查询词典 convulsant

Results CCK possesses the ability to suppress the convulsant effects of convulsants. CCK8 is able to reduce the neural damage caused and delay the neural aging. CCK antagonists play an important role in human pain transduction.

结果 CCK作为神经递质能够拮抗致痫剂的致痫作用；CCK8还能够对抗神经元的手术和化学损伤以及延缓神经元老化；CCK在痛觉传导过程中起到了重要的整合作用。

Two hours later, the convulsant mice were anesthetized deeply and fixed by transcardiac perfusion for Immunohistochemistry to detect c-Fos expression.③ Comparison of neurotoxicity induced by CD50 of three agents.

将发生惊厥的小鼠妥善标记，2 h后制作冰冻冠状切片，检测神经元核蛋白c-Fos的表达，镜下计算不同区域表达c-Fos的棕黄色颗粒数目，每个颗粒代表1个神经元。

Result: Both doses of SAE and verapamil ig all raised the convulsant threshold of phenytoin-resistant rats (480.38±18.48)μA, there were statistical differences ( P .05) compared to themselves before drugs-treated.

结果：全蝎乙醇提取物2种剂量及维拉帕米，均可使耐苯妥英钠大鼠惊厥阈值(480.38±18.48)μA明显升高，与惊厥模型组和耐苯妥英钠惊厥模型组相比均有显著性差异( P 。01)。

To address this issue we measured the plasma CRH concentration in developing rats received kainic acid, a convulsant agent which exerts behavioral and electrophysiological seizure activities by activating at kainate receptor and N-methyl-D-aspartate receptor.

近年来许多研究发现细胞激素具有调节内分泌的功能，并参与许多中枢神经系统疾病的过程进展，基於上述这些原因，为更能深入了解CRH在癫痫所参与的病理机转，我们利用红藻胺酸引发幼鼠产生抽搐藉以探讨CRH和细胞激素在周边或脑中的表现情形。

Methods Three doses of etomidate were administered intraperitoneally. Five minutcs later, convulsion was induced by electricity or drugs . The convulsant latency, duration of tonic state, incidence of convulsion, mortality and survival time were noted.

以电刺激或致惊剂〔士的宁、N-甲基－D-天冬氨酸、利多卡因〕建立不同类型的小鼠惊厥模型，观察腹腔注射3种剂量的依托咪酯对小鼠强直性惊厥潜伏期、持续期、惊厥发生率、小鼠死亡率以及小鼠存活时间的影响。

Convulsant ; picrotoxin ; penicillin ; kainic acid ; GABA A receptor

惊厥；印防己毒素；青霉素；红藻氨酸； GABAA受体

Days after a convulsant dose of KA, the seizure susceptibility were found in KA+NS group and enhanced in KA+PL017 group, whereas significantly decreased in KA+β-FNA group (p.01).β-FNA prolonged the latency and reduced the stage of seizures in dose-dependent manner.

结果显示，一次给予惊厥剂量KA后7天，KA+NS组的癫癎发作敏感性形成；MORs激动剂组（KA+PL017）动物出现癫癎发作敏感性增强；与上述两组比较，MORs拮抗剂组动物癫癎发作敏感性明显降低（p.01），β-FNA以剂量依赖方式延长癫癎发作的潜伏期、降低发作级别。

The seizure sensitive rats were made by subcutaneous injection of a convulsant dose (10mg/kg) of KA. Normal saline , PL017 or β-FNA were infused constantly into ventral hippocampus of awakened and freely moving animals for 7 days by mini-osmotic pumps. 7 days later, all rats were given subcutaneously with subconvulsant dose of KA.

皮下注射惊厥剂量（10mg/kg）的KA制备颞叶癫癎模型的癫癎发作敏感大鼠，采用微渗透泵技术分别将生理盐水、PL017和β-FNA连续7天恒速注入清醒自由活动的上述动物的腹侧海马内。7天后皮下注射阈下剂量（5mg/kg）KA检测癫癎发作敏感性形成情况。

This study demonstrated that KA administration in a convulsant dose could result in spontaneous recurrent seizures and permanent disturbances of behavior and cognition in old rats (P25、P60) which brains were in mature. However temporal and reversible effects occurred in rat pups (P5、P15) in immature brain.

一次给予惊厥剂量的KA可诱发脑发育成熟大鼠（P25、P60）出现自发癫痫发作，但在脑发育未成熟大鼠（P5、P15）中未见有自发癫痫发作；KA致痫对脑发育成熟大鼠造成的认知行为异常持久而不可逆，但对脑发育未成熟幼鼠认知行为的影响则持续时间短而可逆。

Methods Three doses of etomidate were administered intraperitoneally.Five minutcs later,convulsion was induced by electricity or drugs ［strychnine.N-methyl-D-aspartate.lidocanine］.The convulsant latency,duration of tonic state,incidence of con-vulsion,mortality and survival time were noted.

以电刺激或致惊剂〔士的宁、N-甲基-D-天冬氨酸、利多卡因〕建立不同类型的小鼠惊厥模型，观察腹腔注射3种剂量的依托咪酯对小鼠强直性惊厥潜伏期、持续期、惊厥发生率、小鼠死亡率以及小鼠存活时间的影响。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。