查询词典 deamidation

Protein deamidation is one of the post-translational modifications which also include phosphorylation, methylation and acetylation.

蛋白质的去胺基化是属於后转译的修饰作用，其中还包括磷酸化、甲基化及乙醯化。

The changes of intermolecular forces and secondary structure of the rice protein modified by deamidation with acid were studied.

大米蛋白经酸法脱酰胺改性引起分子间作用力和二级结构发生变化。

Whether cisplatin induced Bcl-xL deamidation may be inhibited by NAC, remains to be determined.

是否cisplatin引发的Bcl-xL 去胺基化，可能受到NAC抑制，仍待进一步证实。

Deamidation has been proposed to serve as a molecular timer, regulating variant cellular responses, including protein turnover, development and cellular aging.

去胺基化被认为是调控细胞反应的分子时钟，包括蛋白质转换率，细胞发育和细胞老化等。

Deamidation of asparaginyl and glutaminyl residues have been proposed to serve as a molecular clock regulating biological events such as protein turnover, development, and cellular aging.

天冬醯胺和谷氨醯胺这两个氨基酸的去胺基化被认为是调控细胞反应的分子时钟，这些反应包括蛋白质的转换率，细胞发育和细胞老化等。

The stability experiments of GEON were achieved at two temperatures, 30℃(180 days) and 85℃(6 weeks). The rate of deamidation were 6. 0% and 8. 53% respectively, lower than 10%, so the product was valid for two years.

活性肽产品的贮藏稳定性试验表明，30℃留样观察180天，酰胺水解率6.0％，85℃加速实验6周，酰胺水解率8.53％0％，因而该产品的有效期通常可达两年。

RESULTS: The Bcl-x deamidation pathway was inhibited in myeloid cells, but not T cells, in patients with CML or polycythemia vera.

结果：CML患者或真性红细胞增多症患者的Bcl -×脱酰胺途径受抑制是在髓系细胞中，而不是T细胞。

Recent studies showed that deamidation of Bcl-xL, an anti-apoptotic protein, regulates cellular response to DNA damage. This Bcl-xL deamidation induced by cisplatin appears to be mediated by p53 and Rb.

目前有研究显示在DNA损伤下，抗死蛋白Bcl-xL的去胺基化可调控细胞反应，而在抑癌基因p53和Rb 突变的癌细胞中也发现抗癌药物cisplatin的处理会导致Bcl-xL 的去胺基化。

From in vitro alkaline pH assay and site-directed mutagenesis of Bcl-xL at two potential deamidation sites, where Asn 52 and 66 were replaced by Ala or Asp residues, we concluded that this Bcl-xL modification was due to deamidation.

此外，外送去胺基化Bcl-xL的表现，也会使SKOV3-ip1细胞对cisplatin较为敏感；而其效果是与E1A增加cisplatin之敏感性相等。

Enzymes could enhance the deamidation rate of Gln residues. Nutrase was the most effective. The rate of deamidation by Nutrase after 6 hours at the given conditions were up to 40.85 percent, followed by alkaline enzyme and papain. Prozyme A, flavourzyme, pepsin had no obvious effect.

蛋白酶具有明显的水解酰胺基的作用，以中性蛋白酶为最，反应6小时，脱酰胺率高达40.85％，碱性蛋白酶和木瓜酶次之，复合酶A、风味酶和胃蛋白酶的作用较小。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。