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The order of elution, as well as the migration time and separation efficiency of these compounds changes with the acidity of the solution, which suggests the disassociation of the hydrogen on the secondary amino group in these compounds.

它不仅影响化合物的迁移时间和分离效率,还改变其出峰顺序,这与碱性条件下化合物仲胺基上氢的电离有关。

It is that:(1) the related compounds in Metronidazole Buccal Tablets prepared by Chongqing Medical College can be tested by determining (321nm) the total peak area of the impurities;(2) The related compounds in Metronidazole Disodium Phosphate for Injection prepared by Chongqing Medical College can be test by determining (254nm) the total peak area of the impurities and the peak area of the largest impurity;(3) Ceftriaxone polymer in Ceftriaxone Sodium for Injection prepared by Chongqing Keru Pharmacy Co.

结果如下:①用HPLC一UV法,在321nm处检测,用归一化法计算,控制各杂质峰面积的和,可检查重庆医科大学的注射用甲硝吟磷酸二钠中的有关物质:②用HPLC一UV法,在254nm处检测,控制杂质峰面积的和及控制最大杂质峰面积,可对重庆科瑞制药股份有限公司的注射用头饱曲松钠中的有关物质实施控制;③用HPLC一Uv法,在254nm处检测,按外标法计算,可检查注射用头抱曲松钠中的聚合物;④用紫外分光光度法,在277nm波长处测定吸收度,按C6H9N303的吸收系数为377计算每片标示百分含量,可测定重庆医科大学的甲硝哇口颊片的含量均匀度;⑤用紫外分光光度法,在277run波长处分别测定释放溶液20min、50min和90min的吸收度,按甲硝哇(C6H剥303)的吸收系数为377计算释放度,可检查重庆医科大学的甲硝哇口颊片的释放度。

Based on the endocrine disrupter characteristic of alkyl phenol compounds, the short chain alkyl phenol compounds still have estrogen hormone effect, and their environmental effect must be pay attention in the pollutant control of NP.

根据烷基酚类物质的内分泌干扰特性,短链烷基酚仍然具有雌激素活性,因此在壬基酚污染防治过程中应给与足够的重视。

The influence of each condition on the reaction speed and yield was studied, and the optimal conditions were: the ratio of the amount of substance of aromatic amine and heptafluoro-isopropyl iodine was 1:1.1~1.5, the amount of substance of sodium dithionite, sodium bicarbonate, aniline compounds were respectively 1.1~1.3, the amount of substance of phase transfer catalyst TBAB and aniline compounds was 0.05~0.1, the concentration of aniline compound was 0.5~1.0 mol/L, reaction temperature was 10~20 ℃, and the solvent was aether.

最佳结果为:芳胺与七氟异丙基碘的物质的量比1:1.1~1.5,连二亚硫酸钠、碳酸氢钠与苯胺的物质的量分别为1.1~1.3,相转移催化剂四丁基溴化铵与苯胺的物质的量比在0.05~0.1,溶剂总用量使苯胺浓度在0.5~1.0 mol/L;反应温度10~20℃;溶剂采用乙醚。取代基供电子性越强,反应时间越短,产率越高;氨基的对位优先反应,氨基的邻位较难发生反应;且七氟异丙基总是优先取代在芳环电子云密度较高的位置上。

Because both ions in A and B sites of these compounds can be substituted by other ions with different electrovalence and radius in a wide range, their dielectric property is adjustable and can be optimized in a large scale. This implies that new type MWDC with advanced dielectric property may be exploited from these compounds and widely used.

该类化合物由于A、B位均可能被电价与半径不同的阳离子在较宽的范围内取代,所以其介电性质有较大范围的调节与优化的可能性,因此从该类化合物中极有可能开发出具有广泛应用前景的新型高性能微波介质陶瓷材料。

Taking Au-Ag intergrowth compounds as an example this paper has reached the following conclusions. In the Au-Ag compounds of differem types of gold deposits as sequemially replaces Au, making up a continuous isomorphous series. The content of Au and Ag in native gold forms a regular pattern. The development of native gold and that of electrum have something to do with different types of gold deposits respectively. Abundances of trace elements in Au-Ag minerals are controlled by geological settings and geochemical fields. The above study provides new geological information and a new method for the study and exploration of gold deposits.

本文以金银互化物的研究为例,讨论了在不同在因类型矿床中,金-银构成一个连续的类质同象系列,且变化是有规律可循,其微量元素的含量与该矿床成矿地质环境和相应的地球化学场有关,从而为找矿提供了新的地质信息,拓宽了寻找同类伴生元素矿床或发现新类型矿床的途径。

It is some uncertain chlorinated compounds not pentachloro ethane and/or hexachloro ethane however that can be detected in most EOM from sedimentary rocks, indicating that the interaction of copper with chloroform can be restrained by EOM and/or they may be transformed into other chlorinated compounds.

铜对氯仿的催化会影响氯仿沥青的定量和组成。

As stated previously, we have assumed that all MCs are equipotent and we are treating them as a group of compounds and not as single compounds.

如前所述,我们认为,所有主持人都equipotent ,我们对待他们作为一个群体的化合物,而不是单一的化合物。

Based on the previous literatures, the following major innovation works were carried out in this dissertation:(1) The derivatization reaction conditions of ephedrine and pseudoephedrine with sensitive derivation reagent in aqueous system were studied and two new methods were developed for the assay of them by microemulsion electrokinetic chromatography and micellar electrokinetic chromatography with LIF detection. The sensitivity and analysis times were greatly improved compared with the previous reports;(2) A new method of CZE with indirect LIF detection was developed for the simultaneous determination of six coumarin compounds (esculin, esculetin, isofraxidin, genistein, naringin and sophoricoside) with fluorescein as the probe. The proposed method enlarges the application range of LIF detector, and provides new approach for the analysis of certain compounds difficult to derivatize;(3) Based on the above research, an MEKC with indirect LIF detection method for the simultaneous determination of adenine and guanine in DNA extracts from fungus, maize and soybean was established;(4) A new method for the investigation of the complexes formed between human serum albumin and ampicillin sodium under the simulated physiology conditions using laser light scattering technique was developed.

该论文在综述前人工作的基础上,开展了如下未见文献报道的创新性的研究工作:(1)使用灵敏的衍生试剂对麻黄碱和伪麻黄碱在水体系中的衍生反应条件进行了系统研究,建立了微乳电动色谱-激光诱导荧光检测法和胶束电动色谱—激光诱导荧光检测法测定麻黄碱和伪麻黄碱的灵敏分析新方法,与以前的报道相比,灵敏度和分析时间均有很大改善;(2)使用荧光素钠作为背景荧光试剂,建立了同时分析测定六种黄酮类化合物(秦皮甲素、秦皮乙素、异秦皮定、染料木素、柚皮苷和槐角苷)的毛细管区带电泳—间接激光诱导荧光检测新方法,扩大了激光诱导荧光检测的应用范围,对难衍生化合物的分离分析提供了一种新思路和新途径;(3)以荧光素钠作为背景荧光试剂,建立了一种用于同时测定食品提取DNA中的腺嘌呤和鸟嘌呤含量的胶束电动色谱—间接激光诱导荧光检测新方法;(4)用动态和静态激光散射法研究了模拟生理条件下人血清白蛋白与氨比西林钠盐相互作用所形成的复合物,为药物分子与蛋白质的相互作用、药代动力学等的研究提供了一种新思路。

PCBs at the beginning of the land fill were mainly composed of the 3-Cl and 5-Cl compounds. In the late of the land fill, 2-Cl compounds increased significantly. The main factor affecting the PAHs, PCBs contents were microbial degradation and transformation. Analysis of the pollutants source s indicated that PAHs in sludge were mainly derived from the waste water of refinery, coking plant, gasworks, smelt plant and pitch plant.

填埋初期污泥中PCBs主要以3-Cl和5-Cl化合物为主,填埋后期,2-Cl化合物大大增加,占总的PCBs含量的大部分影响PAHs、PCBs含量变化的主要因素是生物对PAHS的降解转化根据污泥中各污染物的含量对污染物进行源解析表明,污泥中PAHs主要来源于炼油厂、炼焦厂、煤气厂、冶炼厂和沥青厂等排放的废水。

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