查询词典 damnify

The former stimulates the cells and transfer the signals into the cells through the ligation with receptors on the cell membrane. The latter, a derivative of nucleotide, causes a cytotoxic effect to suppress thymidylate synthetase activity, and, therefore, to damnify RNA and DNA synthesis.

前者通过与细胞表面的受体结合，把胞外刺激传递到胞内，诱导免疫受体介导的信号级联放大作用，引起一系列免疫效应；后者是是小分子的核苷酸衍生物，可直接进入细胞内，通过抑制胸苷酸合成酶及损伤RNA、DNA等对基因转录和核苷酸代谢产生影响，最后产生细胞毒效应。

The mutagen mechanism is presumed single factor dominant.(4)There was 85 percent transvertion in mutagen spectra, and they were all G:C→T:A transvertion. The maximal possibility of mutagen mechanism is analyzed as followed:ion beam implant → breakage cell surface and enter the interior → stimulate plentiful radical born → radical oxidize and damnify DNA → G becomes 8—oxoG → 8—oxoG pairing A → result in G:C→T:A transvertion(5)Production of transition was presumed that ion beam implantion damnified DNA, stimulate activity of MMR interveniented by methyl reducing.

诱发突变谱中碱基颠换比例是0.85，且是全部G：C→T：A颠换，推测低能离子束诱变鼠伤寒沙门氏菌得分子机制可能为：离子注入→通过破坏细胞表面进入内部→刺激产生大量自由基→自由基氧化损伤DNA→G变成8氧—7，8—二氢鸟嘌呤(8—oxoG)→8—oxoG与A配对→导致G：C→T：A颠换。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。