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Objective To investigate whether there are significant changes of the thalamus and corpus striatum in patients with Parkinson's disease using the proton magnetic resonance spectroscopy. And to evaluate the effectiveness in using this technique in the area of the pathophysiologic process and the diagnose of PD.

目的 探索帕金森病（Parkinson's disease， PD）病人丘脑和纹状体质子磁共振波谱变化，评价质子磁共振波谱技术用于帕金森病的诊断和病理生理研究的价值。

The expression of ICAM-1 and P-selectin mRNA and protein in ischemic cerebral cortex and corpus striatum in rat was observed after 1 h of cerebral ischemia and 3,6,12,24 and 48 h of reperfusion by in situ hybridizatioin and immunohistochemistry.

脑缺血区的毛细血管内皮细胞表达ICAM-1和P—selectinmRNA发生于脑缺血／再灌注后3h，ICAM—1mRNA在脑缺血／再灌注12h达到高峰（组内比较，P〈0.01）；P—selectin mRNA高峰出现在脑缺血／再灌注6-12h（组内比较，P〈0.01）。

Relative and absolute blood flow in the corpus striatum were determined using the laser Doppler flowmetry and the autoradiography diffusible tracer technique, respectively.

大脑纹状体的相对及绝对血流量是各利用雷射都卜勒仪及自动放射显影可扩散追踪剂方法测量得到。

By the computer 3D technique, a 3-D stereotactic morphology of the corpus striatum, marginal division and globus pallidus was thus reconstructed.

建立了大鼠脑纹状体、边缘区和苍白球的三维立体结构。

In addition to the pons positive neurons were also found in cerebellum, most nucleus of thalamus and hypothalamus, and corpus striatum of chicken.

鸡脑阳性神经元除广泛分布于脑干外，小脑、丘脑的多数核团、下丘脑的背侧核、腹侧核和后核以及大脑纹状体等多数脑区也有一定分布。

RESULTS Compared with normal control group, HVA, 5-HT and GSH contents, and SOD activity in corpus striatum of model mice decreased, and MDA content increased significantly. Otherwise, numbers of Bcl-2 and caspase 3 immune reaction positive cells in substantia nigra increased significantly.

结果 与正常对照组比较，模型组小鼠脑内纹状体HVA，5-HT和GSH含量显著下降，SOD活性下降，MDA含量明显升高；黑质致密部Bcl-2和caspase 3免疫阳性细胞数增加。

Objective To investigate the effects of subthalamic nucleus -deep brain stimulation on expression of dopamine and adenosine 3'5'-monophosphate-regulated phosphor-protein (DARPP-32) and its phosphorylated proteins in corpus striatum of rat models with levodopa-induced dyskinesia.

目的 探讨丘脑底核高频电刺激对帕金森病异动症大鼠纹状体区多巴胺和cAMP调节的磷蛋白(DARPP-32)及其磷酸化蛋白表达的影响。

The protection of VOA on brain may relate to the release of monoami neurotransmitters in corpus striatum increased, oxidative stress alleviated and neuronal apoptosis in substantia nigra reduced.

VOA的脑保护作用可能与其增加脑内纹状体单胺类神经递质释放、减轻氧化应激反应以及减少黑质致密部神经元凋亡有关。

Four weeks later, 69 Parkinson disease model s were randomly divided into 3 groups:①Control group(n=24):4.5 μL normal saline was injected into head of caudate nucleus of right-side corpus striatum.

取SD雄性大鼠，右侧中脑黑质致密区注入6-羟基多巴(2g/L)3μL制备帕金森病模型，4周后将69只成功帕金森病模型随机分为3组：①对照组24只：右侧纹状体尾状核头部注入生理盐水4.5μL。

The activity of NF-κB is downregulated and the mRNA expression is up-regulated. in the prefrontal cortex, hippocampus and corpus striatum in the hypoglutamatergic schizophrenia model rats which indicate NF-κB might be involved in the pathophysiology of schizophrenia.

谷氨酸能低下精神分裂症模型大鼠前额皮质、海马、纹状体NF-κB的活性受到了抑制，而mRNA表达上调，提示NF-κB可能参与了精神分裂症的病理过程。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。