridization and EROD enzymatic activity assay demonstrated that expression of CYP1A1 is different after treatment with resveratrol in four cell lines, up-regulated in three UW228 cell lines in a dose dependent manner but down-regulated in Med-3 cells. Suppressive effect of resveratrol on CYP1B1 expression is the same among four medulloblatoma cell lines. 4 Cell cycle distribution of UW228-3 was greatly changed after treatment.

结果：1、白藜芦醇以时间和剂量依赖性方式抑制髓母细胞瘤细胞生长，同时促进细胞的分化和凋亡：白藜芦醇促使UW228-1、-2靶细胞向神经胶质细胞方向成熟分化，UW228-3、Med-3细胞向神经元细胞方向成熟分化，以100μM作用48小时效果显著；2、四个细胞系均有Fas和Caspase-3表达，但无Fas-L基因表达和蛋白活性产生，因此难以形成Fas相关性死亡通路；3、白藜芦醇处理前后CYP1A1基因的表达在各细胞系略有不同：UW228-1，-2，-3三个细胞系白藜芦醇以剂量相关性方式上调CYP1A1的表达，而Med-3细胞系，白藜芦醇却抑制CYP1A1的表达；四个细胞系在白藜芦醇处理后CYP1B1的表达均受到抑制；4、UW228-3细胞系经白藜芦醇作用后细胞周期有较大改变，表现在G0/G1期在整个细胞周期中所占的比例增加，而其它时期则相应减少。

Most of them are either cruelly killed by other animals or slowly die of hunger.

它们中的大多数，或者被其它动物残酷地杀害，或者慢慢地饿死。

To 20% of people with diabetes die of renal failure.

10%到20%的病人死于肾功能衰竭。

But after she was crying row, we as a bulk of money off disaster, she wanted the number of how many yew her later as she said,"make a clean break, die of old age are not in contact with."

但经过她大哭大闹下，我们当作是散钱破灾，她要多少就给了她多少，以后正如她所说的"一刀两断，老死不相往来。"

Its reputation in India is that of a place where people still die of hunger.

在印度，这片地方由于人们仍然因饥饿死亡而闻名。

Nobody ever dies of AIDS or HIV, they die of a common illness because their body is too weak to fight anymore

没有人直接死于AIDS或HIV，艾滋病人经常死于一些常见的小病。因为他们的身体非常虚弱，无法抵抗任何侵袭

Statistics indicate that more than 12 million Americans have died from smoking since the 1964 report of the surgeon general, and another 25 million Americans alive today will most likely die of a smoking-related illness.

统计显示，超过12万美国人死于吸烟自1964年报告的一般外科、另有25万美国人死于健在很可能与吸烟有关的疾病。

Before the term was over I had left for Tokyo, because after this film I felt that medical science was not so important after all. The people of a weak and backward country, however strong and healthy they may be, can only serve to be made examples of, or to witness such futile spectacles; and it doesn't really matter how many of them die of illness.

这一学年没有完毕，我已经到了东京了，因为从那一回以后，我便觉得医学并非一件紧要事，凡是愚弱的国民，即使体格如何健全，如何茁壮，也只能做毫无意义的示众的材料和看客，病死多少是不必以为不幸的。

Who expects, just hanged a phone,"Old fishing old man " the information that receives father to die of illness, his the same night hurrieds back native place hastens home for the funeral of a parent or grandparent.

谁料，刚挂了电话，"老渔翁"就接到父亲病故的消息，他连夜赶回老家奔丧。

Everyday, I will drink a lot of water, or else I would be die of thirst.

我可以逃脱晚自习，然后可以睡个好觉，当一停电的时候我都会兴奋不已。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。