查询词典 conformation

The conformation model of rhodanine fluorescence reagents was established.

初步建立了若丹宁类荧光试剂的构效关系，为系列若丹宁衍生物的合成提供理论指导。

We explore the relation between structure and activity , structure and toxicity from electronic structure and three—dimensional conformation in order to provide theoretical foundations for predicting the activity and toxicity of these chemical compounds, researching into mechanism of action and choosing safener.

通过比较四种均三氮苯类除草剂的红外光谱特征吸收的实验值和计算值，并运用规范不变原子轨道法GIAO法在RHF/6-31G水平上计算出西玛津的δ~1H-NMR和δ~(13)C-NMR，与实验值的对比统计分析，结果表明：用RHF/6-31G优化的分子构型最佳，AM1法次之，考虑到优化时间和研究的需要，我们在研究均三氮苯类除草剂分子的结构与活性关系时，为了进行深入、精确的理论研究，采用从头算RHF/6-31G进行优化；而对于此类化合物的结构与毒性的关系研究时，更注重分子的量子化学参数的相对值而非绝对值，因而采用AM1的方法。

Effects of steric hindrance and conformation on the properties of the polymer were investigated.

通过在聚合物中引入芴和联苯的结构以及在PPV单元上引入不同链长的侧基等研究了聚合物的几何构型以及位阻等因素对材料性质的影响。

To identify cytoskeletal proteins that change conformation or assembly within stressed cells, in situ labeling of sterically shielded cysteines with fluorophores was analyzed by fluorescence imaging, quantitative mass spectrometry, and sequential two-dye labeling.

从蛋白质的氨基酸序列来预测它的三维结构是计算生物学和计算化学长期面临的挑战。研究人员40多年前就知道蛋白质的结构完全是由其氨基酸序列决定的，但是用序列信息来做结构的预测极为困难。

By the method of polymerase chain reaction-single strand conformation polymorphism, this paper studied the genetic polymorphism of exon 1 and intron 1 in the aquaporin gene of seven species of Stipa in the meadow steppe, typical steppe, and desert steppe of Inner Mongolia.

以分布于内蒙古的草甸草原、典型草原、荒漠草原上的7种针茅属植物为材料，利用聚合酶链反应－单链构象多态性方法，分析了水孔蛋白基因的外显子1和内含子1的遗传多态性。

It was showed by synchronal fluorescence technique that AZP and 6-MP had effect on the conformation of BSA.

二者免疫抑制作用的机理相同，口服进入人体后，具有嘌呤拮抗作用。

UV of tannase suggested the effects of various alcohol on tannase conformation were different.

紫外吸收图谱说明不同脂肪醇对单宁酶的构象影响有差别。

By using multi-dimensional nuclear magnetic resonance method we have studied the folding mechanism of staphylococcal nuclease in vitro; the tertiary interactions for folding of SNase fragments into native-like conformation; the interaction between SNase N- and C-terminal subunits; the relationship of enzyme activity with folding and dynamic states of SNase; the structural properties of enzyme protein while exert its function. We have studied the internal motions of thermophilic Archaea protein Ssh10b and mechanism of its heat-resistance using the NMR 1H-15N relaxation and H/D exchange methods. We have determined the 3D solution structure of human translationally controlled tumor protein TCTP and the Ca2+-binding site; determined the 3D crystal structure of human mitoNEET, a novel protein from distinct groups of iron-sulfur proteins; determined the 3D solution structure of a novel chromatin protein Cren7. Determination of SNase-DNA and Archaea protein-DNA complex structures are in progress.

运用异核多维核磁共振方法研究了金黄色葡萄球菌酶体外折叠机制，酶蛋白片段体外折叠成类天然溶液三维构象的三级相互作用力，酶蛋白亚基间的相互作用，酶蛋白的折叠以及内运动状态与酶活力的关系，酶蛋白发挥功能时的结构特性；运用NMR的1H-15N 驰豫和H/D交换方法研究了嗜热古菌蛋白质Ssh10b双体结构内运动特性，热稳定性机制；确定了人翻译控制的肿瘤蛋白TCTP蛋白的溶液三维结构及其钙离子的结合部位；确定了一类新的铁硫蛋白家族蛋白人线粒体膜上mitoNEET蛋白的晶体结构；确定了一个新型的染色质蛋白Cren7的溶液三维结构；正在研究金黄色葡萄球菌酶及嗜热古菌蛋白质与DNA复合体的溶液三维结构。

Here we report the crystal structure of the parainfluenza virus 5 F protein in its prefusion conformation, stabilized by the addition of a carboxy-terminal trimerization domain.

首先，它们以一个亚稳态的形状出现，这个形状能储存进入细胞所需的能量；然后，该蛋白形状所发生的不可逆转的变化促成膜的融合。

In this study, nonionic surfactant sorbitan trioleate (Span 85) was modified with Cibacron Blue F-3GA to become an affinity surfactant (CB-Span 85) and to form affinity-based reversed micelles while dissolved in hexane. Since the CB molecule possesses a specific conformation that mimics nicotinamide adenine dinucleotide, it can bind strongly and specifically to a wide range of nucleotide-dependent enzymes such as dehydrogenases and kinases. Moreover, high protein transfer efficiency in the reverse micelles can be easily achieved by controlling the ionic strength of the aqueous phase.

本实验使用非离子型界面活性剂Span 85与蓝色染料分子Cibacron Blue F-3GA结合，形成具有亲和性的界面活性剂 CB-Span 85，由於CB染料分子具有与NAD+相似的结构，可与含核苷酸部位的蛋白质具有亲和力，将CB-Span 85溶於有机溶剂形成反微胞相，可有效的提高反微胞的选择率，可以只控制离子强度来调节蛋白质进出反微胞的效率。

Finally, according to market conditions and market products this article paper analyzes the trends in the development of camera technology, and designs a color night vision camera.

最后根据市场情况和市面上产品的情况分析了摄像机技术的发展趋势，并设计了一款彩色夜视摄像机。

Only person height weeds and the fierce looks stone idles were there.

只有半人深的荒草和龇牙咧嘴的神像。