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Objective To study the effect of laminin on invasive and metastastic behaviors of salivary adenoid cystic carcinoma cell lines.

目的 研究层粘连蛋白与人涎腺腺样囊性癌(adenoid cystic carcinoma,Acc)转移的关系。

ABSTRACT Objective To discuss the importance of the study of conformation and variation of extrahepatic bile duct before gallbladder operationMethods The images of 100 cases having normal structure of gallbladder and extrahepatic bile duct were studied;the conformations and confluence sites were analyzedResults Among the 100 cases,97 cases had clear images of extrahepatic bile duct (97%),3 cases with large amount of air bulbs in bile duct because of the laxation of the lower common bile duct still had clear images of the general conformation of extrahepatic bile duct,87 cases had clear images of gallbladder and cystic duct (87%),13 cases (13%) had partial images of gallbladder or cystic ductConclusions ERCP can clearly show out the conformation and variation of extrahepatic bile duct and cystic duct and it is of important value before gallbladder operation

目的 通过对100例胆囊及肝外胆管正常结构尚存在的患者ERCP图像资料进行归纳和分析,探讨胆囊手术术前了解肝外胆道系统形态及变异的重要性。方法选出100例胆囊及肝外胆管正常结构尚存在的患者图像,对其形态、汇合位置进行分析。结果 100例患者图像中肝外胆管显示清晰者97例(97%),3例因胆总管下端开口松弛导致大量气泡进入胆道,但肝外胆管大体形态显示尚清晰,胆囊及胆囊管显示清晰者87例(87%),13例(13%)仅部分显示胆囊或胆囊管。结论 ERCP可以清晰显示肝外胆管及胆囊管的形态及变异情况,对于胆囊手术术前了解肝外胆道系统形态及变异有重要价值。 ERCP;胆囊管;肝外胆管

Results: MR demonstrated capsule wall and papillary solid lesions in one case with cystic and solid lesions of hepatobiliary cystadenoma. Poly cystic form tan if different sine in sew case, capsule wall and septation was thick, part of capsule wall was obviously thickened and nodes form, intrahepatic bile duct was dilated, large poly-antrum cystic keen form structure in one case, capsule wall and septation were smooth, part of capsule wall was uniformly thicken, capsule wall, septation, mural nodus form and solid lesions in three cases wee all slightly hyperintense on T2WI and slightly hypointense on T1WI. Part of cyst fluid was hypointense on T2WI the diameter if tumor ranged from 3.4cm to 13.5cm. Part of capsule wall, septation, solid lesions and mural nodus west obviously enhanced in arterial phase in three cases, the extent of enhancement showed a little degrade in port vein phase, balance phase and delay phase, but dense to liver parenchyma at synchronization.

结果:3例肝内胆管囊腺瘤中1例呈囊实性结构,可见囊壁及乳头状实性肿块;1例为多个大小不等的多房囊状结构,囊壁及分隔光滑,囊壁局部明显增厚,有壁结节,周围见轻度的肝内胆管扩张;1例为巨大的多房囊状结构,囊壁及分隔光滑,局部均匀增厚;3例中的囊壁、分隔、壁结节及实性部分均呈T2WI稍高信号、T1WI稍低信号,囊内液性部分均呈T2WI高信号、T1WI低信号;肿瘤瘤体大小径线范围3.4~13.5cm.3例肝内胆管囊腺瘤中囊壁、分隔、实性肿块和壁结节动脉期均明显强化,门脉期、平衡期及延迟期强化程度略减低,强化程度均高于同期肝实质。

Fourteen cases were converted to laparotomy (including 4 cases of type I Mirizzi syndrome, 4 cases of type II which all converted to laparotomy. 2 cases with the location of cystic duct into the common bile duct much lower than normal one, 2 cases with the confluence of cystic duct and cho ledoch locating in the posterior wall of choledoch. 1 case with a public wall shared for about 2 cm between the cystic duct and the choledoch).

结果 全组90例,术中中转开腹14例(包括Mirizzi综合征Ⅰ型4例Ⅱ型4例全部中转;胆囊管汇入胆总管过低2例;胆囊管开口于胆总管后壁2例;胆囊管与胆总管共同一侧壁,并并行约2 cm 1例;右肝管汇入胆囊管1例,开腹术中证实)。

Department of Neurosurgery, Shenzhen Second People's Hospital, Shenzhen Guangdong 518035, ChinaAbstract: Objective: To study the curative effect of stereotactic intracystic irradiation of treatment of cystic and cystsolid craniopharyngioma guided by CT or MRI. Methods: After cystic liquid was absorbed, colloid chromic phosphate was injected in the cystic part of the patients with cystic or cystsolid craniopharyngioma under CT or MRI.

对12例囊性和囊实性颅咽管瘤的囊性部分行CT、MRI 引导立体定向吸除囊液、注入胶体磷酸铬,待瘤囊缩小远离视神经等重要结构后,施行伽玛刀治疗。

Autosomal dominant polycystic kidney disease , one of the most common monogenetic human disorders, is characterized by the formation and progressive expansion of multiple cystic lesions, which compromise the function of normal renal parenchyma and lead to nearly 10% of cases of end-stage renal failure in adults.

中文题名角质细胞生长因子在ADPKD肾囊肿组织中的表达及对囊肿衬里上皮细胞增殖作用的研究副题名外文题名 Expression of keratinocyte growth factor in ADPKD cystic tissue and effect of proliferation on ADPKD cyst-lining epitheliar cells 论文作者刘沙勤导师梅长林朱有华教授学科专业内科学研究领域\研究方向学位级别博士学位授予单位第二军医大学学位授予日期2002 论文页码总数104页关键词角质细胞生长因子肾病囊肿衬里上皮细胞株肾囊肿馆藏号BSLW /2003 /R692 /1 ADPKD是人类为之付出昂贵代价的一种全身性遗传性疾病,是引起慢性肾功能衰竭的第四位病因,在临床上以肾脏满布大小不一并不断增大的囊性液泡、最终引起肾功能进行性损害为特征性的改变。

Objective:to explore the evaluation of color doppler ultrasonography in differential diagnosis of renal cystic disease.methods:theultrasonographic finds of cystic renal cancer in 4 cases,renal cyst in 30 cases, renal tuberculosis in 3 cases,nephropyosis in 8 cases,renal hydatid in 2 cases were analyzed.compared with each other in size,shape,edge, echo of cyst wall and cyst water,intracapsular membrane,blood flood.results:two-dimensional and color ultrasonography are helpful in showing the characteristic of structure and blood flow.the signal of blood flow can be found in cystic wall.node of cystic wall and intracapsular membrane of cystic renal cancer.the rate ofintracapsular membrane and node of cystic wall is higher than nephropyosis,renal tuberculosis and cystic renal disease.

目的:探讨彩色多普勒超声在肾脏囊性病变鉴别诊断中的价值。方法:对临床和病理证实的4例囊性肾癌,8例肾脓肿,2例肾包虫,3例肾结核,30例肾囊肿的二维超声及彩色多普勒超声表现进行了分析,对每例病灶的大小、形态、边界、囊壁回声、囊液回声、囊内分隔及彩色血流的有无、性质进行比较。结果:二维超声和彩色多普勒超声可以反映肾脏囊性病变的结构特征及血流特征。

The appearances of nonvascular lesions were as the following : solitary, huge cystic lesions with wall and septa obvious enhancement were found in malignant enbryonal sarcoma; mixed density mass with necrotic cystic change and solid portion enhanced obviously in carcinosarcoma; intrahepatic huge low density, cystic changes, calcification and margin enhancement were found in leiomyosarcoma.

血管源性表现为肝内多发低密度灶,强化明显,非血管源性表现为肝内巨大单发囊性病灶,增强囊壁和分隔明显强化;癌肉瘤表现为混杂密度肿块伴有坏死囊变,增强实质部分强化;平滑肌肉瘤表现为肝内巨大低密度病灶,可伴有囊变及钙化,增强见边缘强化。

Cystic lymphangioma of intestine and mesentery is a rare cystic disorder of abdomen; most of them are multi-leaved and plurilocular thin wall cysts. CT scanning can precisely display the morphologic characteristic of the pathological changes, provide relevant diagnostic evidence and help to differentiate from other cystic diseases.

肠及肠系膜囊性淋巴管瘤是腹部少见囊性病变,多呈分叶状、多房性薄壁囊肿,CT能够准确地显示病变的形态学特徵,并能够提供相应的诊断依据,帮助与其他囊性疾病鉴别。

Results:In this group there were 5 mucinous cystadenoma; 4 serous cystadenoma; 4 teratoma; 2 lager ovarian cyst; 4 subserous leiomyoma of uterine. The massive cystic-solid tumor with irregular cystic wall was seen in mucinous cystadenoma and serous cystadenoma; Teratoma appeared non homogenous density with fat density mass; Subserous leiomyoma of uterine showed large cystic tumor with clear edge, and the size of uterine was normal.

结果:5例卵巢浆液性囊腺瘤,4例黏液性囊腺瘤,CT表现为腹盆腔内巨大囊性或囊实性肿瘤,囊壁厚薄不均;4例卵巢畸胎瘤,CT表现为盆腔巨大肿瘤内部密度不均,可见脂肪密度影;卵巢巨大囊肿2例,CT表现为腹、盆内巨大单囊状肿物;4例浆膜下子宫肌瘤,CT表现为盆腔内巨大囊性肿物,边界清晰,子宫大小正常;1例阔韧带平滑肌瘤,CT表现为密度不均匀的实性肿物,增强扫描强化不均。

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