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The concentration of NO and NO2 increases with increasing of frequency and increasing of the distance between electrodes. Electrode polarity unconspicuously affects the concentration of NO and NO2. The distance between electrodes considerably affects radio of NO2 /.

结果发现:放电频率、电极间距对NO 和NO2的浓度影响显著, NO 和NO2浓度随放电频率和放电间距的提高而增加,电极极性对NO 和NO2浓度的影响不明显,电极间距对 NO2 /的比值影响明显。

The contents of proline and soluble protein in V. unguiculata seedlings were both increased with the rise of the seed-soaking concentration of triadimefon, with the concentration of 30 mg/L reaching the maximum.

豇豆幼苗的脯氨酸和可溶性蛋白质的含量均随三唑酮浸种浓度的升高而增加,30mg/L达到最大值。

The inhibition effect of chloroform fraction was the most potent, with the inhibition rate about more than 83% to 5 plant pathogenic fungi under the concentration of 15mg/mL. Under the concentration of 15mg/mL, the ethyl acetate fraction and n-butanol fraction thoroughly inhibited the growth of Alternaria solani and Valsa mali, with the inhibition rate up to 100%. The n-butanol fraction showed the highest potent virulence, with EC50 to Alternaria solani and Valsa mali about 0.09 and 0.279 mg/mL respectively.

其中氯仿部分的抑菌效果较好,当质量浓度为15mg/mL时,其对5种植物病原菌的抑制率均在83%以上;15mg/mL乙酸乙酯部分和正丁醇部分分别对番茄早疫病菌和苹果腐烂病菌有强烈且稳定的抑制作用,抑制率达100.00%,正丁醇部分对这两种菌丝生长抑制毒力最好,EC50分别为0.090和0.279mg/mL。

Results(1)At concentration of 0.002 5%,the KT50 is 4 min :0.002 5% is 3.77(3.40-4.15)min ;0.005% is 3.17( 2.88- 3.48)min;0.01% is 3.45(3.25-3.65)min ;(2)the LC50 is 0.000 530 9%(0.000 490 0%-0.000 575 2%);(3)the 100% mortality(24 hour) with the Dagongda concentration is at the rate of 0.002 5%;(4)when used as residual smearing,Dagongda can be keep its efficacy more than 270 days under room temperature;(5)The field tests,the killing rates of 0.03% Dagongda to Xenopsylla cheopis were 80.80% for 2 days and 93.87% for 29 days respectively.

2当药物浓度在0.0025%、0.005%、0.01%时,印鼠客蚤24h死亡率均为100%。(3)持效:药膜在室温和普通湿度下存放9个月后,药物浓度在0.0025%以上时,印鼠客蚤24h死亡率均为100%。(4)现场2d灭效:使用0.03%浓度对地面游离印鼠客蚤的校正灭蚤率为80.80%。(5)现场残效(29d):使用0.03%浓度对地面游离印鼠客蚤的校正灭蚤率为93.87%。

Plateau zokor is one of the blind subterranean mole rats, they spend their lives solely underground in sealed burrows. In their burrows, the concentration of oxygen is low while the concentration of carbon dioxide is high, and their concentrations fluctuated extremely following the seasons.

高原鼢鼠是青藏高原的一种地下鼠,终生生活于地下封闭系统的洞穴环境之中,洞道内氧气含量低而二氧化碳含量高,并且氧气和二氧化碳含量随季节变化发生大幅度波动。

PBMC treated with inhibitor N-tosyl phenylalanine chlormethyl ketone, Astragalus can increase the activity of NF-κ B and the concentration of IL-8 in patients with PNS. it also increases the the activity of NF-κ B in normal children , but can ' t affected the concentration of IL-8 in normal children. ConclusionIn patients with PNS , the activity of NF-κ B was up-regulated and the level of IL-8 was significantly elevated.

结果肾病患儿 NF-κ B 活性及 IL-8含量增高,2者呈正相关; IL-1β刺激后,黄芪降低肾病患儿 NF-κ B 活性及 IL-8含量、降低正常儿童 NF-κ B 活性而不影响 IL-8含量;用对甲苯磺酰-L-苯丙氨酸氯甲基甲酮抑制后,黄芪可提高肾病患儿 NF-κ B 活性及 IL-8含量、提高正常儿童 NF-κ B 活性;而不影响 IL-8含量。

However, higher concentration of CRP may increase the expression of protein and mRNA of inflammatory factor in endothelial cells; 2 Higher concentration of CRP may participate in the development of inflammatory process in endothelium by the mechanism that CRP induce cells apoptosis and activate signal pathway involved in cell proliferation. 3 CRP is the member of pentraxins family, in which two faces of pentamer form a special bi-phase structure: one face is ligand recognition phase; the other face is effector phase.

总结: 1CRP是一种保守蛋白,在正常生理水平下对内皮细胞没有明显的诱导炎症发生的作用,仅在高浓度条件下有可能诱导细胞炎症相关蛋白及mRNA的表达; 2高于生理水平的CRP对内皮细胞的致炎作用主要通过诱导细胞凋亡及激活细胞增殖相关蛋白信号通路的表达; 3CRP是一种双面五聚体蛋白,结构具有特殊的二相性,能够分别结合内皮细胞和E-LDL。

Results:We used different concentration of NDGA to dispose cancer cell independently.Accompanying the rise in drug's concentration,apoptosis rate of cells rose gradually,morphologic of cells became round,the volume became small and they abscised from the inner surface of the bottle.apoptotic body could be found through scanning electron microscope.

结果:不同浓度NDGA处理HT29结肠癌细胞,随着药物浓度加大,细胞形态变圆,体积缩小,从瓶壁上逐步脱落,肿瘤细胞凋亡率逐步上升,癌细胞阻滞于G0/G1期。

There were 15 pediatric ALL patients, which had received 50 times of chemotherapy with HD-MTX. The records about blood concentration of MTX and clinical conditions for 50 times chemotherapy were divided into two groups. Group I: contained 25 records of stand-risk patients, administering MTX 3.0g/m2; Group II: contained 25 records of mid and high-risk patients, administering 5.0g/m2. Continuous intravenous dripped MTX for 24th in both two groups, while implemented hydrating and alkalizing for 4 days. All patients were rescued 6 times through leucovorin, 15mg/m~2, since 12th after the end of MTX dripping. Then examined the blood concentration of MTX by fluorescence polarization immunoassay approach at 24h, 44h, 68h, at the same time inspected liver function, blood routine examination, the occurrence time and degree of toxicological reactions.

观察15例ALL住院患儿,接受大剂量MTX共50例次,按ALL危险度分2组,低危治疗组接受MTX剂量为3.0g/m2为I组;中高危治疗组接受MTX剂量为5.0g/m2为II组,连续静脉点滴MTX共24小时,同时给予水化碱化治疗,共4天,全部病例均在MTX滴注结束后12小时开始静脉推注四氢叶酸钙(leucovorin,LV)解救,15mg/m2/次,共6次,采用免疫偏振荧光法检测药物滴注24、44、68小时MTX血药浓度,同时检测两组病例的肝功、血常规,观察临床出现MTX毒副反应的时间及程度,观察每个病例毒副反应出现程度与MTX血药浓度关系,两组毒副反应程度比较,进行统计学分析。

Results: 1. The value of all experimental indexes decreased significantly after heat stress, and reached the lowest at the time 2-8 hours after heat stress. This indicates that the immunity of the mice is damaged to the largest extent at 2-8 hours after heat stress. 2. L-arginine supplementation with appropriate dose could remit the acute atrophying of thymus and spleen tissue caused by heat stress. 3. After L-arginine supplementation with appropriate dose, the lymphocyte proliferation, the level of concentration of IL-2 and * expression of IL-2R raised in the group with room temperature; in the heat stress group the level of three indexs decrease significantly. Furthermore, the decrease of the group given 1 .Smglg.bw L-arginine is the smallest. This result indicates that the concentration of 1 .Smglg.bw L-arginine supplementation could remit the depressment of the immunity caused by heat stress. 4. The [Ca2~] in activated thymocytes of the group with L-arginine -2- supplementation is significantly higher than that of the group with water supplementation. This indicates that L-arginine supplementation could protect thymoeytes of mouse under heat stress. We also found that the fluorescence intensity of [Ca2~] in activated thymocytes of the group given 1 .Smglg.bw L-arginine is the highest.

结果:1、热应激后小鼠的各项免疫指标均有显著性下降,其中在2.8小时降到最低,提示在这个时间段小鼠的免疫功能受到最大损害;2、适量补充精氨酸有助于缓解热应激导致小鼠胸腺和脾脏的急性萎缩;3、常温组,补充适量精氨酸后小鼠淋巴细胞增殖活性、IL-2的浓度及IL-2R的表达均有显著性上升,而热应激后三指标均显著降低,其中在精氨酸给予浓度为1.5mg/g.bw时三指标的降低程度最少,提示该浓度可最大程度缓解热应激对小鼠免疫功能的抑制;4、补充精氨酸组的活化胸腺细胞[Ca~(2+)]较给水组有显著性上升,说明精氨酸对热应激小鼠胸腺细胞具有保护作用,并发现在精氨酸给予浓度为1.5mg/g.bw时活化胸腺细胞的胞浆钙离子荧光强度达到最大;5、热应激后小鼠血清NO的浓度均有不同程度的上升,补充精氨酸后血清NO上升更加明显,但并非随精氨酸给予浓度的增加而增加。

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