查询词典 colon

Objective To explore livin, MTA1 and the caspase3 protein expression, their correlation and clinical pathology in colon cancer Methods The expressions of livin, MTA1 and caspase3 protein in 88 cases of colon cancer were detected by immunohistochemistry stainingResults Livin, caspase3 protein and MTA1 positive expression rates in colon cancer tissues were more than those in tissues beside the cancer Furthermore there were obvious relevance between livin protein, MTA1 positive expression rate and degree of histodifferentiation and lymph node metabasis and between caspase3 protein positive expression rate and degree of histodifferentiation of colon cancer Caspase3 protein expression had prominent inverse correlation with the livin expressionConclusions ①Over expression of livin having inhibtion on colon cancer is one of important factors of colon carcinogenesis ②Caspase3 protein expression in colon cancer tissues is inhibited to less and has prominent inverse correlation with livin expression Accordingly, suppressing caspase3 protein activity is one of channels, by which livin promotes colon carcinogenesis ③MTA1 plays the important role in histodifferentiation degree and lymph node metastasis of colon cancer

采用免疫组织化学染色方法检测88例结肠癌组织中Livin，Caspase3 及MTA1的表达情况。结果（1）结肠癌组织中Livin的阳性表达率显著高于癌旁组织，且Livin的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（2）结肠癌组织中Caspase3蛋白的阳性表达率显著高于癌旁组织，且Caspase3蛋白的表达与结肠癌的组织分化程度显著相关。（3）结肠癌组织中MTA1的阳性表达率显著高于癌旁组织，且MTA1的表达与结肠癌的组织分化程度及淋巴结转移程度显著相关。（4）Caspase3蛋白的表达又与Livin的表达呈显著负相关。结论（1）Livin在结肠癌组织中过表达，它可能是促进结肠癌发生的重要因素之一。（2）Caspase3蛋白在结肠癌组织中表达被抑制而降低，且与Livin的表达呈负相关。因此，抑制Caspase3蛋白的活性是Livin促进结肠癌发生的途径之一。（3）MTA1对结肠癌的组织分化及淋巴转移发挥重要作用。

Results Well-resolved, reproducible 2-DE profiles of human colon carcinoma tissues and paired normal tumor-adjacent colon tissues were obtained. For colon carcinoma tissues, a total of (980±28) spots were detected; for paired normal tumor-adjacent colon tissues,(860±45) spots were detected. For normal tumor- adjacent colon tissues, the average deviation of spot position was (10.487±0.11) mm in IEF direction and (0.944±0.12) mm in SDS-PGE direction; for colon carcinoma tissues the average deviation of spot position was (0.654±0.11) mm in IEF direction and (1.20±0.22) mm in SDS-PGE direction. Number of differentially expressed proteins was 72.00±12.34 between colon carcinoma and paired normal tumor-adjacent colon tissues.

结果 建立了结肠癌及正常肠组织的双向凝胶电泳图谱，其中癌旁正常结肠组织和结肠癌组织电泳图谱中平均蛋白质点数分别为860±45和980±28；癌旁正常结肠组织和结肠癌组在IEF方向上的平均偏差分别为(0.487±0.11)mm和(0.654±11)mm，在SDS-PAGE方向上的平均偏差分别为(0.944±0.12)mm和(1.20±0.22)mm，结肠癌与癌旁正常结肠组织的差异表达蛋白质点数为72.00±12.34。

Results: 72 of 86 cases were ileal-colon type (83.7%), 14 cases were ileal-ileal-colon type (16.3%), which 25 cases lain in ileocecal junction, 17 cases in ascending colon, 14 cases in hepatic flexure of colon, 8 cases in transverse colon, 9 cases in splenic flexure of colon and 5 cases in decending colon.

结果：86例患者中，回－结肠型72例(83.7%)，回－回－结肠型14例(16.3%)，套头位于回盲部25例，升结肠17例，结肠肝曲14例，横结肠8例，结肠脾曲9例，降结肠5例。81例患者复位成功，成功率约94.2%。

Results: In 40 patients with rectum or colon carcinoma proven by pathology, there were 6 cases with cecum carcinomas, 3 cases with ascending colon carcinomas, 3 cases with transverse colon carcinomas, 5 cases with descending colon carcinomas, 1 case with-sigmoid colon carcinomas and 22 cases with rectum carcinomas.

结果：病理证实结直肠癌40例（其中盲肠癌6例，升结肠癌3例，横结肠癌3例，降结肠癌5例，乙状结肠癌1例，直肠癌22例），多层螺旋CT检出了全部结直肠癌，敏感性为100%，总的分期准确率为80%(32/40)，B期分期准确率为83.3%(15/l8)，C期分期准确率为66.7%(8/12)，肿瘤浆膜外侵犯的敏感性和特异性分别为95%(36/34)和50%(2/4)，淋巴结转移的敏感性和特异性分别为60%(12/20)和90%(9/10)。

Results Among 18 cases, there were 5 cases of rectal cancer, 6 cases of sigmoid colon carcinoma, 2 cases of sigmoid colonic polyp, 2 cases of descending colon carcinoma, 2 cases of ascending colon carcinoma and 1 case of ascending colonic lipoma.

结果 本组中直肠癌5例，乙状结肠癌6例，乙状结肠息肉2例，降结肠癌和升结肠癌各2例，升结肠脂肪瘤1例。

Results Among 3 cases of repetitive cancer,2 cases were homocheonou double cancer of ascending colon cancer and rectum cancer or of right colic flexure cancer and descending colon cancer,1 case was heterochronic triple cancer of stomach cancer、lung cancer and transverse colon cancer.

结果 3例重复癌患者，有2例同时性双重癌，分别患升结肠癌及直肠癌和结肠肝曲癌及降结肠癌，1例异时性三重癌，患有胃癌、肺癌、横结肠癌。

Animals tests showed that sphingomyelin could inhibit the development of abnormal colon crypt and colon tumor or cancer of ICR MOUSE induced by 1,2-dimethylhydrazine, by contributing to the protein expression of PCNA and Connexin26 in the tumor or cancer tissue, so sphingomyelin was considered to have the function of preventing colon cancer.

动物实验研究发现鞘磷脂能通过影响肿瘤组织中PCNA和Connexin 26蛋白表达，抑制1，2－二甲肼诱导的ICR小鼠异常结肠隐窝和结肠肿瘤的发生，因此对结肠癌有一定的预防作用。

Result: in three categories and ten examples of congenital malformation fetus, the morphological and histological structures of colon in syndactyly and sxtrodactyly fetus have no obvious abnormity; the colon's structure shows abnormity in omphalo-thoracopagus twins; the colon's structure was insufficient development in anencephaly fetus.

结果：三类10例先天性畸形胎儿中，并缺指畸形胎儿结肠的形态学及组织学结构无明显异常；胸腹联体胎儿结肠结构异常；无脑儿结肠组织结构发育不全。

Objective To study the preparation of berberine tannate colon-specific coated tablets, and investigate the effects of in vitro release conditions on the colon-targeting effects of the coated tablets and colon-targeted release.

目的 研究鞣酸小檗碱结肠定位包衣片的制备工艺，并考察体外释放条件对包衣片结肠定位及结肠释放行为的影响。

Berberine tannate colon-specific coated tablets was colon-targeted and satisfied the requirement for in vitro release of colon-specific delivery.

鞣酸小檗碱结肠定位包衣片可在结肠定位，且体外释放度满足结肠定位制剂的要求。

Objective To study the effect of chitosan in the prevention of fibrous scar formation in the epidural space after laminectomy.

目的 观察选择性脊神经后根切除术椎板切除后硬膜外几种防瘢痕粘连物质的作用并探讨其机制。

On his way to the lift, he looked back to us or was it me his eyes pointing?

当他要进电梯时，他回头看我们（或者说是我，他的眼光？