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This study was designed to investigate the mechanisms of histone deacetylase inhibitors(sulfonamide anilide compound referred as the "Compound") with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法：以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株；采用MTT法检测细胞生长抑制率；以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化；应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21waf/cif1 mRNA表达的变化。

This study was designed to investigate the mechanisms of histone deacetylase inhibitors (sulfonamide anilide compound referred as the Compound') with antitumor activity against human bladder cancer cells. MATERIALS AND METHODS: Treated with different concentrations of the Compound and HCPT for different periods of time, human bladder cancer cell line BIU-87 growthwas measured by MTT assay.

材料与方法：以不同浓度的Compound和羟基喜树碱作用于体外培养的膀胱癌BIU-87细胞株；采用MTT法检测细胞生长抑制率；以流式细胞术测定不同浓度的Compound和HCPT作用前后膀胱癌细胞的调亡情况及细胞周期的变化；应用RT-PCR分析Compound和HCPT作用前后膀胱癌细胞中P21(上标 waf/cif1)mRNA表达的变化。

Sulfonamide anilide compound could inhibit human bladder cancer cell growth in vitro, most likely through induction of P21(superscript waf/cif1) mRNA expression and subsequent arrest of cell cycling at G1 phase.

Compound在体外能有效抑制对传统化疗耐药的人膀胱癌细胞生长，其抗肿瘤生长机制可能是通过上调P21(上标 waf/cif1)mRNA水平从而使细胞阻滞于G1期所致。

Objective To investigate antitumor effect of compound traditional Chinese of cantharis injection, and to observe the protein expression of Fas in H22 tumor cells by treatment of CCI.

目的 研究复方斑蝥注射液(Compound Cantharis Injection， CCI)的抗肿瘤作用，并观察CCI对小鼠H22肿瘤细胞Fas蛋白表达的影响。

A novel SOI high voltage device with a compound dielectric buried layer is proposed,and an analytical model for its electric field and potential is established.A unified criterion of RESURF condition for CDL SOI and a uniform dielectric buried layer SOI device is given.

提出复合介质埋层SOI(compound dielectric buried layer SOI，CDL SOI)高压器件新结构，建立其电场和电势分布的二维解析模型，给出CDL SOI和均匀介质埋层SOI器件的RESURF条件统一判据。

This paper proposes a new probability model-Multivariate compound extreme value distribution to predict 'typhoon-induced rainfall for the Wenzhou City in Zhejiang Province.

作者采用多维复合极值分布理论(Multivariate compound extreme value distribution)，以受台风暴雨危害较严重的浙江温州地区为例，对台风诱发暴雨的降水量进行了概率预测。

ResultsPe Min Kam Wan, Lam Kam Sang Nasalin and Wo Chun Tong clearly inhibited PCA in mice and reduced histamine release from rat mast cells induced by compound 48/80. But,Sinuwell did not affect the PCA. In addition, the ethanol extracts from Senecio scandens, Selaginella tamariscina and Xanthium sibiricum significantly inhibited PCA in mice, but the extracts from Angelica dahurica, Magnolia liliflora and Cassia tora failed to affect it.

结果速效鼻敏感丸、林金生鼻敏清胶囊及和春堂鼻敏清片明显抑制小鼠异种被动皮肤过敏反应，减少compound 48/80诱导的组胺释放，而速效鼻敏素胶囊对被动皮肤过敏反应无明显影响；速效鼻敏感丸及和春堂鼻敏清片主要组成药物九里明、卷柏和苍耳子显著抑制小鼠异种被动皮肤过敏反应，而白芷、辛夷和决明子无明显作用。

At the web-based control page, it is able to upload our 2-D PAGE data and download the Tag Image File Format image. The 2-D PAGE data can be searched easily by limitation such as Peptide, NCBI Accession number, Map, Organisms, pI/Mw range, Drug/Compound, and Operator.

在这个网路管理介面内，我们可上传二维聚丙烯醯胺胶体的电泳资料、下载标志图形档案格式的影像图片，并且我们可以很容易的藉由如：蛋白质的名称、NCBI的登录号码、图像、胶片所使用的物种、蛋白质的等电点值与分子量范围（pI/Mw range）、胶片使用的抗生素或化合物（Drug/Compound）以及实验操作者等条件来搜寻二维聚丙烯醯胺胶体电泳资讯。

According to a thorough comparison and analysis of several classical criticality indexes including Path Criticality Probability, Activity Criticality Probability, Activity 'Cruciality' Index, all these indexes have limitations and pitfalls to some degree. Therefore, Activity Compound Criticality Index is presented as a compound index of ACP and ACI, and on the basis of ACCI, Project Compound Criticality Index, a new index that reflects the criticality of a whole project or subproject is proposed.

首先，对几个经典关键性指标——线路关键概率(Path Criticality Probability， PCP)、工序关键概率(Activity Criticality Probability， ACP)和工序关键指标(Activity Cruciality Index， ACI)——进行比较研究；鉴于各自利弊，提出一个 ACP 与 ACI 的整合指标——工序复合关键指标(Activity Compound Criticality Index，ACCI)，并进一步提出了一个表征项目整体&关键&水平的新指标项目——复合关键指标(Project Compound Criticality Index， PCCI)。

The result of polyhydroxy benzamides for whitening, the activity evaluation of tyrosinase inhibitory, it has apparently effect on the caffeic acid, gallic acid and 2, 5-dihydroxybenzoic acid of amide derivatives (IC50 = 62.41~130.28 μg/ml), but some of the compounds show apparently the activity of tyrosinase inhibitory,(ex:IC50 = 71.70 μg/ml of compound 12 and 57.26 μg/ml of compound 24) inhibitory efficacy.

多酚醯胺化合物在美白活性结果，抑制酪胺酸酶活性评估，以咖啡酸、没食子酸及2， 5-二羟基苯甲酸之醯胺衍生物效果最为显著(IC50 = 62.41~130.28 μg/ml)，但也有少酗坐あX物显示出明显抑制酪胺酸酶活性能力，如(Compound 12之IC50 = 71.70 μg/ml、Compound 24之IC50 = 57.26 μg/ml)也出现较强之抑制酪胺酸酶活性能力。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。