查询词典 contiguous receptor

The results suggest that papillary renal cell carcinoma with PNA-receptor originate from lower nephron. PNA-receptor may be related with the biologic behavior of tumor cells.

提示一些PNA受体阳性表达的乳头状肾细胞癌可能起源于下肾单位，PNA受体与肿瘤细胞恶性生物学行为有关，PNA染色可作为乳头状肾细胞癌的预后指标。

The relation between different BMPRIB genotype in Small Tailed Han sheep and FSH receptor or LH receptor mRNA levels during the oestrum was studied by semi-quantity PCR.

4利用半定量PCR技术研究发情期小尾寒羊BMPRIB基因型与ERα和PR的mRNA表达量的关系。

The result showed FSH receptor mRNA levels from the right ovary of BB (1.14 ± 0.11) ewes were higher than those of AA (0.44 ± 0.11) and AB (0.36 ± 0.08) ewes (P.01); LH receptor mRNA levels from the right ovary of BB (0.42±0.02) ewes were significant higher than those of AA (0.23 ± 0.02) and AB (0.25±0.04) ewes (P.01), but there were no significant difference in the left ovary among the genotypes during the oestrum.

结果显示：在发情期BB型右侧卵巢PR的mRNA水平(0.81±0.10)显著高于AA(0.43±0.10)型(P.05)，左侧卵巢各基因型间无差异。

Objective To explore the relationship between transforming growth factor-β1 and estrogen receptor with the occurrence of stress urinary incontinencethrough analysis on transforming growth factorβ1(TGF-β1) and estrogen receptor in paries anterior vaginase.

目的探讨绝经后压力性尿失禁患者盆底支持结构转化生长因子β1(TGF-β1)、雌激素受体与SUI发生的关系。

This dissertation for Ph. D. degree focuses on the design, synthesis and biological evaluation of novel active compounds against three important anti-metabolic drug targets, dipepetidyl peptidase IV, peroxisome proliferator-activated receptor γ, and farnesoid X receptor.

中文摘要本论文在综合运用传统药物设计理论、计算机虚拟筛选方法和现代有机合成技术的基础上，针对三个代谢类疾病的靶标进行药物设计、化合物合成与活性评价等研究工作。

The receptor binding experiment agreed to the result of Pettit's experiment, which suggested that Asp〓 and Gln〓were essential to receptor binding.

上述结果表明这二株突变体均保留了与受体结合的活性，这与Pettit等分析Asp〓、Gln〓对受体结合很重要的结论是一致的。

Protease treatment of the plasma membranes could abolish the binding but NaIO_4 and glycosidase could not, indicating that nsLTP144 bound to plasma membranes protein without carbohydrate moiety. Using the homobifunctional cross-linking regent bissuberate (BS~3) and rice plasma membranes incubated with ~(125)I-Trx-nsLTP144, we identified, after SDS-polyacrylamide gel electrophoresis and autoradiography, a putative protein receptor on the rice plasma membranes with the molecular mass around 60 kDa. NsLTP144 can not trigger extracelluar alkalization in arabidopsis, but can abolish the extracellular alkalization effect of phytopathogen elicitor cryptogein, suggesting that cryptogein and nsLTP144 may bind to the same membrane protein. In vitro pull-down assay showed that nsLTP144 interacted with OsCaM1, a possible extracellular calmodulin, implying that nsLTP144 and OsCaM1 could function in the same signal transduction pathway. These results shed light on revealing the roles of nsLTP in vivo and make it promising to finally characterize the plasma membranes receptor of nsLTP.

发现~(125)I-Trx-nsLTP144、~(125)I-Trx-nsLTP110与水稻细胞质膜均具有特异性结合，而且结合是饱和性的、可被竞争的，符合配体-受体结合的典型特征，同时用于对照实验的蛋白质~(125)I-Thioredoxin没有此特性，表明水稻细胞质膜上存在nsLTP的受体；利用可氧化糖基的NaIO_4和水解糖基的N\'-糖苷酶F处理水稻细胞质膜，再进行结合实验，结合活性几乎不受影响；而利用胰蛋白酶处理细胞膜则使得结合能力几乎完全丧失，表明其受体为没有经过糖基化修饰的蛋白质；利用交联剂BS~3交联配体一受体后，再进行SDS-PAGE分离和放射自显影，结果显示水稻细胞质膜上的nsLTP受体中有一个60kDa的蛋白质可以与nsLTP144发生特异性的结合，可能是其受体；细胞外碱化实验表明，nsLTP144不能促使拟南芥原生质体细胞培养液的细胞外碱化反应，却能猝灭来自植物病原菌的激发子Cryptogein刺激拟南芥原生质体产生的细胞外碱化反应，表明nsLTP和Cryptogein结合细胞膜上相同的位点，保护了植物细胞免受Cryptogein导致的细胞程序性死亡，并诱导系统获得性抗性的产生；体外Pull-down实验表明，nsLTP144和水稻的OsCaM1具有相互作用，暗示了nsLTP144和OsCaM1可能同在一个信号通路上起作用。

Considering together with our previous report about HSS regulation on EGF receptor, these results strongly suggest that the proliferatory effect of HSS on hepatic carcinoma cells is presumedly related with EGF receptor-mediated signal transduction.

鉴于我们已报道HSS上调EGF受体蛋白和基因表达这一事实，本实验结果进一步说明， HSS促人肝癌肝细胞增殖与其调节EGF受体介导的信号分子传导过程相关。

Objective It is to investigate the clinical significance of the expression of estrogen receptor and progesterone receptor in Endometrioid carcinoma.

目的研究雌激素受体、孕激素受体在子宫内膜样癌组织中的表达及临床意义。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况，详细介绍了新型喹唑啉类表皮生长因子受体抑制剂，着重研究了该类化合物的合成，设计并打通了合成路线，同时又合成了25个新化合物。

A carrier gas such as nitrogen is directed through line 20 and valve 22 to connect with line 26 and mix with the gas sample.

如氮气之类的载体通过管线20和阀22引入，与管线26相通，与气体样品混合。

But for the most part, knaves and parasites had the command of his fortune

然而支配他的家产的大多是恶棍和寄生虫。