查询词典 cytotrophoblast

On the morphological differentiation,by inducing of fetal calf serum,it wasshown that the cytotrophoblast cells underwent aggregation first,and the adjacentcytoplasm membranes became tightly contacted through desomosomes andcytoskeleton.Then the adjacent cytoplasm membranes disintegrated fragmentallyto form fusion pore-like structure.Finally the multinuclear cells formed and inwhich the intercellular desmosomes disappeared.Immunocytochemical stainingfurther demonstrated that the formation of syncytium was through cell membranefusion rather than the amitosis process.

细胞形态分化的研究结果表明：早孕胎盘来源的细胞滋养层细胞在血清诱导下，首先发生聚集，并通过桥粒和细胞骨架使相邻的细胞膜紧密接触；之后细胞膜发生片段断裂，形成融合孔样结构；细胞间桥粒消失，最终形成多核的合体细胞；免疫细胞化学分析进一步证实合体化是通过细胞膜融合而非无丝分裂（amitosis即细胞核分裂而细胞质不分裂）实现的。

On the functional differentiation,we found and that the type II ras-GTPaseactivating protein (p100-GAP),which was specifically expressed in humanplacenta,was largely expressed in the highly-differentiated syncytiotrophoblastcells and moderately expressed in the cultured intermediate trophoblast cells.While in the non-differentiated cytotrophoblast cell line-NPC,no expression was observed.Its mRNA and protein expressingcharacterization was in consistent with that of hCGβ,which was one of the mostimportant markers of the trophoblast cell functional differentiation.In addition,the expressing amount of p100-GAP increased with the progressing of pregnancyand the syncytium formation in vitro.

细胞功能分化的研究结果表明：经重组质粒的构建获得特异表达于人胎盘的p100－GAP的cDNA探针后，从蛋白和分子水平证实p100－GAP大量表达于分化程度高的合体滋养层细胞，少量表达于体外培养的中间型滋养层细胞，而非分化的细胞滋养层细胞NPC则不表达，这种表达特性与作为滋养层细胞功能分化重要指标之一的hCGβ高度一致；p100-GAP表达量还随妊娠过程和体外合体化过程而逐渐增加。

Positive immunostain Fas and FasL was mainly located in the cytoplasm and membrane of syncy-tiotrophoblast and cytotrophoblast.

Fas及FasL在重度子痫前期组胎盘绒毛滋养细胞的表达与新生儿出生体重和胎盘重量均有明显相关性。

Results:Among 20 placenta tissues of the test group,16 samples were found to have Uu infection to different degrees,which resulted in pathological changes of villous cytotrophoblast and villous middle.

结果：试验组胎盘组织中有16例发现有不同程度的Uu感染现象，并引起绒毛滋养层细胞和绒毛间质发生不同程度的病理改变。

In order to avoid the shortcomings of cytotrophoblasts from early first trimester or term villous cytotrophoblast, the differentiated RS366. 4 was used as new early cytotrophoblast model.

为避免由早期胚胎标本或胎盘来源的细胞滋养层细胞模型的不足，本实验选用由猕猴RS366.4 ES细胞来源的早期分化滋养层细胞为模型进行研究。

As we know that human placentalsyncytiotrophoblast cell derlves from the fused cytotrophoblast cell and fetal calfserum can be able to induce the term placental cytotrophoblast cell fusion in vitro.

妊娠过程中，合体滋养层细胞分泌的hCG可促进卵巢黄体和胎盘分泌孕酮，在维持妊娠中起着重要的作用；然而未分化的细胞滋养层细胞不能合成hCGβ。

Uu not only bring out corresponding ultrapathological changes by adhering to the surface of the cytotrophoblast membrane,but also enters the body of the cytotrophoblast and does harm to them directly.

Uu不仅吸附在滋养层细胞膜表面诱发相应的超微病理改变，而且还进入滋养层细胞体内，对滋养层细胞产生直接杀伤作用。

Results The expression of ADAM19 are mainly in the cell membrane, plasma and column of cytotrophoblast; The expression of ADAM19 is mainly located on cytotrophoblast during first trimester of pregnancy, and on syncytiotrophoblast in second and third trimester.

结果ADAM19的表达主要集中在滋养细胞的细胞膜、细胞质中和细胞滋养层柱细胞中；早孕绒毛中，ADAM19表达主要集中于细胞滋养细胞膜，在晚孕期胎盘，ADAM19主要表达于合体滋养细胞膜。

Results:(1)The expression place: LOX-1 and Caspase-3 are expressed in syneytiotrophoblast, cytotrophoblast of villus in early pregnancy, and they are expressed in syneytiotrophoblast, cytotrophoblast and vascular endothelial cell of placenta of normal in middle and advanced stage.

氧化损伤能够诱导胎盘细胞凋亡[4]，在正常妊娠过程中，体内氧化和抗氧化损伤相互制约，进而达到平衡状态，如果该平衡被打破，则发生流产，早产，妊娠高血压综合症等病理妊娠。

From the early study of the pathogenesis of pre-eclampsia people have found its association with immunological function . In 1986 Ellis et al[1] had found that the extravillous chorionic cytotrophoblast contacting with the maternal tissue expressed high levels of Human leukocyte antigen-G, a major histocompatibility tissue-specific antigen . Extravillous chorionic cytotrophoblast with high levels expression of HLA-G proteins can invade the maternal deciduas and the maternal spiral arteries by displacing the endothelial lining and destroying most of the musculoelastic tissue of these arteries .

早期研究开始，许多学者即发现其与免疫学有密切关系，至1986年Ellis等[1]发现人类白细胞抗原(human leukocyte antigen，HLA) G分子高度表达在绒毛外滋养层细胞( extravillous cytotrophoblast，EVCT)上，即浸润至子宫蜕膜层甚至达子宫浅肌层以及子宫螺旋动脉内皮层，与母血及子宫组织直接接触的滋养细胞，这种独特的组织分布提示HLA-G分子在母胎免疫耐受方面起重要作用。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐