查询词典 conformational

This effect is shown to be correlated with the conformational changes of acyl backbone induced by aniso-damine.

采用拉曼差光谱的方法，进一步研究了药物的苯环与酸性磷脂的疏水相互作用。

The 1:1 binding of heparin to antithrombin III appears to cause a conformational change in the protein that greatly increases its ability to inhibit clotting.

肝素与antithrombinⅢ的1：1的结合似引起此蛋白质的构象改变，从而增加其抑制血液凝固的能力。

The 1:1 binding of heparin to antithrombin III appears to cause a conformational change in the protein that greatly increases its ability to inhibit clot ting.

肝素与antithrombinⅢ的1：1的结合似引起此蛋白质的构象改变，从而增加其抑制血液凝固的能力。

The conformational study of arginine is the most challenging due to its large number of rotational degrees of freedom.

由于其众多的自由度而成为氨基酸理论计算中很富有挑战性的一个氨基酸。

Our goal is to establish a simple and effective empirical approach to calculate the conformational entropy and the binding free energy by analysis of J: protein interface.

我们的目的是通过分析蛋白质复合物的界面信息来拟合计算构象熵和结合自由能的简单有效的半经验模型。

Our goal is to establish a simple and effective empirical approach to calculate the conformational entropy and the binding free energy by analysis ofJ:protein interface.

我们的目的是通过分析蛋白质复合物的界面信息来拟合计算构象熵和结合自由能的简单有效的半经验模型。

It has been known that these diseases result from the conformational transition of a host-encoded prion protein to a β-sheet-rich conformer.

普昂疾病是一种传染性海绵样脑病变，此病是由内生的普昂蛋白发生构形变异、形成富含β结构的构形而造成。

In chapter 3, we systematically explore the conformational potential energy surfaces of aspartic acid in gas phase and calculate the concerned properties including geometry structure, IR spectra, conformer distributions, ionization energies and electron affinities.

在第三章中我们对天冬氨酸气相中的构型势能面进行了系统的探测，并研究了其相关性质，如几何结构、红外光谱、构型分布、电离能和电子亲合能。

To extract conformational motifs and construct fragmental libraries for peptide, it is important to analyze the structure of the conformational space of oligo-peptide.

研究蛋白质寡肽构象在构象空间中的分布情况，对提取寡肽模式并构建短肽库具有重要的意义。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。