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A detail comparison demonstrates that such preconditioned IbpB is distinguished from the non-preconditioned IbpB by a remarkable conformational transformation, including a significant increase in the flexibility of the N- and C-terminal regions, as well as enhanced dynamic subunit dissociation/reassociation.

我们的比较研究表明，这样的经过热休克预处理过的 IbpB蛋白与未经历过热休克条件的蛋白之间存在很大的构象上的差异，包括前者在N-和C-末端区域可曲性的明显增强，以及亚基动态分离/重结合的加强。

Completely different crystal structures and morphology were shown in the meltdrawn films of two kinds of tacticity of sPP. A continuous conformational transform from the 〓 into the of sPP was induced by further stretching. While the zigzag conformation can retransform back to helical 〓 one after annealing above 80℃, the mechanism of conformation transform has been introduced.

Petermann教授学科专业高分子化学与物理研究领域\研究方向学位级别博士学位授予单位中国科学院长春应用化学研究所学位授予日期2001 论文页码总数114页关键词聚丙烯聚丁烯共聚物聚α-烯烃馆藏号BSLW /2003 /O632 /3 用电子显微学、电子衍射、DSC和FTIR等技术对聚α-烯烃及其共聚物的晶体结构和相转变行为进行了系统地研究，包括间同立构聚丙烯、全同立构和间同立构聚丁烯-1（iPB-1，sPB-1）、以及丙烯-丁烯-1间同立构共聚物。

APSll component, the PsbS protein, is proved to play a key role in NPQ. Our experimental results demonstrate that PsbS is located within PSll supercomplex and abuts LHCll. Also, it cannot quench excitation energy directly, but indirectly by its conformational changes in soybean leaves.

我们的研究表明，PsbS与LHCll相邻，在大豆叶片中PsbS在NPQ中发挥作用的机制与主要依赖叶黄素循环的植物不同，它不是直接猝灭能量，而是通过构象变化在NPQ中发挥作用。

The mechanism of clonidine conformational isomerization and tautomeric reaction has been studied and the geometric parameters of transition states have been located by B3LYP/6-31G**.

为了考察氯苯的共轭效应对可乐定互变异构体稳定性的影响，在B3LYP/6-31G**水平上，研究了2-氨基-2-咪唑啉的互变异构化反应机理。

It has also been discovered that, before complete purification, the synthetic HWTX-Ⅰ, after oxidative treatment, showed wider and more asymmetric peaks than the native HWTX-Ⅰ that was denatured and then renatured under the same experimental conditions, which suggests that there is even greater conformational unhomogeneity in the synthetic HWTX-Ⅰ.

推测除了在合成HWTX-Ⅰ复性过程中有少数分子发生二硫键错配外，还有部分分子在固相合成中发生了消旋作用，需要交替采取多种色谱法才能完全分离纯化复性后的合成多肽产物。

Through the comparison analysis for two MD simulation data, it was found that for the system with Zn2+ ions and phenol, the conformational flexibility of insulin hexamer was decreased.

用分子动力学模拟方法设计了两个模拟时间为600 ps的对比计算机模拟实验，研究了R6态的胰岛素六聚体在水溶液中的构象柔性。

The point mutations of the 12th coden of ras gene and p53 E5 and E7 gene were studied in 40 cases w ith laryngeal squamous cell carcinomas by PCR-SSCP(polymerase chain reaction-s ingle stranded conformational polymorphism).

应用多聚酶链反应-单链构像多态性分析方法分析40例喉鳞状细胞癌H-ras，K-ras，和N-ras基因的第12密码子，p53 基因第5，7外显子中点突变的情况。

The active conformation of protoporphyrinogen IX (substrate of protoporphyrinogen oxidase) has been established using the Distance Comparisons method. In this paper, four different conformational molecules of Protogen IX and crystal molecule of diphenylethers are analyzed by comparing their geometry parameters. The results show the lower energy active conformation from the DISCO model is more reasonable.

我们曾利用距离比较法确定了原卟啉原氧化酶的底物—原卟啉原IX的活性构象，本文从构象分析的角度对4种不同构象的原卟啉原IX分子与二苯醚类分子的晶体学构象进行了几何参数的比较和分析，结果进一步证实了距离比较法所确定的活性构象更为可靠。

In the reasonable drug molecular design,analyzing the conformations of the substrate without three-dimension structure and confirming its active conformation are very important to illustrate the spatial shape and active site of target enzyme. The active conformation of protoporphyrinogen IX substrate of protoporphyrinogen oxidase has been established using the Distance Comparisons DISCO method. In this paper, four different conformational molecules of Protogen IX and crystal molecule of diphenylethersAF are analyzed by comparing their geometry parameters. The results show the lower energy active conformation from the DISCO model is more reasonable.

在合理药物设计方法中，当靶标酶的三维结构未知时，对其底物进行构象分析，特别是确定其活性构象，对阐明靶标酶活性中心的空间形状和作用位点具有十分重要的意义我们曾利用距离比较法确定了原卟啉原氧化酶的底物—原卟啉原IX的活性构象，本文从构象分析的角度对4种不同构象的原卟啉原IX分子与二苯醚类分子的晶体学构象进行了几何参数的比较和分析，结果进一步证实了距离比较法所确定的活性构象更为可靠

This conformational change is reversible. So, the temperature-/pH- sensitive graft copolymers can be obtained by copolymerizing PNIPAM with MAA in a certain manner.

甲基丙烯酸是一种亲水性的单体，将它以适当的方式与PNIPAM聚合，可以得到既有pH敏感性也有温度敏感性的聚合物。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。