查询词典 de novo

If an affected child is born to clinically unaffected parents, it is likely that the child has a de novo mutation, and the risk to sibs is far less than 50% but above the population risk because of reported cases of somatic and germline mosaicism.

如果临床无症状的父母但下患病儿童，很可能这个儿童发生了新生突变，而患儿的兄弟姐妹患病的风险远比50％小得多，但比普通人群风险高因为曾报道过体细胞和生殖细胞嵌合体的案例。

De novo pyrimidine biosynthesis, which is also referred to as the "orotate pathway", is one of the most important methoblism pathways in plants.

因此，嘧啶核苷酸的代谢及其在细胞间的储备量直接影响着整个细胞的正常代谢和生物体的生长发育。

Specific applications include de novo sequencing and re-sequencing of genomes, metagenomics, RNA analysis, and targeted sequencing of DNA regions of interest. The hallmarks of 454 Sequencing? are its simple, unbiased sample preparation and long, highly accurate sequence reads, including paired reads.

具体的应用包括基因组的从头测序和重测序、宏基因组学、RNA分析和DNA目标区域的定向测序。454测序系统的特点是样品制备简单且无偏向性，读长超长且准确度高。454测序系统的技术已经催生了各个研究领域的几百项经同行评议的研究文章，例如癌症和传染病研究、药物筛选、海洋生物学、人类学、古生物学等各方面研究。

Serum levels of Ang-2 and VEGF in 24 de novo, 18 complete remitted, 7 unremitted, 13 relapsed patients with AL were measured by enzyme-linked immunosorbent assay, and compared with those of normal controls.

应用酶联免疫吸附试验测定24例AL初发未治，18例完全缓解，7例未缓解，13例复发患者血清中Ang-2和VEGF的含量，并与正常对照组比较。

Exposure to these compounds activates virA, which acts on virG, which in turn induces the expression de novo of virB,C,D,E.

暴露于这些化合物中时，virA被激活，它作用于virG，virG又依次诱导virB.C.D.E的表达。

Although the biological significance of DNA methylation has been recognized to some extent, the mechanisms of DNA methylation regulation and of the establishment of tissue-specific DNA methylation pattern in somatic cells are still unclear, since the knowledge of the enzymes responsible for de novo DNA methylation and demethylation of DNA is very limited and up to now only two functional DNA methyltransferases in mammals have been cloned.

目前，虽然对DNA甲基化的作用已有一定认识，但DNA甲基化的调节以及发育过程中组织特异的DNA甲基化谱的建立机制还不清楚。问题主要在于对催化重新甲基化和去甲基化反应的酶的了解很少。至今仅克隆出两种有功能的哺乳动物DNA甲基转移酶。

The Jewish apocalypses furnish the completing links in the progress of Jewish theology and fill what would otherwise be a gap, though a small one, between the advanced stage marked by the deuterocanonical books and its full maturity in the time of Our Lord; a maturity so relatively perfect that Jesus could suppose as existing in the popular consciousness, without teaching de novo , the doctrines of future retribution, the resurrection of the body, and the existence, nature, and office of angels.

犹太人提供启示完成环节的进展情况犹太神学和填补否则差距，虽然很小，晚期之间的显著的书籍和deuterocanonical充分成熟的时候我们的上帝；成熟，以便比较完善的，耶稣可以假设现有的全民意识，没有教学从头，理论未来报复，复活的身体，存在，性质，和办公室的天使。

Approximately 1% of mutations occur de novo ; thus, 1% of probands have only one parent who is heterozygous.

约1%的突变是新生突变；因此，1%的先证者只有一个杂合子的父母。

We believe that these lesions overlap histomorphologically with higher-grade dysplastic nevi and de novo intraepidermal epithelioid melanocytic dysplasia.

我们认为，这些病变与分级较高的发育异常痣和新生表皮内上皮样黑色素细胞发育不良存在着组织形态学的重叠。

This process, called vasculogenesis ,involves the de novo differentiation of endothelial cell from mesodermal precursor to form the primitive blood vessel network.

血管生成是指在胚胎发生和器官形成过程中，从中胚层内皮细胞中分化出新的内皮细胞以形成原始血管网的过程，仅见于胚胎发生的早期，出生后即停止。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。